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Can mouse models mimic sporadic Alzheimer’s disease? 预览
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作者 Bettina MFoidl Christian Humpel 《中国神经再生研究:英文版》 SCIE CAS CSCD 2020年第3期401-406,共6页
Alzheimer’s disease(AD)is a progressive neurodegenerative disorder and the most common form of dementia worldwide.As age is the main risk factor,>97%of all AD cases are of sporadic origin,potentiated by various ri... Alzheimer’s disease(AD)is a progressive neurodegenerative disorder and the most common form of dementia worldwide.As age is the main risk factor,>97%of all AD cases are of sporadic origin,potentiated by various risk factors associated with life style and starting at an age>60 years.Only<3%of AD cases are of genetic origin caused by mutations in the amyloid precursor protein or Presenilins 1 or 2,and symptoms already start at an age<30 years.In order to study progression of AD,as well as therapeutic strategies,mouse models are state-of-the-art.So far many transgenic mouse models have been developed and used,with mutations in the APP or presenilin or combinations(3×Tg,5×Tg).However,such transgenic mouse models more likely mimic the genetic form of AD and no information can be given how sporadic forms develop.Several risk genes,such as Apolipoprotein E4 and TREM-2 enhance the risk of sporadic AD,but also many risk factors associated with life style(e.g.,diabetes,hypercholesterolemia,stress)may play a role.In this review we discuss the current situation regarding AD mouse models,and the problems to develop a sporadic mouse model of AD. 展开更多
关键词 Alzheimer’s disease BETA-AMYLOID cerebral AMYLOID ANGIOPATHY cognitive impairment SPORADIC and genetic mouse models tau vascular risk factors
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Systematizing IT Risks 预览
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作者 Georg Disterer 《信息安全(英文)》 2019年第4期237-249,共13页
IT risks—risks associated with the operation or use of information technology—have taken on great importance in business, and IT risk management is accordingly important in the science and practice of information ma... IT risks—risks associated with the operation or use of information technology—have taken on great importance in business, and IT risk management is accordingly important in the science and practice of information management. Therefore, it is necessary to systematize IT risks in order to plan, manage and control for different risk-specific measures. In order to choose and implement suitable measures for managing IT risks, effect-based and cause-based procedures are necessary. These procedures are explained in detail for IT security risks because of their special importance. 展开更多
关键词 IT RISK IT SECURITY RISK IT RISK MANAGEMENT COBIT ISO 27000
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高速公路路侧危险度评估模型 预览
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作者 黄煜镔 兰兴阳 +1 位作者 魏治国 石红星 《重庆交通大学学报:自然科学版》 CAS CSCD 北大核心 2019年第10期102-107,共6页
