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Newly onset indirect traumatic optic neuropathy-surgical treatment first versus steroid treatment first
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作者 Bo Yu Ying-Jie Ma +1 位作者 Yun-Hai Tu Wen-Can Wu 《国际眼科杂志:英文版》 SCIE CAS 2020年第1期124-128,共5页
AIM: To investigate the efficacy and safety of the treatment of endoscopic trans-ethmosphenoid optic canal decompression(ETOCD) with combination of steroid in patients with newly onset indirect traumatic optic neuropa... AIM: To investigate the efficacy and safety of the treatment of endoscopic trans-ethmosphenoid optic canal decompression(ETOCD) with combination of steroid in patients with newly onset indirect traumatic optic neuropathy(ITON) and compare the outcome between immediate ETOCD treatment and ETOCD with preoperative steroid treatment. METHODS: Patients presented as newly onset ITON(suffered trauma within 3 d) at a tertiary medical center between Mar 1 st, 2016 and Mar 1 st, 2018 were enrolled in this study. All patients were equally and randomly divided into 2 groups. Cases in group A were performed ETOCD immediately after admition while cases in group B were prescribed by methylprednisolone(20 mg/kg · d) for 3 d before ETOCD. Methylprednisolone(20 mg/kg · d) was used after surgery for 6 d in group A and 3 d in group B. Follow-up was up to 3 mo in all cases. Visual acuity(VA) before and after treatment between the two groups were taken into comparison. RESULTS: Complete postoperative data were acquired from 34 patients in group A and from 32 patients in group B. Group A had significantly higher effective rate in VA than group B(χ~2 =4.905, P=0.027).CONCLUSION: For patients with newly onset ITON, combination treatment of ETOCD with high-dose steroid is an effective and safe way. Immediate surgery will lead to better prognosis for these cases. 展开更多
关键词 indirect traumatic optic neuropathy endoscopic trans-ethmosphenoid optic canal decompression STEROID visual acuity newly onset
Pathogenic Characterization and Full Length Genome Sequence of a Reassortant Infectious Bursal Disease Virus Newly Isolated in Pakistan
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作者 Altaf Hussain Tiantian Wu +15 位作者 Hui Li Linjin Fan Kai Li Li Gao Yongqiang Wang Yulong Gao Changjun Liu Hongyu Cui Qing Pan Yanping Zhang Asim Aslam Khan Muti-Ur-Rehman Muhammad Munir Salman Latif Butt Xiaomei Wang Xiaole Qi 《中国病毒学:英文版》 CAS CSCD 2019年第1期102-105,共4页
Dear Editor,Infectious bursal disease (IBD) is one of the most important diseases of the poultry. The IBD virus (IBDV), a nonenveloped virus belonging to the Birnaviridae family with a genome consisting of two segment... Dear Editor,Infectious bursal disease (IBD) is one of the most important diseases of the poultry. The IBD virus (IBDV), a nonenveloped virus belonging to the Birnaviridae family with a genome consisting of two segments of double-stranded RNA (segments A and B), targets B lymphocytes of bursa of Fabricious leading to immunosuppression. In Pakistan,poultry farming is the second biggest industry and IBD is the second biggest disease threating the poultry sector.However. 展开更多
关键词 In PATHOGENIC CHARACTERIZATION and Full LENGTH Genome Sequence of a REASSORTANT Infectious Bursal Disease Virus NEWLY ISOLATED in Pakistan
Newly developed two-dimensional materials for efficient photocatalytic hydrogen evolution
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作者 Xueying Zhan Fengmei Wang +2 位作者 Zhongzhou Cheng Zhenxing Wang Jun He 《科学通报:英文版》 SCIE EI CSCD 2019年第14期958-960,共3页
Due to the increasing environmental and energy issues, hydrogen, as a clean and non-carbon energy source, has received more and more attention in the past decades. Photocatalysis has been known as a promising approach... Due to the increasing environmental and energy issues, hydrogen, as a clean and non-carbon energy source, has received more and more attention in the past decades. Photocatalysis has been known as a promising approach for hydrogen generation and a key measure in solving serious environmental problems. Different from traditional catalysts, such as ZnO and TiO2, two-dimensional (2D) materials display unique advantages to hydrogen production due to their large specific surface area, high charge migration rate, tunable electronic structure and ultra-lightweight [1]. Especially, 2D materials show short migration distance for the generated electrons and holes, leading to the reduction of electron-hole recombination, which is one of the key factors affecting photocatalytic efficiency [2-4]. 展开更多
关键词 NEWLY DEVELOPED TWO-DIMENSIONAL MATERIALS PHOTOCATALYTIC HYDROGEN evolution HYDROGEN generation
Newly Approved National Standards of P.R.China No.6,2019
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《中国标准化:英文版》 2019年第4期I0002-I0015,共14页
State Administration for Market Regulation and Standardization Administration of China have approved the following 173 national standards and 3 national standards with amendment.
