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Oral health status of Chinese residents and suggestions for prevention and treatment strategies 预览
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作者 Yan Si Baoiun Tai +9 位作者 Deyu Hu Huancai Lin Bo Wang Chunxiao Wang Shuguo Zheng Xuenan Liu Wensheng Rong Weijian Wang Xiping Feng Xing Wang 《全球健康杂志(英文)》 2019年第2期50-54,共5页
Objective:To understand the oral health status of urban and rural residents in China,the Fourth National Oral Health Epidemiological Survey (FNOHES) was conducted in 2015.Materials and methods:Based on the principles ... Objective:To understand the oral health status of urban and rural residents in China,the Fourth National Oral Health Epidemiological Survey (FNOHES) was conducted in 2015.Materials and methods:Based on the principles of multi-stage,stratified,equal capacity,and random sampling,the subjects included five groups of residents aged 3-5,12-15,35-44,55-64,and 65-74 years in all 31 provinces,municipalities,and autonomous regions except Hong Kong,Macao,and Taiwan.The total sample size was 172,425.The survey covered two areas,namely oral health status and knowledge,attitude and oral health behavior.Results:Residents in China had serious caries and poor periodontal condition.The prevalence of caries was above 50% in all age groups,subjects without periodontal disease accounted for <50%,and fewer than 50% of subjects brushed their teeth twice a day.Based on the results of the FNOHES,the following suggestions were proposed for improving the oral health in China in the future:to establish and improve the comprehensive prevention and control system for oral diseases,implement a comprehensive prevention and control strategy for priority groups,strengthen the oral health education for all people to improve oral health literacy,enhance dynamic monitoring to scientifically evaluate oral health status,and coordinate multi-party resources to establish and improve the oral health service security system.Conclusion:The oral health status of Chinese residents and their oral health behavior habits need to be improved.With the support of the administrative departments of the government and unremitting efforts of the oral health staff,all sectors of society must be coordinated to strengthen oral health education for the whole population.Furthermore,comprehensive prevention and control measures must be implemented for priority groups. 展开更多
关键词 CARIES PERIODONTITIS ORAL HEALTH ORAL disease EPIDEMIOLOGICAL study Comprehensive prevention and control The Fourth National ORAL HEALTH EPIDEMIOLOGICAL Survey
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广东省口腔预防保健状况调查研究 预览
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作者 杨晓霞 吴林梅 +4 位作者 范卫华 李剑波 王琼 黄少宏 阙国鹰 《现代医院管理》 2019年第1期13-17,共5页
目的 调查并分析广东省口腔预防卫生资源现状及近3年口腔疾病预防措施开展情况。方法 采用问卷调查方法对广东省21个市及其188个区/县/镇进行调查。问卷内容包括口腔疾病防治管理机构、口腔疾病防治专业机构的设立情况及近3年口腔疾病... 目的 调查并分析广东省口腔预防卫生资源现状及近3年口腔疾病预防措施开展情况。方法 采用问卷调查方法对广东省21个市及其188个区/县/镇进行调查。问卷内容包括口腔疾病防治管理机构、口腔疾病防治专业机构的设立情况及近3年口腔疾病预防措施开展情况。对问卷结果进行整理、统计和分析。结果 (1)95.2%的市有口腔疾病防治管理机构和口腔疾病防治专业机构;(2)45.7%的区/县/镇有口腔疾病防治管理机构,67.0%的区/县/镇有口腔疾病防治专业机构;(3)90.5%的市开展窝沟封闭,81.0%的市开展局部用氟,95.2%的市开展口腔健康教育,开展上述三项预防措施的区/县/镇比例分别为61.7%、44.1%和85.6%;有口腔疾病防治管理机构和口腔疾病防治专业机构的市及区/县/镇口腔疾病预防措施开展情况比无上述机构的市及区/县/镇好(P<0.01)。珠三角地区口腔疾病防治专业机构的设立情况及口腔疾病预防措施开展情况均较其他地区好(P<0.05)。结论 广东省各市口腔预防保健状况比较好,区/县/镇口腔预防保健状况不均衡,珠三角地区优于其他地区,应重点关注广东省区/县/镇和非珠三角地区口腔预防保健状况。 展开更多
关键词 口腔 卫生资源 口腔保健 问卷调查 广东省