定量评价高速公路路侧危险度对解决高速公路安全防护设施不足或过剩问题以及制定安全改善方案具有重要的意义。通过研究将影响高速公路路侧安全性的因素概括为3个层次:事故潜在风险、事故暴露风险以及事故严重度风险,并基于路段的运行... 定量评价高速公路路侧危险度对解决高速公路安全防护设施不足或过剩问题以及制定安全改善方案具有重要的意义。通过研究将影响高速公路路侧安全性的因素概括为3个层次:事故潜在风险、事故暴露风险以及事故严重度风险,并基于路段的运行速度对事故严重度风险进行修正的基础上提出高速公路路侧危险度评估模型。利用该模型评估高速公路实际工程中的路侧危险度,实例分析表明评估模型有效合理。 展开更多
关键词 交通工程 路侧 危险度 潜在风险 暴露风险 严重度风险 运行速度
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邻避风险的放大过程及其弱化策略——基于风险的社会放大框架的分析 预览
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作者 王聪 《安徽行政学院学报》 2019年第5期101-106,共6页
众多邻避事件表明,邻避风险在与心理、社会、制度及文化的相互作用过程中被放大,产生了远远超出风险本身的涟漪效应。风险的社会放大框架为邻避风险的放大过程提供了理论阐发。邻避风险的主观属性和污名化特征是引入风险的社会放大框架... 众多邻避事件表明,邻避风险在与心理、社会、制度及文化的相互作用过程中被放大,产生了远远超出风险本身的涟漪效应。风险的社会放大框架为邻避风险的放大过程提供了理论阐发。邻避风险的主观属性和污名化特征是引入风险的社会放大框架的逻辑基础。邻避风险的社会放大经过了"风险感知—信息传播—社会反应—涟漪效应"四个阶段。因此,邻避风险治理应该从邻避风险的弱化着手,在邻避风险信号发出、传递的各个阶段通过风险披露、风险沟通、风险体验、风险柔性治理等策略层层弱化邻避风险,从而为邻避风险治理创造良好的社会环境。 展开更多
关键词 风险 邻避风险 社会放大 风险弱化
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全面风险管理视觉下的赴台学生风险防控措施研究 预览
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作者 杨先林 《湖北开放职业学院学报》 2019年第19期43-45,共3页
福建省高校近十几年来积极深入地开展与台湾高校在教育教学方面进行交流与合作,闽台高校联合培养人才项目的人才培养模式和发展规模等方面取得佳绩,形成了较好的发展态势。但由于闽台合作规模的增加、合作办学经验的欠缺及闽台诸类办学... 福建省高校近十几年来积极深入地开展与台湾高校在教育教学方面进行交流与合作,闽台高校联合培养人才项目的人才培养模式和发展规模等方面取得佳绩,形成了较好的发展态势。但由于闽台合作规模的增加、合作办学经验的欠缺及闽台诸类办学政策阻碍等多种因素影响下,闽台高校联合培养人才项目的学生赴台风险成了当前两岸高校管理者亟须正视的问题。本文从该项目的实际运作,结合高校风险理论,分析学生赴台的各种风险,从全面风险管理的角度探讨学生赴台风险的防控。 展开更多
关键词 风险 全面风险 风险防控
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互联网金融风险与防控
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作者 康宁 蒋东辉 《辽宁工程技术大学学报:社会科学版》 2019年第1期52-55,共4页
针对互联网金融风险防控问题,采用归纳分析的方法,分析了现阶段网络金融行业主要存在的监管风险,信用风险和内控风险,提出规范秩序,完善监管;加强风险防控能力;大力发展大数据,合理利用区块链技术等建议来促进互联网金融行业的持续、健... 针对互联网金融风险防控问题,采用归纳分析的方法,分析了现阶段网络金融行业主要存在的监管风险,信用风险和内控风险,提出规范秩序,完善监管;加强风险防控能力;大力发展大数据,合理利用区块链技术等建议来促进互联网金融行业的持续、健康的发展。 展开更多
关键词 金融 互联网金融 风险 信用风险 内控风险
新时代深化改革的风险与应对 预览
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作者 张青卫 高雅 《河北工程大学学报:社会科学版》 2019年第3期10-14,共5页
全面深化改革是推动当今之世社会发展的巨大动力。但改革的全面深化也出现各种深层次的矛盾,加剧了各种风险的产生。横向风险、纵向风险、操作风险、外来风险交融共生,贯穿于改革全过程和各领域。有效应对改革风险,既要有敢做敢当、积... 全面深化改革是推动当今之世社会发展的巨大动力。但改革的全面深化也出现各种深层次的矛盾,加剧了各种风险的产生。横向风险、纵向风险、操作风险、外来风险交融共生,贯穿于改革全过程和各领域。有效应对改革风险,既要有敢做敢当、积极主动的态度,更要注重科学管理。应不断强化风险意识,增强风险识别能力;科学分析风险存在机制,准确评估风险承受能力;加快立法进程,依法管理风险;注重各机构协调运作,加强统筹管理。唯有如此,才能真正做到破浪前行,勇立潮头,为世界各国防范和化解改革风险提供有益借鉴。 展开更多
关键词 改革 全面深化改革 风险 风险管理
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互联网金融背景下大学生金融风险及其防范对策的探讨 预览 被引量:6
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作者 程未 《长春金融高等专科学校学报》 2019年第1期14-17,24共5页
随着互联网金融的快速发展,第三方支付、P2P网贷等互联网金融服务在大学校园迅速传播,大学生所面临的金融风险在不断加大。个人信息泄露、财产损失、学业荒废甚至违法犯罪,大学生由于互联网金融而引发的一系列不幸事件使我们不得不重视... 随着互联网金融的快速发展,第三方支付、P2P网贷等互联网金融服务在大学校园迅速传播,大学生所面临的金融风险在不断加大。个人信息泄露、财产损失、学业荒废甚至违法犯罪,大学生由于互联网金融而引发的一系列不幸事件使我们不得不重视大学生金融风险问题。引导学生在合理接受互联网金融服务、提高自身生活品质的同时,正确认识并规避相应的金融风险是高校教育必须长期面对的一个问题。 展开更多
关键词 大学生 互联网金融 风险 防范
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广东省农村拆旧复垦模式风险分析 预览
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作者 邓婷 吴家龙 《广东土地科学》 2019年第2期19-23,共5页
通过对广东省农村闲置建设用地进行拆旧复垦,能够有效地解决现行土地管理中城市建设用地不足和农村集体建设用地浪费的矛盾。考虑到目前拆旧复垦模式仍处于探索阶段,因此,在农民、政府、农用地监管及相关政策的冲突方面存在着一定的风... 通过对广东省农村闲置建设用地进行拆旧复垦,能够有效地解决现行土地管理中城市建设用地不足和农村集体建设用地浪费的矛盾。考虑到目前拆旧复垦模式仍处于探索阶段,因此,在农民、政府、农用地监管及相关政策的冲突方面存在着一定的风险。本文对相关风险进行了分析并提出了相关的防控措施,以期为广东省以及其他地区拆旧复垦工作提供参考。 展开更多