关键词 NEWLY Approved NATIONAL STANDARDS P.R.China No.6 2019
Newly Approved National Standards of P.R.China No.7,2019
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《中国标准化:英文版》 2019年第4期I0016-I0046,共31页
State Administration for Market Regulation and Standardization Administration of China have approved the following 374 national standards and 3 national standards with amendment.
关键词 NEWLY Approved NATIONAL STANDARDS P.R.China No.7 2019
Updates in version 2019 of CSCO guidelines for colorectal cancer from version 2018 预览
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作者 Ying Yuan Xicheng Wang +10 位作者 Gong Chen Yi Wang Weiqi Sheng Xinxiang Li Aiping Zhou Zhen Zhang Guichao Li Sanjun Cai Ruihua Xu Jin Li Suzhan Zhang 《中国癌症研究:英文版》 SCIE CAS CSCD 2019年第3期423-425,共3页
According to the latest data from cancer registration center, there are estimated to be 3,929,000 individuals newly diagnosed with cancer and 2,338,000 deaths from this disease in China in 2015 (1). Among them, colore... According to the latest data from cancer registration center, there are estimated to be 3,929,000 individuals newly diagnosed with cancer and 2,338,000 deaths from this disease in China in 2015 (1). Among them, colorectal cancer (CRC) with 388,000 newly diagnosed cases and 187,000 deaths, stands the third place in incidence and the fifth place in mortality. The Chinese Society of Clinical Oncology (CSCO) has organized an expert committee to write and publish the Guideline for Colorectal Cancer in 2017. And its English version has already been published in March 2019 (2). According to the latest progress, the expert committee updated the guideline to the 2019 version in this April, and the summary of the main updates are as following. 展开更多
关键词 According to the latest individuals NEWLY are as FOLLOWING
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Expression of CRLF2 in adult Ph negative acute B lymphocytic leukemia and its prognostic significance
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作者 陈昊 《中国医学文摘:内科学分册(英文版)》 2018年第4期232-233,共2页
Objective To detect the expression of CRLF2 in adult Ph negative acute B lymphocytic leukemia(B-ALL)in newly diagnosed cases,and to investigate the relationship between CRLF2 and the general clinical characteristics,e... Objective To detect the expression of CRLF2 in adult Ph negative acute B lymphocytic leukemia(B-ALL)in newly diagnosed cases,and to investigate the relationship between CRLF2 and the general clinical characteristics,efficacy and prognosis.Methods 103 cases of newly diagnosed adult B-ALL patients were investigated from Apr 2016 to Dec 2017 in the Department of Hematology,Henan Cancer Hospital.Bone marrow samples were used to detect the expression of CRLF2 in leukemic cells.The expression of CRLF2≥20% was defined as CRLF2-high group and<20% was defined as CRLF2-low group.The clinical characteristics and prognosis of the two groups were compared.Results The Median overall survival(OS)and disease free survial(DFS)in CRLF2-high group were 9.0 months and 4.25 months,respectively.CRLF2-low group was 15.5 months and 10.25 months,respectively.There was a statistically significant difference in median OS and DFS between the two groups(P=0.007,P=0.000).The 18-month OS and DFS in CRLF2-high group were 38.6% and 25.1%,respectively.CRLF2-low group was 57.8% and 42.3%,respectively.Multivariate analysis showed high expression of CRLF2 was an independent risk factor for OS(HR=2.991,95% CI 1.429-6.261,P=0.004)and DFS(HR=2.374,95% CI 1.146-4.960,P=0.041)in patients.Conclusion Patients with high expression of CRLF2 have poor prognosis. 展开更多