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Motorcycle Related Oral and Maxillofacial Injuries Seen at Komfo Anokye Teaching Hospital, Kumasi-Ghana 预览
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作者 Alexander Oti Acheampong Merley Newman-Nartey +7 位作者 Solomon Obiri-Yeboah Jonathan Mensah Ama Amuasi Daniel Sabbah Jonathan Olesu Elijah Ebenezer Asamoah Robert Nii Lamy Larmie Peter Donkor 《外科学(英文)》 2019年第3期106-112,共7页
Background: Motorcycle related injuries have become a major public health problem because the increased use of motorcycles has been accompanied with a corresponding increase of road traffic accidents. Objective: The p... Background: Motorcycle related injuries have become a major public health problem because the increased use of motorcycles has been accompanied with a corresponding increase of road traffic accidents. Objective: The purpose of this study was to evaluate the occurrence of oral and maxillofacial injuries associated with motorcycles as seen at the second largest Teaching Hospital in Ghana, the Komfo Anokye Teaching Hospital (KATH). Method and Materials: The compiled data that were reviewed for this retrospective study were obtained from the Accident and Emergency unit of KATH. These comprised 135 successive maxillofacial trauma patient records entered from August 2017 to August 2018. Results: Total number of road traffic related injuries seen at OMFS was 135 during the study period. Out of this number, 66 were related to motorcycle injuries. This represented 48.7% of the Road Traffic Accidents seen at oral and maxillofacial surgery department (OMFS). The age range was from 3 to 64 years. The average age was 26.7 years. 62 (93.9%) were males and 4 (6.1%) were females. 16 (24.2%) of the motorcycle injuries were caused by the “Okada”, 2 (3.0%) by “Pragia” and 48 (72.8%) by the “Aboboyaa”. 46 (69.7%) of the motorcycles victims were themselves the riders, 12 (18.2%) were pedestrians and 8 (12.1%) were passengers. There were 8 deaths. 6 (75.0%) of the deaths were caused by the “Aboboyaa”. “Okada” accounted for only 2 (15.0%) deaths. Concerning the riders and the passengers, only 8 (14.8%) of the victims were helmeted. The majority were unhelmeted (85.2%). Conclusion: Motorcycle transportation is the cause of many oral and maxillofacial injuries. Majority of the victims suffered multiple facial bone fractures. Males were more often affected than females and the majority were unhelmeted. 展开更多
关键词 MOTORCYCLE ORAL MAXILLOFACIAL INJURIES Kumasi
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Arp2/3 Complex Is Expressed in Oral Squamous Cell Carcinoma: An Immunohistochemical Study of 88 Cases 预览
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作者 Marina P. Georgopoulou Konstantinos I. Tosios +1 位作者 Nikolaos Goutas Mirsini Kouloukoussa 《口腔学期刊(英文)》 2019年第3期29-38,共10页
Background: We investigated the immunohistochemical expression of Arp2/3 complex in 88 oral squamous cell carcinomas (OSCCs) and correlated it with the tumor type and grade. Materials and methods: This is a retrospect... Background: We investigated the immunohistochemical expression of Arp2/3 complex in 88 oral squamous cell carcinomas (OSCCs) and correlated it with the tumor type and grade. Materials and methods: This is a retrospective study of 88 cases of OSCCs (9 verrucous carcinomas, 4 carcinomas in situ, 37 well differentiated OSCCs, 32 moderately differentiated OSCCs, and 6 poorly differentiated OSCCs), stained with mouse monoclonal antibodies for Arp2 and Arp3. Staining was graded according to the extent