关键词 拆旧 复垦 存在风险 风险防控
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The New Approach for Risk Regulation in Banks 预览
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作者 Daniela Feschiyan Radka Andasarova 《中国经济评论:英文版》 2019年第1期30-36,共7页
The purpose of this report is to present the necessity of proceeding to new reforms in bank regulation and to increase the stability and risk sensitivity of the capital base under applying the Standardised Credit Risk... The purpose of this report is to present the necessity of proceeding to new reforms in bank regulation and to increase the stability and risk sensitivity of the capital base under applying the Standardised Credit Risk Assessment Approach (SCRA) in banks. The dynamics in the bank regulation and supervision of credit risk assessment approaches are explored. In the paper, a thorough theoretical-methodological and historical-logical analysis was made of the evolution of the development and chronology of the global regulatory frameworks for banks—Basel 1, Basel 2, and Basel 3. The contemporary projections and challenges for the banks’ management under the new regulatory and institutional changes are presented. The SCRA is a positive asset in bank capital regulation in contemporary banking. The revisions to the regulatory framework by Basel 3 are a long continuous process influenced by numerous economic, social, and political factors. The preparation of the Bulgarian banking system for a new reform of financial regulation is analyzed. The need for adoption of a new risk-based approach for capital assessment and the importance of transparency in bank financial reporting is proved. 展开更多
关键词 BASEL Committee on BANKING Supervision (BCBS) standardised APPROACH (SA) credit RISK bank EXPOSURES risk-weighted assets (RWA)
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Biomarkers enhance the long-term predictive ability of the KAMIR risk score in Chinese patients with ST-elevation myocardial infarction
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作者 Jian-Jun Wang Yan Fan +5 位作者 Yan Zhu Jian-Dong Zhang Su-Mei Zhang Zhao-Fei Wan Hong-Ling Su Na Jiang 《中华医学杂志:英文版》 SCIE CAS CSCD 2019年第1期30-41,共12页
Background:The Global Registry of Acute Coronary Events (GRACE) score is recommended by current ST-elevation myocardial infarction (STEMI) guidelines.But it has inherent defects.The present study aimed to investigate ... Background:The Global Registry of Acute Coronary Events (GRACE) score is recommended by current ST-elevation myocardial infarction (STEMI) guidelines.But it has inherent defects.The present study aimed to investigate the more compatible risk stratification for Chinese patients with STEMI and to determine whether the addition of biomarkers to the Korea Acute Myocardial Infarction Registry (KAMIR) score could enhance its predictive value for long-term outcomes.Methods:A total of 1093 consecutive STEMI patients were included and followed up 48.2 months.Homocysteine,hypersensitive C-reactive protein (hs-CRP),and N-terminal pro-B-type natriuretic peptide (NT-proBNP) were detected.The KAMIR score and the GRACE score were