关键词 the RELATIONSHIP NEWLY diagnosed CASES
Cost-effectiveness Analysis of Two Therapeutic Regimens for Newly Diagnosed Smear-negative Pulmonary Tuberculosis 预览
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作者 CHEN Liang MEI Jin Zhou +7 位作者 CHEN Xun Xun FENG Hui Ying WANG Jia Wen LI Hai Cheng XU Guang Hui XIAO Ling Wen HUANG Yi Xiang ZHOU Lin 《生物医学与环境科学:英文版》 SCIE CAS CSCD 2018年第8期623-626,共4页
Tuberculosis (TB) has a severe effect on humanhealth and causes a huge economic burden.Previous studies have demonstrated that patientswith smear-negative pulmonary TB accounted forapproximately 60%-70% of the total... Tuberculosis (TB) has a severe effect on humanhealth and causes a huge economic burden.Previous studies have demonstrated that patientswith smear-negative pulmonary TB accounted forapproximately 60%-70% of the total pulmonary TBcases. Therefore, it is extremely important toformulate safe, effective, and economic therapeuticregimens for patients with smear-negativepulmonary TB. 展开更多
关键词 COST-EFFECTIVENESS Analysis NEWLY Diagnosed Smear-negative PULMONARY TUBERCULOSIS
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基于心理授权的培训模式对新毕业护士工作胜任力的影响 预览 被引量:3
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作者 沈月 孙璇 万永慧 《现代临床护理》 2018年第7期57-61,共5页
目的 探讨基于心理授权的培训模式对提高新毕业护士工作胜任力的效果。方法 将2016年本院入职的221名新毕业护士设为对照组,在培训中采用理论授课和专科操作培训;将2017年本院入职的219名新毕业护士设为观察组,采用基于心理授权的培训... 目的 探讨基于心理授权的培训模式对提高新毕业护士工作胜任力的效果。方法 将2016年本院入职的221名新毕业护士设为对照组,在培训中采用理论授课和专科操作培训;将2017年本院入职的219名新毕业护士设为观察组,采用基于心理授权的培训模式进行干预,两组培训时间均为6个月。培训前后对两组新毕业护士的心理授权水平和胜任力进行测评和比较。结果 培训后,观察组新毕业护士心理授权总分与工作胜任力总分均高于对照组,两组比较,差异均有统计学意义(P〈0.05)。结论 基于心理授权的培训模式能有效提高新毕业护士的心理授权水平,最终达到提升新毕业护士胜任力,对新毕业护士完成角色转变起到促进作用。 展开更多
关键词 新毕业 护士 心理授权 护士胜任力
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Statistics of Railway Tunnels in China as of 2017 预览
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《隧道建设(中英文)》 北大核心 2018年第3期506-513,共8页
Overview of railway tunnels As of the end of 2017,the operating railway mileage in China had reached 127 000 km.About 14 547 tunnels with total length of 15 326 km had been put into operation.(1)Newly increased:465 ra... Overview of railway tunnels As of the end of 2017,the operating railway mileage in China had reached 127 000 km.About 14 547 tunnels with total length of 15 326 km had been put into operation.(1)Newly increased:465 railway tunnels with total length of 1 206 had been put into operation in 2017,among which there were 26 extra-long tunnels with total length of 368 km and 6 tunnels with single tunnel length over 15 km,as shown in Table 1.Extra-long tunnel refers to the tunnel with length over 10 km.Table 1 Newly increased extra-long railway tunnel with single tunnel length over 15 km in 2017,China(2)Under construction:3 825 tunnels with total length of 8 125 km were under construction.(3)Planned:5 596 tunnels with total length of 13 331 km were planned.2Overview of high-speed railway tunnels As of the end of 2017,the operating high-speed railway kilometerage in China had reached 25 000 km.About 2 835 tunnels with total length of 4 537 km had been constructed,among which there were 60 extra-long tunnels with total length of 775 km and 5 tunnels with single tunnel length over 15 km,as shown in Table 2.(1)Newly increased:6 high-speed railway lines with total length of 1 206 km had been put into operation in 2017;there were 198 tunnels with total length of 604 km,among which there were 16 extra-long tunnels with single tunnel length over 10 km and total length of 210 km,as shown in Table 3. 展开更多