of positivity by two observers. Results: Arp2 positivity was seen in 79 (89.77%) cases and Arp3 positivity in 78 (88.63%) cases. In positive cases, Arp2 expression was graded as (+) in 12.5%, (++) in 28.4% and (+++) in 48.86% of the cases;Arp3 was graded as (+) in 36.36%, (++) in 30.68% and (+++) in 21.59% of the cases. Conclusion: Expression of Arp2 and Arp3, indicative of the formation of the Arp2/3 complex, was seen in most OSCCs examined. Although no statistically significant correlation was found between the immunohistochemical expression of Arp2/Arp3 and tumor type or grade, the more common expression in invasive OSCCs than in non-invasive verrucous carcinomas and carcinomas in situ is indicative of its involvement in the biological behaviour of the lesions. The availability of Arp2/3 inhibitors that could be used in clinical practice warrants further study of the expression of Arp2/3 in OSCC. 展开更多
关键词 Actin-Related PROTEIN 2-3 Complex SQUAMOUS Cell CARCINOMA ORAL
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Deep learning for in vitro prediction of pharmaceutical formulations
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作者 Yilong Yang Zhuyifan Ye +3 位作者 Yan Su Qianqian Zhao Xiaoshan Li Defang Ouyang 《药学学报:英文版》 CSCD 2019年第1期177-185,共9页
Current pharmaceutical formulation development still strongly relies on the traditional trialand-error methods of pharmaceutical scientists. This approach is laborious, time-consuming and costly.Recently, deep learnin... Current pharmaceutical formulation development still strongly relies on the traditional trialand-error methods of pharmaceutical scientists. This approach is laborious, time-consuming and costly.Recently, deep learning has been widely applied in many challenging domains because of its important capability of automatic feature extraction. The aim of the present research is to apply deep learning methods to predict pharmaceutical formulations. In this paper, two types of dosage forms were chosen as model systems. Evaluation criteria suitable for pharmaceutics were applied to assess the performance of the models. Moreover, an automatic dataset selection algorithm was developed for selecting the representative data as validation and test datasets. Six machine learning methods were compared with deep learning. Results showed that the accuracies of both two deep neural networks were above 80% and higher than other machine learning models;the latter showed good prediction of pharmaceutical formulations. In summary, deep learning employing an automatic data splitting algorithm and the evaluation criteria suitable for pharmaceutical formulation data was developed for the prediction of pharmaceutical formulations for the first time. The cross-disciplinary integration of pharmaceutics and artificial intelligence may shift the paradigm of pharmaceutical research from experience-dependent studies to data-driven methodologies. 展开更多
关键词 PHARMACEUTICAL FORMULATION Deep learning Small data Automatic DATASET selection algorithm ORAL fast disintegrating films ORAL SUSTAINED release matrix TABLETS
Outcomes of per oral endoscopic pyloromyotomy in gastroparesis worldwide 预览
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作者 Parit Mekaroonkamol Rushikesh Shah Qiang Cai 《世界胃肠病学杂志:英文版》 SCIE CAS 2019年第8期909-922,共14页