calculated.The performance between the KAMIR and the GRACE was compared.The predictive power of the KAMIR alone and combined with biomarkers were assessed by the receiver-operating characteristic (ROC) curve.Results:The KAMIR demonstrated a better risk stratification and predictive ability than the GRACE (death:AUC = 0.802 vs.0.721,P<0.001;major adverse cardiovascular events (MACE):AUC = 0.683 vs.0.656,P<0.001).It showed that the biomarkers could independently predict death [homocysteine:HR= 1.019 (1.015–1.024),P<0.001;hs-CRP:HR= 1.052 (1.000–1.104),P= 0.018;NT-pro BNP:HR= 1.142 (1.004–1.280),P= 0.021] and MACE [homocysteine:HR= 1.019 (1.015–1.024),P<0.001;hs-CRP:HR= 1.012 (1.003–1.021),P= 0.020;NT-pro BNP:HR= 1.136 (1.104–1.168),P= 0.006].When they were used in combination with the KAMIR,the area under the ROC curve (AUC) significantly increased for death [homocysteine:AUC = 0.802 vs.0.890,Z = 5.982,P<0.001;hs-CRP:AUC = 0.802 vs.0.873,Z= 3.721,P<0.001;NT-pro BNP:AUC= 0.802 vs.0.871,Z = 2.187,P= 0.047;homocysteine,hs-CRP and NT-pro BNP:AUC = 0.802 vs.0.940,Z = 6.177,P<0.001] and MACE [homocysteine:AUC = 0.683 vs.0.771,Z= 6.818,P<0.001;hs-CRP:AUC= 0.683 vs.0.712,Z= 2.022,P= 0.031;NT-pro BNP:AUC= 0.683 vs.0.720,Z= 2.974,P= 0.003;homocysteine,hs-CRP and NT-pro BNP:AUC= 0.683 vs.0.789,Z= 6.900, 展开更多
关键词 ST-elevation MYOCARDIAL INFARCTION the Korea ACUTE MYOCARDIAL INFARCTION REGISTRY RISK SCORE the Global REGISTRY of ACUTE Coronary Events RISK SCORE homocysteine hypersensitive C-reactive protein N-terminal pro-B-type natriuretic peptide
Podiatric Risk Assessment in Diabetic Patients at University Hospital Center of Point G 预览
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作者 Sy Djibril Traoré Abdel Kader +24 位作者 Soukho Assétou Kaya Traoré Djenebou Thomas Ingrid Gladys Keita Zakaria Dembelé Ibrahima Amadou Cissoko Mamadou Sangaré Barry Boubacar Togo Mamadou Ke?ta Kaly Keita Adramé Tolo Nagou Camara Boua Daoud Dao Karim Doumbia Alassane Alfousseni Saliou Mahamadou Fofana Youssouf Mallé Mamadou Traoré Abdramane Sangaré Drissa Cissé Sékou Mamadou Berthé Brehima Boly Sanogo Abasse Sy Seydou Dembélé Mamadou Traoré Hamar Alassane 《内分泌与新陈代谢疾病期刊(英文)》 2019年第8期85-94,共10页
Introduction: Diabetes, a chronic pathology, is the source of many acute and chronic complications whose treatment requires many daily constraints that can have a serious impact on the quality of life of the patient a... Introduction: Diabetes, a chronic pathology, is the source of many acute and chronic complications whose treatment requires many daily constraints that can have a serious impact on the quality of life of the patient and his family. The diabetic foot is a real public health problem which is still dominated by a very high lower limb amputation rate even in countries with high socioeconomic status. The diabetic foot classically results from the association of three entangled mechanisms which are neuropathy, arteriopathy and infection. Objectives: To determine the frequency of arterial disease, neuropathy, and other aggravating factors that influence the podiatry risk, and to proceed with the gradation of the podiatry