关键词 NEWLY INCREASED HIGH-SPEED RAILWAY
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Supplementation of amylase combined with glucoamylase or protease changes intestinal microbiota diversity and benefits for broilers fed a diet of newly harvested corn 预览
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作者 Dafei Yin iaonan Yin +6 位作者 Xingyu Wang Zhao Lei Maofei Wang Yuming Guo Samuel E.Aggrey Wei Nie Jianmin Yuan 《畜牧与生物技术杂志:英文版》 SCIE CAS CSCD 2018年第2期467-479,共13页
Background:The effect of amylases combined with exogenous carbohydrase and protease in a newly harvested corn diet on starch digestibility,intestine health and cecal microbiota was investigated in broiler chickens.Met... Background:The effect of amylases combined with exogenous carbohydrase and protease in a newly harvested corn diet on starch digestibility,intestine health and cecal microbiota was investigated in broiler chickens.Methods:Two hunderd and eighty-eight 5-day-old female chickens were randomly divided into six treatments:a newly harvested corn-soybean meal diet(control);control supplemented with 1,500 U/gα-amylase(Enzyme A);Enzyme A+300 U/g amylopectase+20,000 U/g glucoamylase(Enzyme B);Enzyme B+protease 10,000 U/g(Enzyme C);Enzyme C+xylanase 15,000 U/g(Enzyme D);and Enzyme D+cellulase 200 U/g+pectinase 1,000 U/g(Enzyme E).Growth performance,starch digestibility,digestive organ morphology,and intestinal microbiota were evaluated in the birds at 16 and 23 d of age.Results:Compared with the control diet,supplementation with Enzyme A significantly decreased ileum lesion scoring at 16 d of age(P<0.05);supplementation with Enzyme B or Enzyme C showed positive effects on ileal amylopectin and total starch digestibility(P<0.05);Broilers fed with a diet supplemented with Enzyme D had a tendency to decrease body weight gain at 23 d.Enzyme E supplementation improved lesion scoring of jejunum and ileum at 16 d(P<0.05),and increased ileal amylopectin or total starch digestibility at 23 d(P<0.05).Supplementation of enzymes changed cecal microbiota diversity.High numbers of Campylobacter,Helicobacter and Butyricicoccus,Anaerostipes and Bifidobacterium,Sutterella and Odoribacter were the main genera detected in supplementations with Enzymes B,C,D,and E respectively.Conclusions:Supplementation with amylase combined with glucoamylase or protease showed a beneficial effect on starch digestibility and intestinal microbiota diversity,and increased growth of broilers fed with newly harvested corn. 展开更多
关键词 AMYLASE Broiler GLUCOAMYLASE Microbiota DIVERSITY NEWLY harvested CORN PROTEASE
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Newly Discovered Ca.163 Ma OIB-Type Diabase Dike from the Shiquanhe Ophiolites,Western Tibet 预览
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作者 LI Chenwei LI Zhijun +1 位作者 CAO Hui ZENG Min 《地质学报:英文版》 SCIE CAS CSCD 2018年第6期2443-2444,共2页