Per oral endoscopic pyloromyotomy(POP),also known as gastric per-oral endoscopic myotomy(GPOEM),is a novel procedure with promising potential for the treatment of gastroparesis.As more data emerge and the procedure is... Per oral endoscopic pyloromyotomy(POP),also known as gastric per-oral endoscopic myotomy(GPOEM),is a novel procedure with promising potential for the treatment of gastroparesis.As more data emerge and the procedure is becoming more recognized in clinical practice,its safety and efficacy need to be carefully evaluated.Appropriate patient selection for favorable clinical success prediction after GPOEM also needs additional research.This review aims to systemically summarize the existing data on clinical outcomes of POP.Symptomatologic responses to the procedure,its adverse effects,procedural techniques,and predictive factors of clinical success are also discussed. 展开更多
关键词 Gastroparesis PER ORAL ENDOSCOPIC PYLOROMYOTOMY Gastric per-oral ENDOSCOPIC myotomy PYLOROMYOTOMY OUTCOMES
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Treatment of primary sclerosing cholangitis in children 预览
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作者 Trevor J Laborda M Kyle Jensen +1 位作者 Marianne Kavan Mark Deneau 《世界肝病学杂志:英文版(电子版)》 2019年第1期19-35,共17页
Primary sclerosing cholangitis (PSC) is a rare disease of stricturing and destruction of the biliary tree with a complex genetic and environmental etiology. Most patients have co-occurring inflammatory bowel disease. ... Primary sclerosing cholangitis (PSC) is a rare disease of stricturing and destruction of the biliary tree with a complex genetic and environmental etiology. Most patients have co-occurring inflammatory bowel disease. Children generally present with uncomplicated disease, but undergo a variable progression to endstage liver disease. Within ten years of diagnosis, 50% of children will develop clinical complications including 30% requiring liver transplantation. Cholangiocarcinoma is a rare but serious complication affecting 1% of children. Ursodeoxycholic acid and oral vancomycin therapy used widely in children as medical therapy, and may be effective in a subset of patients. Gamma glutamyltransferase is a potential surrogate endpoint for disease activity, with improved survival in patients who achieve a normal value. Endoscopic retrograde cholangiopancreatography is a necessary adjunct to medical therapy to evaluate mass lesions or dominant strictures for malignancy, and also to relieve biliary obstruction. Liver transplantation remains the only option for patients who progress to end-stage liver disease. We review special considerations for patients before and after transplant, and in patients with inflammatory bowel disease. There is presently no published treatment algorithm or guideline for the management of children with PSC. We review the evidence for drug efficacy, dosing, duration of therapy, and treatment targets in PSC, and provide a framework for endoscopic and medical management of this complex problem. 展开更多
关键词 Liver TRANSPLANT PEDIATRIC Ursodeoxycholic acid ORAL VANCOMYCIN ORAL VANCOMYCIN therapy Endoscopic RETROGRADE CHOLANGIOPANCREATOGRAPHY
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Oral Micronized or Parenteral Progesterone versus Health Education in the Prevention of Preterm Birth: A Single Blinded Randomized Controlled Trial 预览
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作者 Atef M. M. Darwish Alaa E. M. Ismail +1 位作者 Maher S. Mohammad Salah A. E. Gobara 《妇产科期刊(英文)》 2019年第5期612-623,共12页