risk. Methodology: This was a cross-sectional study concerning the period from July 1 to October 31, 2017, covering all diabetic patients received in consultation and hospitalization in the Internal Medicine Department of the G-University Hospital Center. Results: Our study included 50 patients (35 women for 15 men) out of 95 diabetic patients receiving a frequency of 52.6%, with a sex ratio of 0.42. The average age of our patients was 54.38 ± 13.98 years. Overweight/obesity found in 44% of patients. The average Body Mass Index (BMI) of our patients was 27.16 kg/m2. Patients with diabetes less than 5 years old represented 56% with an average duration of 5.39 ± 5.34 years. The mode of discovery of diabetes was polyuria-polydipsia syndrome in 56% of cases. Type 2 diabetes represented 74% of patients. Among the patients who had performed the HbA1C test, 80.77% were not well balanced. The antecedent of macrosomia in women accounted for 77.1%. Patients who did not know foot hygiene recommendations accounted for 82%. Among the identified podiatry risk factors, diabetic neuropathy accounted for 73.8%, and arterial disease was 32.3%. Grade 1 patients in our study accounted for 52% (gradation of foot risk). Conclusion: The diabetic foot is a major public health problem because of its frequency, its direct and 展开更多
关键词 Monitoring DIABETES FOOT Risk MALI
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后迟滞型风险沟通及其精准治理
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作者 吴长剑 《吉首大学学报:社会科学版》 CSSCI 北大核心 2019年第6期99-107,共9页
随着“外部风险”被“人为风险”替代和主导,西方发达国家积极推动传统风险沟通向现代风险沟通转变。后发国家在全球化风险和本地化风险双重冲击下,呈现出迟滞型风险沟通。我国互联网新媒体浪涌式发展,催化了风险沟通主体与互联网新媒... 随着“外部风险”被“人为风险”替代和主导,西方发达国家积极推动传统风险沟通向现代风险沟通转变。后发国家在全球化风险和本地化风险双重冲击下,呈现出迟滞型风险沟通。我国互联网新媒体浪涌式发展,催化了风险沟通主体与互联网新媒体手段产生“粘合”及“轮推作用”,迟滞型风险沟通由此向后迟滞型风险沟通嬗变。透过转基因食品风险辩论案例交互机制,发现后迟滞型风险沟通存在“局部性突破”和“局部性落差”双重不确定性效果。为此,可通过主动预防型理念、“共同体”结构、“多速整合”机制、“互联网+”手段、政府职能的“五位一体”再造,实现对后迟滞型风险沟通不良后果的精准治理。 展开更多
关键词 风险 风险社会 后迟滞型风险沟通 轮推作用 转基因食品 精准治理
基于AHP的交行阜新分行内部控制制度有效性分析
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作者 刘春刚 《辽宁工程技术大学学报:社会科学版》 2019年第3期217-223,共7页
针对内部控制制度有效性问题,采用层次分析法和模糊评价法对交通银行阜新分行内部控制制度进行分析,在内部控制指引5要素的基础上建立了评价指标体系,利用层次分析法进行权重处理,阜新分行的内部控制制度能有效地防范公司的经营风险,但... 针对内部控制制度有效性问题,采用层次分析法和模糊评价法对交通银行阜新分行内部控制制度进行分析,在内部控制指引5要素的基础上建立了评价指标体系,利用层次分析法进行权重处理,阜新分行的内部控制制度能有效地防范公司的经营风险,但在风险识别、风险应对和资产处置等方面控制薄弱,需要有针对性的改进。 展开更多
关键词 内部控制 控制环境 风险 风险评估 层次分析法
Predicting systemic spread in early colorectal cancer: Can we do better? 预览
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作者 Scarlet Fiona Brockmoeller Nicholas Paul West 《世界胃肠病学杂志:英文版》 SCIE CAS 2019年第23期2887-2897,共11页
Through the implementation of national bowel cancer screening programmes we have seen a three-fold increase in early pT1 colorectal cancers, but how these lesions should be managed is currently unclear. Local excision... Through the implementation of national bowel cancer screening programmes we have seen a three-fold increase in early pT1 colorectal cancers, but how these lesions should be managed is currently unclear. Local excision can be an attractive option, especially for fragile patients with multiple comorbidities, but it