Objective The Shiquanhe ophiolite is an important tectonic belt in western Tibet.It has been debated whether the Shiquanhe ophiolite represents an allochthonous nappe derived from the Bangong-Nujiang suture zone to th... Objective The Shiquanhe ophiolite is an important tectonic belt in western Tibet.It has been debated whether the Shiquanhe ophiolite represents an allochthonous nappe derived from the Bangong-Nujiang suture zone to the north or the autochthonous remnants of a different oceanic crust (e.g.,Wu Zhenhan et al.,2016).Geochemical and geochronological studies of ophiolitic components are critical to understand evolutionary history of the Shiquanhe ophiolite and to resolve the controversy.This paper reports,for the first time,the late Middle Jurassic oceanic island basalt-type (OIB-type)diabase dike in the Shiquanhe ophiolite.The diabase is an important supplement to the knowledge of the petrologic assemblage of the Shiquanhe ophiolite and provides constraints on its evolutionary history. 展开更多
关键词 NEWLY Discovered
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Effect of liraglutide combined with basal insulin on blood glucose control, lipid metabolism and oxidative stress in patients with newly diagnosed type 2 diabetes mellitus complicated by obesity
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作者 Fei-Fei He Min-Xi Song +2 位作者 Lin Xu Rui-Bo Jia Wei Zhang 《海南医科大学学报(英文版)》 2018年第2期32-35,共4页
Objective:To investigate the effect of liraglutide combined with basal insulin on blood glucose control, lipid metabolism and oxidative stress in patients with newly diagnosed type 2 diabetes mellitus complicated by o... Objective:To investigate the effect of liraglutide combined with basal insulin on blood glucose control, lipid metabolism and oxidative stress in patients with newly diagnosed type 2 diabetes mellitus complicated by obesity.Methods: A total of 58 patients with newly diagnosed type 2 diabetes mellitus complicated by obesity who were diagnosed and treated in Xi'an No. 4 Hospital between February 2017 and August 2017 were divided into the control group (n=29) who received basal insulin therapy and the liraglutide group (n=29) who received liraglutide combined with basal insulin therapy according to random number table. The differences in the levels of glycolipid metabolism indexes and the contents of oxidative stress indexes were compared between the two groups before and after treatment.Results: Before treatment, the differences in the levels of glycolipid metabolism indexes in peripheral blood and the contents of oxidative stress indexes in serum were not statistically significant between the two groups. After 1 month of treatment, glucose metabolism indexes FBG and HOMA-IR levels in peripheral blood of liraglutide group were lower than those of control group;lipid metabolism indexes TC, TG, ApoB levels in peripheral blood were lower than those of control group, ApoA1 level was higher than those of control group;serum oxidation indexes MDA and LHP contents were lower than those of control group whereas anti-oxidation indexes GSH-Px and T-AOC contents were higher than those of control group.Conclusion: Liraglutide combined with basal insulin therapy can further control the glucolipid metabolism levels and inhibit the systemic oxidative stress response in patients with newly diagnosed type 2 diabetes mellitus complicated by obesity. 展开更多
关键词 NEWLY diagnosed type 2 diabetes MELLITUS LIRAGLUTIDE BASAL insulin Glucose METABOLISM Blood lipid METABOLISM Oxidative stress
新护士生涯适应力对其转型冲击的影响 被引量:10
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作者 罗兰 刘思维 +1 位作者 陈阳广 吴艳平 《中华现代护理杂志》 2016年第21期2971-2974,共4页