The primary aim of this study was to evaluate the possible prophylactic role of progesterone in women with a history of spontaneous preterm birth (PTB) while the secondary aim was to compare oral or intramuscular prog... The primary aim of this study was to evaluate the possible prophylactic role of progesterone in women with a history of spontaneous preterm birth (PTB) while the secondary aim was to compare oral or intramuscular progesterone versus health education in such cases. Methods: A randomized, single blinded interventional randomized controlled trial was conducted. It comprised 90 cases with a history of PTB who were divided into 3 equal groups who received oral micronized progestogen capsule 200 mg daily (group A), parenteral 17 α-hydroxyprogesterone caproate 250 mg weekly IM injections (group B) or received health education including rest (group C) starting from 20 weeks till the end of 34 weeks of gestation. Results: This study included eligible 90 pregnant women at high risk of PTB who continued follow-up. For socio-demographic characteristics, there were no significant differences between the groups in respect to age, residence, education level, occupation, gravidity, parity and number of living children apart from significant difference between group A and C regarding mean patients’ age. Mode and place of delivery did not differ between the groups while gestational age at time of delivery was significantly better on using injectable than oral progesterone. Neonatal birth weight was significantly higher in group B if compared separately to groups A and C and was still significantly higher in group A if compared with group C. NICU admission rate was higher in group C if compared to group B or to the combined group A and B. Compliance was significantly higher in group B if compared to both group A and C and was significantly higher in the intervention group A and B if compared to group C. Conclusions: Progesterone supplementation has a significant role in prevention of PTB if compared with just health education. Progesterone injections expressed significantly better results than oral micronized progesterone in terms of prolongation of gestational age, better neonatal birth weight and less admission rate to the NIC 展开更多
关键词 PRETERM Birth ORAL INJECTABLE PROGESTERONE Health Education
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Oral manifestations in patients with diabetes mellitus 预览
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作者 Bita Rohani 《世界糖尿病杂志:英文版(电子版)》 2019年第9期485-489,共5页
The purpose of this article was to increase the knowledge about oral manifestations and complications associated with diabetes mellitus.An overview was performed on Google,especially in recent reliable papers in relat... The purpose of this article was to increase the knowledge about oral manifestations and complications associated with diabetes mellitus.An overview was performed on Google,especially in recent reliable papers in relation to diabetes mellitus and its oral manifestations(keywords were“diabetes mellitus”,“oral manifestations”,and“oral complications”).Data were collected and the results were declared.Diabetes mellitus is one of the most common chronic disorders characterized by hyperglycemia.This disease can have many complications in various regions of the body,including the oral cavity.The important oral manifestations and complications related to diabetes include xerostomia,dental caries,gingivitis,periodontal disease,increased tendency to oral infections,burning mouth,taste disturbance,and poor wound healing.Oral complications in diabetic patients are considered major complications and can affect patients’quality of life.There is evidence that chronic oral complications in these patients have negative effects on blood glucose control,so prevention and management of the oral complications are important. 展开更多