is only safe from an oncological point of view in the absence of lymph node metastasis. Patient risk stratification through careful analysis of histopathological features in local excision or polypectomy specimens should be performed according to national guidelines to avoid under-or over-treatment. Currently national guidelines vary in their recommendations as to which factors should be routinely reported and there is no established multivariate risk stratification model to determine which patients should be offered major resectional surgery.Conventional histopathological parameters such as tumour grading or lymphovascular invasion have been shown to be predictive of lymph node metastasis in a number of studies but the inter-and intra-observer variation in reporting is high. Newer parameters including tumour budding and poorly differentiated clusters have been shown to have great potential, but again some improvement in the inter-observer variation is required. With the implementation of digital pathology into clinical practice, quantitative parameters like depth/area of submucosal invasion and proportion of stroma can be routinely assessed. In this review we present the various histopathological risk factors for predicting systemic spread in pT1 colorectal cancer and introduce potential novel quantitative variables and multivariable risk models that could be used to better define the optimal treatment of this increasingly common disease. 展开更多
关键词 Early colorectal CANCER Bowel CANCER screening Local RESECTION Major RESECTION Morphological RISK factors Conventional HISTOPATHOLOGY PARAMETERS Novel HISTOPATHOLOGY PARAMETERS RISK STRATIFICATION models Digital pathology
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Exploring the Differences between Hispanic Men and Women with Type 2 Diabetes Mellitus Using the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) 预览
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作者 Madeleine Morin Erin St. Onge 《食品与营养科学(英文)》 2019年第7期713-718,共6页
Studies have shown Hispanic patients are at an increasing risk of developing type 2 diabetes;however, little is known about whether gender plays a role. Several studies were examined to help answer this question. Resu... Studies have shown Hispanic patients are at an increasing risk of developing type 2 diabetes;however, little is known about whether gender plays a role. Several studies were examined to help answer this question. Results of studies found female Hispanic patients tend to be more sedentary and thus struggle more with obesity, while male Hispanic patients tend to be more at risk due to smoking status and hypercholesterolemia. In addition, psychological distress and chronic stress were more likely to affect the risk for diabetes in men while immigration status was more likely to affect cardiovascular health in women. More studies are needed to fully understand the role of gender on diabetes risk;however, practitioners can utilize known information in order to tailor treatment to male or female Hispanic patients. 展开更多
关键词 Hispanic Diabetes Risk CARDIOVASCULAR GENDER