目的:探讨新护士生涯适应力对其转型冲击的影响。方法采用《生涯适应力量表》及《新护士转型冲击量表》对湖南省6家三级甲等医院223名新护士进行问卷调查,了解新护士生涯适应力及转型冲击的现状,分析两者之间的关系。结果在新护士生... 目的:探讨新护士生涯适应力对其转型冲击的影响。方法采用《生涯适应力量表》及《新护士转型冲击量表》对湖南省6家三级甲等医院223名新护士进行问卷调查,了解新护士生涯适应力及转型冲击的现状,分析两者之间的关系。结果在新护士生涯适应力中,生涯信心维度均分最高为(3.61±0.53)分,生涯控制维度均分最低为(3.29±0.74)分;而转型冲击中,身体维度均分最高为(3.72±0.84)分,社会文化与发展维度均分最低为(3.24±0.76)分。进一步研究发现,新护士生涯适应力各维度与转型冲击各维度得分呈负相关(r值分别为-0.440,-0.224,-0.258,-0.238;P〈0.05)。多元逐步回归分析显示,新护士生涯关注、生涯控制、生涯好奇、生涯信心为转型冲击的影响因素。结论医院管理者尤其要注重关注新护士的生涯关注力和生涯控制力,采取针对性措施提高新护士生涯适应力水平,使其顺利完成角色转变,稳定护理队伍,进一步提高医院护理质量。 展开更多
关键词 新护士 生涯适应力 转型冲击 NEWLY graduated nurses(NGRNs)
新建本科院校创建创业型大学策略研究 预览
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作者 贾宝栋 《湖南农机:学术版》 2013年第6期278-278,280共2页
新建本科院校随着高等教育的发展逐步建立和发展起来,面对新的国内外教育形势和复杂的组织内外环境,面对众多历史悠久的原有本科院校和高职高专院校的发展压力,新建本科院校如何结合自身特点科学合理的发展是亟需解决的问题。文章从新... 新建本科院校随着高等教育的发展逐步建立和发展起来,面对新的国内外教育形势和复杂的组织内外环境,面对众多历史悠久的原有本科院校和高职高专院校的发展压力,新建本科院校如何结合自身特点科学合理的发展是亟需解决的问题。文章从新建本科院校的特点出发,运用SWOT分析法全面分析了新建本科院校在发展过程中的优势、劣势、机会和威胁,进而在此基础上提出了建设创业型大学的发展目标并提出了具体的发展策略。 展开更多
关键词 新建本科院校 创业型大学 策略
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新兴世界知名高校的发展机制及其启示 预览
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作者 刘自团 《研究生教育研究》 CSSCI 2011年第6期 85-90,共6页
对应于传统的老牌院校,新兴世界知名高校特指"二战"以后建立或振兴起来、在短时间内赢得世界声誉的众多年轻院校。前沿性办学理念、特色型定位、创新型制度、国际化平台、与产业界的深度合作是这些新兴高校迅速崛起的共同经验。新兴... 对应于传统的老牌院校,新兴世界知名高校特指"二战"以后建立或振兴起来、在短时间内赢得世界声誉的众多年轻院校。前沿性办学理念、特色型定位、创新型制度、国际化平台、与产业界的深度合作是这些新兴高校迅速崛起的共同经验。新兴世界知名高校的发展历程对我国建设世界一流大学的启示是:要发挥比较优势,利用后发优势,创新发展机制。 展开更多
关键词 新兴 世界知名高校 发展机制
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地方新建本科院校体育教育特色专业建设理论探索 预览 被引量:1
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作者 余学好 屈杰 张春合 《怀化学院学报》 2011年第5期 89-91,共3页
基于地方新建本科院校特色专业建设和核心竞争力分析的背景,对湖南省部分高校体育教育专业特色建设的问题进行分析和研究,结果显示,新建地方本科院校的体育教育特色专业建设存在着一定的问题,主要表现在:专业口径较窄、专业类型单一化... 基于地方新建本科院校特色专业建设和核心竞争力分析的背景,对湖南省部分高校体育教育专业特色建设的问题进行分析和研究,结果显示,新建地方本科院校的体育教育特色专业建设存在着一定的问题,主要表现在:专业口径较窄、专业类型单一化,课程建设与专业建设没有协调发展,实训实习基地建设滞后等问题.因此,新建地方本科院校应深入分析特色专业内涵的基础上,根据特色专业的建设原则,以优化课程体系、加强实训、实践基地建设核心,进一步培育专业办学特色,提高办学质量,适应社会经济发展的需要,通过内涵创新来提升建设特色专业. 展开更多
关键词 新建 特色专业 体育教育 建设
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浅议黄土地区新建公路运营初期养护措施 预览
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作者 王玲转 《山西交通科技》 2011年第3期 3-5,共3页
论述了新改建公路在试运营期内,土方路基及排水构造物易发生的病害、发生病害的主要原因及防治措施。
关键词 黄土 地区 新建 公路 养护 措施
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新升工程应用型本科院校教师绩效考评体系的构建 预览
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作者 林晓艳 《成都大学学报:教育科学版》 2008年第1期 14-16,共3页
随着高等教育的发展,从20世纪90年代开始,有部分高职高专院校陆续升格为本科院校。文章以福建A学院为案例,分析新升的工程应用型本科院校,如何构建适合自身需要的教师绩效考评体系。
关键词 新升 工程应用 绩效
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初诊类风湿关节炎患者血清25羟维生素D水平与病情严重程度的相关性分析 预览
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作者 任云丽 王雪琴 《中国医学前沿杂志(电子版)》 2020年第1期125-128,共4页
目的分析初诊类风湿关节炎(rheumatoid arthritis,RA)患者血清25羟维生素D[25-hydroxyvitamin D,25(OH)D]水平与病情严重程度的相关性。方法回顾性分析南通市第一人民医院2016年1月至2018年12月收治的200例初诊RA患者的临床资料,并将其... 目的分析初诊类风湿关节炎(rheumatoid arthritis,RA)患者血清25羟维生素D[25-hydroxyvitamin D,25(OH)D]水平与病情严重程度的相关性。方法回顾性分析南通市第一人民医院2016年1月至2018年12月收治的200例初诊RA患者的临床资料,并将其纳入初诊RA组;将同期南通市第一人民医院100例健康体检者纳入健康对照组,比较两组研究对象25(OH)D水平。分别按照28个关节疾病活动度评分(disease activity score 28-joint count,DAS28)、骨密度、有无器官/系统受累、女性患者是否绝经和病程,对初诊RA组患者再次分组,并比较不同亚组患者血清25(OH)D水平,分析初诊RA患者血清25(OH)D水平与疾病活动度、骨密度、器官/系统受累情况、绝经情况和病程间的相关性。结果不同疾病活动度、不同骨密度、有无器官/系统受累、绝经与未绝经、不同病程的初诊RA患者血清25(OH)D水平比较差异均具有统计学意义(均P<0.05)。初诊RA患者血清25(OH)D水平与疾病活动度、绝经、RA病程均呈负相关(均P<0.05),与骨密度呈正相关(P<0.05),与器官/系统受累无明显相关性(P>0.05)。结论随着RA病情进展,患者血清25(OH)D水平呈下降趋势,可将血清25(OH)D作为评估RA病情严重程度的指标。 展开更多
关键词 类风湿关节炎 初诊 外周血 25羟维生素D 严重程度 相关性
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