关键词 Diabetes MELLITUS ORAL complications ORAL MANIFESTATIONS PERIODONTAL disease XEROSTOMIA
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兔蛛网膜下腔出血应用尼莫地平治疗的生物利用度研究 预览 被引量:1
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作者 杨光 李香营 +1 位作者 王雄 陈晶 《海南医学院学报》 CAS 2019年第11期826-828,833共4页
目的:观察皮下注射尼莫地平和口服尼莫地平在健康兔和蛛网膜下腔充血(SAH)兔体内的生物利用度,并探讨皮下给药是否优于口服给药并达到目标血清浓度。方法:采用随机数字表法将成年雄性NZW兔36只分为6组(n=6):口服尼莫地平组(5、15mg/kg... 目的:观察皮下注射尼莫地平和口服尼莫地平在健康兔和蛛网膜下腔充血(SAH)兔体内的生物利用度,并探讨皮下给药是否优于口服给药并达到目标血清浓度。方法:采用随机数字表法将成年雄性NZW兔36只分为6组(n=6):口服尼莫地平组(5、15mg/kg组),皮下注射尼莫地平组(2.5、5、15mg/kg组),SAH+皮下注射尼莫地平组(2.5mg/kg),测量各组尼莫地平的血浆浓度并进行统计学分析。结果:(1)口服15mg/kg的尼莫地平会产生更高的峰值血浆浓度(Tmax),并且增加峰值血浆浓度(Cmax),曲线下面积(AUC)亦大于5mg/kg。对于皮下给药后观察到达到Tmax的时间具有相反的趋势,其中15mg/kg导致较低的Tmax,并且具有比5mg/kg更低的AUC倾向。(2)相比口服给药,皮下注射组的平均尼莫地平浓度显著大于7ng/mL(P<0.01),且尼莫地平血浆浓度保持在7ng/ml以上的时间明显大于口服给药(P<0.01)。(3)健康NZW兔中2.5mg/kg皮下尼莫地平产生的Cmax、Tmax和AUC值,与5和15mg/kg皮下注射后测量值无显著性差异(P>0.05)。在24h测量的平均尼莫地平浓度高于7ng/mL的目标治疗水平条件下,健康NZW兔(12.9±10.0)ng/mL和SAH(11.8±4.6)ng/mL兔差异亦无统计学意义(P> 0.05)。结论:皮下施用尼莫地平优于口服尼莫地平,并可以将24h后尼莫地平血浆水平维持在7ng/mL以上,有助于研究尼莫地平治疗SAH后延迟血管痉挛的机制。 展开更多
关键词 尼莫地平 皮下注射 口服 蛛网膜下腔出血 生物利用度
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Immunomodulatory properties of dental tissue-derived mesenchymal stem cells:Implication in disease and tissue regeneration 预览
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作者 Oleh Andrukhov Christian Behm +1 位作者 Alice Blufstein Xiaohui Rausch-Fan 《世界干细胞杂志:英文版(电子版)》 2019年第9期604-617,共14页
Mesenchymal stem cells(MSCs)are considered as an attractive tool for tissue regeneration and possess a strong immunomodulatory ability.Dental tissuederived MSCs can be isolated from different sources,such as the denta... Mesenchymal stem cells(MSCs)are considered as an attractive tool for tissue regeneration and possess a strong immunomodulatory ability.Dental tissuederived MSCs can be isolated from different sources,such as the dental pulp,periodontal ligament,deciduous teeth,apical papilla,dental follicles and gingiva.According to numerous in vitro studies,the effect of dental MSCs on immune cells might depend on several factors,such as the experimental setting,MSC tissue source and type of immune cell preparation.Most studies have shown that the immunomodulatory activity of dental MSCs is strongly upregulated by activated immune cells.MSCs exert mostly immunosuppressive effects,leading to the dampening of immune cell activation.Thus,the reciprocal interaction between dental MSCs and immune cells represents an elegant mechanism that potentially contributes to tissue homeostasis and inflammatory disease progression.Although the immunomodulatory potential of dental MSCs has been extensively investigated in vitro,its role in vivo remains obscure.A few studies have reported that the MSCs isolated from inflamed dental tissues have a compromised immunomodulatory ability.Moreover,the expression of some immunomodulatory proteins is enhanced in periodontal disease and even shows some correlation with disease severity.MSC-based immunomodulation may play an essential role in the regeneration of different dental tissues.Therefore,immunomodulation-based strategies may be a very promising tool in regenerative dentistry. 展开更多