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Risk assessment and zoning of sea level rise in Shandong Province 预览
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作者 LIU Qingrong LI Jian +5 位作者 RUAN Chengqing YIN Zhonghui JIAO Yan SUN Qing LIAN Xihu ZHONG Shan 《海洋湖沼学报(英文)》 SCIE CAS CSCD 2019年第6期2014-2024,共11页
Sea level rise is a slow-onset disaster.We collected information about the natural and ecological environments,tides and sea levels,and socio-economic aspects to investigate the distribution and zoning of the risks fr... Sea level rise is a slow-onset disaster.We collected information about the natural and ecological environments,tides and sea levels,and socio-economic aspects to investigate the distribution and zoning of the risks from sea level rise across Shandong Province.The trends in sea level in different counties of Shandong Province were predicted using moving averages and a random dynamic analysis forecasting model,and the model outputs and socio-economic indicators were combined to assess the risks.The results show that the risks of sea level rise along the western coast of Bohai Bay and Laizhou Bay in Shandong Province were sufficiently large to warrant attention. 展开更多
关键词 SEA level RISE RISK assessment RISK ZONING
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人工智能技术风险规避探析 预览
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作者 闫坤如 马少卿 《长沙理工大学学报:社会科学版》 2019年第4期7-12,共6页
随着人工智能日渐融入人类生活,人工智能的发展引发了学者的普遍关注,特别是人工智能技术引发的风险问题。人工智能给人类社会生活带来便利的同时,也可能引发隐私泄露风险、人的主体性地位丧失的风险以及带来新的社会风险。为了应对人... 随着人工智能日渐融入人类生活,人工智能的发展引发了学者的普遍关注,特别是人工智能技术引发的风险问题。人工智能给人类社会生活带来便利的同时,也可能引发隐私泄露风险、人的主体性地位丧失的风险以及带来新的社会风险。为了应对人工智能及智能技术的发展带来的各种问题,应该从规制隐私泄露、避免人的主体性地位丧失以及维护社会的安全与稳定等视角思考风险规避路径。 展开更多
关键词 人工智能 风险 社会风险 道德嵌入
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医院全面风险管理体系构建分析 预览
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作者 盛永娇 和静淑 黄炜 《中国医药导报》 CAS 2019年第14期169-172,共4页
社会经济的不断发展使人民群众的健康意识不断提高,对医疗服务的要求也日益增加。随着医疗体制改革的持续推进,公立医院面临的风险越来越多,也越来越复杂。医院内部控制体系的建立已有一定基础,随着国家对建立健全现代医院管理制度试点... 社会经济的不断发展使人民群众的健康意识不断提高,对医疗服务的要求也日益增加。随着医疗体制改革的持续推进,公立医院面临的风险越来越多,也越来越复杂。医院内部控制体系的建立已有一定基础,随着国家对建立健全现代医院管理制度试点的开展,对现代医院管理提出了更高的要求,实施全面风险管理势在必然。本文以G中医医院为例,对其现有的风险管理现状进行分析。该医院在内部控制方面既取得了一定的成绩——建立了内部控制体系职能组织和内部控制体系框架基本完成,也存在一定的问题,如全面风险管理意识薄弱、内部控制体系未充分发挥作用等。笔者借鉴企业全面风险管理的经验对其构建全面风险管理体系提出了建立环境形成独特的风险管理文化、建立全面风险管理体系组织体系、建立风险管理信息系统等相关建议。 展开更多
关键词 医院 风险 全面风险管理 体系构建
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河北省雷电灾害风险区划研究 预览
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作者 陈柳彤 龙爽 +4 位作者 俞海洋 李倩 陈笑娟 王瑛 许映军 《灾害学》 CSCD 北大核心 2019年第3期189-195,共7页
河北省雷电灾害频发,造成重大损失,引发社会大量关注,2017年中国气象局发布了雷电灾害区划技术指南。雄安新区雷电灾害风险区划可以为新区发展规划提供参考。依据自然灾害分析原理,参照雷电灾害区划技术指南,选用致灾因子危险性和承灾... 河北省雷电灾害频发,造成重大损失,引发社会大量关注,2017年中国气象局发布了雷电灾害区划技术指南。雄安新区雷电灾害风险区划可以为新区发展规划提供参考。依据自然灾害分析原理,参照雷电灾害区划技术指南,选用致灾因子危险性和承灾体易损性为分析因子,利用2010-2016年河北省闪电定位网观测数据、地理信息数据及社会经济数据,选取地闪密度、地闪强度、土壤电导率、海拔高度以及地形起伏5个指标分析致灾因子的危险性,人口密度、GDP密度、防护能力以及城镇化率4个指标分析承灾体的易损性。通过计算雷电灾害风险指数,运用自然断点法,最终得到河北省雷电灾害风险区划。河北省雷电灾害高风险区分布于唐山市东南部、石家庄市、沧州市中东部、承德市东南部、张家口市西南部。雄安新区在进行雷电灾害防治时应重点关注容城县和雄县。该区划结果与河北省2015-2017年雷灾实际造成的经济损失状况大致相符。 展开更多
关键词 河北省 雷电灾害 危险性 脆弱性 风险区划 雄安新区
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