关键词 Mesenchymal stem CELLS DENTAL TISSUE IMMUNOMODULATION Peripheral blood MONONUCLEAR CELLS Oral diseases TISSUE regeneration
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孕期口腔护理研究进展
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作者 曹常乐 王鑫 +2 位作者 郭琼 周纪妹 韩新光 《中国护理管理》 CSCD 北大核心 2019年第5期758-760,共3页
本文从孕期口腔内环境的变化、孕期口腔健康状况的评估工具、孕期口腔问题的预防和常见孕期口腔疾病及其护理4个方面对孕期口腔护理进行综述,以期为临床工作者提供参考。
关键词 孕期 口腔 护理 管理
口服和肌肉注射黄体酮治疗黄体功能不全所致先兆流产的临床效果及安全性对比分析 预览
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作者 叶飞雪 张月芳 黄臣 《内科》 2019年第5期526-528,共3页
目的比较口服和肌肉注射黄体酮治疗黄体功能不全所致先兆流产患者的临床效果及治疗安全性。方法选取2017年1月至2018年3月我院妇产科收治的黄体功能不全所致先兆流产患者90例作为研究对象,随机分成观察组与对照组,每组45例。观察组患者... 目的比较口服和肌肉注射黄体酮治疗黄体功能不全所致先兆流产患者的临床效果及治疗安全性。方法选取2017年1月至2018年3月我院妇产科收治的黄体功能不全所致先兆流产患者90例作为研究对象,随机分成观察组与对照组,每组45例。观察组患者口服黄体酮治疗,对照组患者肌肉注射黄体酮治疗,连续治疗2周,观察1个月。结果观察组患者的保胎成功率为93.33%,对照组患者的保胎成功率为91.11%,两组比较差异无统计学意义(P>0.05);两组患者的腰痛缓解时间、腹痛缓解时间、止血时间比较差异无统计学意义(P>0.05)。治疗期间,观察组患者的不良反应总发生率为6.7%,对照组为20.0%,两组比较差异有统计学意义(P<0.05)。结论口服及肌注黄体酮治疗先兆流产患者的保胎成功率及临床症状缓解效果差别不大,而口服治疗的不良反应发生率更低,值得在临床推广应用。 展开更多
关键词 黄体功能不全 先兆流产 黄体酮 口服 肌注
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不同种类托槽对儿童口腔微生态环境的影响 预览
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作者 马鹏涛 李晓琰 +1 位作者 韩永付 李华龙 《临床与病理杂志》 2019年第1期78-83,共6页
目的:探讨不同种类的托槽正畸治疗对儿童口腔微生态环境的影响。方法:选取郑州大学附属儿童医院2016年2月至2017年9月口腔门诊治疗的90例需要实施固定矫正的儿童,根据代用矫正器的类型分为传统组45例(采用传统托槽矫正治疗)、研究组45例... 目的:探讨不同种类的托槽正畸治疗对儿童口腔微生态环境的影响。方法:选取郑州大学附属儿童医院2016年2月至2017年9月口腔门诊治疗的90例需要实施固定矫正的儿童,根据代用矫正器的类型分为传统组45例(采用传统托槽矫正治疗)、研究组45例(采用自锁托槽矫正治疗);检测并对比两组儿童矫正治疗前(T0)、矫正治疗8周(T1)、矫正治疗12周(T2)时刻的龈沟液中IL-1β,TNF-α,IL-17A,IL-35水平;对比两组矫正前、矫正12周后的菌斑指数(plaque index,PLI)、牙龈指数(gingival index,GI)、龈沟出血指数(sulcus bleeding index,SBI)、龈沟液量及口腔寄生菌的情况。结果:矫正治疗前,研究组和传统组的PLI,GI,SBI及龈沟液量比较,差异不具有统计学意义(P>0.05);矫正治疗12周后,研究组的PLI,GI,SBI及龈沟液量均低于传统组(P<0.05);T0时刻,研究组和传统组的龈沟液IL-1β,TNF-α,IL-17A,IL-35水平比较,差异不具有统计学意义(P>0.05);T1,T2时刻,研究组的龈沟液IL-1β,TNF-α,IL-17A,IL-35水平均低于传统组(P<0.05)。治疗前,研究组和对照组的寄生菌检出率差异不具有统计学意义(P>0.05);矫正后12周,研究组的口腔寄生菌检出率低于传统组(P<0.05)。结论:自锁托槽矫正治疗与传统托槽均会对儿童口腔微生态环境造成一定的影响,但是前者影响程度较轻。 展开更多
关键词 正畸治疗 儿童 口腔 微生态环境
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9种口腔护理液对癌症患者口腔黏膜炎预防效果的网状Meta分析
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作者 喻雅婷 周新 +4 位作者 熊成敏 郑惠渊 唐佳 赵红 李原莉 《中国护理管理》 CSCD 北大核心 2019年第3期350-358,共9页
目的:用网状Meta分析评价9种口腔护理液预防癌症患者口腔黏膜炎(Oral Mucositis,OM)的应用效果。方法:计算机检索PubMed、Embase、Scopus、The Cochrane Library、Google Scholar、CNKI、维普、CBM和万方等数据库,搜集有关口腔护理液预... 目的:用网状Meta分析评价9种口腔护理液预防癌症患者口腔黏膜炎(Oral Mucositis,OM)的应用效果。方法:计算机检索PubMed、Embase、Scopus、The Cochrane Library、Google Scholar、CNKI、维普、CBM和万方等数据库,搜集有关口腔护理液预防OM的随机对照试验(RCT),检索时限均从建库至2018年8月。采用Cochrane手册对纳入RCT进行偏倚风险评估,由2位研究者独立提取及分析数据,采用Stata 15.0软件对所得的数据进行网状Meta分析。结果:共纳入28个RCT,包括1811例患者。网状Meta分析结果显示,9种口腔护理液预防OM效果中,与安慰剂比较,洗必泰、苄达明、蜂蜜和姜黄素分别在降低癌症患者OM发生率上差异有统计学意义(P<0.05);与聚维酮碘比较,蜂蜜和姜黄素能更有效降低OM的发生率,差异具有统计学意义(P<0.05),根据累积排序概率曲线下面积(SUCRA)值的大小对不同口腔护理液进行排序,排序结果从优到劣依次为姜黄素、蜂蜜、苄达明、洗必泰、别嘌呤醇、硫糖铝、GM-CSF、聚维酮碘、芦荟。结论:根据SUCRA排序结果得出姜黄素对癌症患者OM的预防效果优于其他口腔护理液,但本结论仍需更大样本的RCT进一步验证。 展开更多
关键词 黏膜炎 口腔 护理 癌症 网状Meta分析
A clinical study of Dangua Humai oral liquid on cardiovascular risk factors among patients with type 2 diabetes mellitus
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作者 衡先培 《中国医学文摘:内科学分册(英文版)》 2019年第2期69-70,共2页
Objective To study the influence of Dangua Humai oral liquid on inflammatory markers and cardiovascular prognosis among patients with high cardiovascular risks of type 2 diabetes mellitus. Methods A sample of 70 parti... Objective To study the influence of Dangua Humai oral liquid on inflammatory markers and cardiovascular prognosis among patients with high cardiovascular risks of type 2 diabetes mellitus. Methods A sample of 70 participants were randomly assigned to an experimental group(35 cases) and a control group(35 cases). 展开更多
关键词 A CLINICAL study Dangua Humai ORAL LIQUID PATIENTS with type
The Application of English Movies in Improving Oral English of College Students 预览
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作者 ZHANG Xia 《海外英语》 2019年第14期275-276,共2页
With the rapid development of China’s economy and information industry,the new generation has more opportunities to contact electric equipments.Through the investigation and study,the researcher found that the Englis... With the rapid development of China’s economy and information industry,the new generation has more opportunities to contact electric equipments.Through the investigation and study,the researcher found that the English movie is more suitable as the auxiliary materials to oral English teaching.So this article will discuss application of English movie in the college oral English teaching.It can provide variety materials for students to broaden horizon and enhance comprehensive ability. 展开更多
关键词 ENGLISH MOVIE ORAL ENGLISH COLLEGE students
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大学生口腔颜貌态度与自尊及幸福感相关研究 预览
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作者 吴雪辉 史敬存 +3 位作者 鲍俊翰 孙宝龙 刘毅赓 卢云 《全科口腔医学杂志(电子版)》 2019年第20期19-21,共3页
目的探讨大学生对口腔颜貌态度与自尊及总体幸福感相关性。方法针对大连高校578名大学生对口腔颜貌态度与自尊及总体幸福感进行统一问卷调查。结果大学生对口腔关注度不同与自尊水平存在显著相关性(P=0.012);大学生对颜貌重要性态度与... 目的探讨大学生对口腔颜貌态度与自尊及总体幸福感相关性。方法针对大连高校578名大学生对口腔颜貌态度与自尊及总体幸福感进行统一问卷调查。结果大学生对口腔关注度不同与自尊水平存在显著相关性(P=0.012);大学生对颜貌重要性态度与自尊水平、总体幸福感具有相关性(P=0.001,P=0.009);大学生对自己微笑满意度与其自尊心水平、生活满意度和总体幸福感具有显著相关性(P=0.000,P=0.000,P=0.000);大学生对自己牙齿美观关注度越高,其生活满意度、总体幸福感越高。结论大学生对口腔颜貌认知与自尊水平、生活满意度和总体幸福程度具有不同程度的相关性,口腔医师在相关治疗前应准确评估患者的状态,在治疗方案制定及沟通中注意,协助医患沟通,提高治疗效果。 展开更多
关键词 口腔 颜貌 自尊心 总体幸福感 大学生
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国内外口腔专科护士的培养与工作现状 预览
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作者 吴娜洁(综述) 陈静雅(审校) 《东南国防医药》 2019年第2期189-192,共4页
口腔护理学是具有口腔医学专业特点和专科护理技能的一门学科,对医护一体化要求较高。文章对国内外口腔专科护士的培养机制、准入条件、教学或培训内容、资格认证体系、工作现状等进行归纳,分析了我国现阶段口腔专科护士培养和工作中存... 口腔护理学是具有口腔医学专业特点和专科护理技能的一门学科,对医护一体化要求较高。文章对国内外口腔专科护士的培养机制、准入条件、教学或培训内容、资格认证体系、工作现状等进行归纳,分析了我国现阶段口腔专科护士培养和工作中存在的问题,以期为规范和完善我国口腔科护理工作提供依据。提高口腔专科护士的准入条件、重点培养其带教能力将有利于口专科护理人才的培养。 展开更多
关键词 口腔 专科护士 现状
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利湿健脾祛瘀汤结合西医常规疗法治疗口腔扁平苔藓临床研究
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作者 郭宝辉 王景文 宋辉 《国际中医中药杂志》 2019年第11期1193-1196,共4页
目的评价利湿健脾祛瘀汤结合西医常规疗法治疗口腔扁平苔藓(oral lichen planus,OLP)的疗效。方法将符合入选标准的80例OLP患者采用随机数字表法分为2组,每组40例。对照组采用常规疗法治疗,研究组在对照组基础上加服利湿健脾祛瘀汤。2... 目的评价利湿健脾祛瘀汤结合西医常规疗法治疗口腔扁平苔藓(oral lichen planus,OLP)的疗效。方法将符合入选标准的80例OLP患者采用随机数字表法分为2组,每组40例。对照组采用常规疗法治疗,研究组在对照组基础上加服利湿健脾祛瘀汤。2组均治疗4周。采用REU评分系统对病损情况进行评分,采用VAS量表评价口腔不适感,采用ELISA法检测血清TNF-α、IL-6、IL-8水平,采用流式细胞仪检测外周血CD3^+、CD4^+水平,计算CD4^+/CD8^+比值,评价临床疗效。结果研究组总有效率为82.5%(33/40)、对照组为62.5%(25/40),2组比较差异有统计学意义(χ^2=9.031,P=0.003)。治疗后,研究组血清TNF-α[(1.19±0.28)μg/L比(3.59±0.72)μg/L,t=19.807]、IL-6[(11.14±2.04)ng/L比(16.34±3.20)ng/L,t=8.666]、IL-8[(1.15±0.61)ng/L比(2.04±0.76)ng/L,t=5.776]水平均低于对照组(P<0.01);外周血CD3^+[(64.02±5.16)%比(58.07±4.85)%,t=5.314]、CD4^+[(41.26±3.61)%比(37.15±3.04)%,t=5.508]水平及CD4^+/CD8^+[(1.60±0.43)比(1.31±0.40),t=3.668]比值均高于对照组(P<0.01)。研究组治疗后REU评分与VAS评分均低于对照组(t值分别为10.980、11.146,P值均<0.01)。结论利湿健脾祛瘀汤结合西医常规疗法可有效改善OLP患者的临床症状,降低血清炎性细胞因子水平,增强机体免疫力,提高疗效。 展开更多
关键词 扁平苔癣 口腔 利湿健脾祛瘀汤 肿瘤坏死因子-α 白细胞介素 免疫重建
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