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Different protein expression patterns in rat spinal nerves during wallerian degeneration assessed using isobaric tags for relative and absolute quantitation proteomics profiling 预览
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作者 Shuai Wei Xue-Zhen Liang +12 位作者 Qian Hu Wei-Shan Wang Wen-Jing Xu Xiao-Qing Cheng Jiang Peng Quan-Yi Guo Shu-Yun Liu Wen Jiang Xiao Ding Gong-Hai Han Ping Liu Chen-Hui Shi Yu Wang 《中国神经再生研究:英文版》 SCIE CAS CSCD 2020年第2期315-323,共9页
Sensory and motor nerve fibers of peripheral nerves have different anatomies and regeneration functions after injury. To gain a clear understanding of the biological processes behind these differences, we used a label... Sensory and motor nerve fibers of peripheral nerves have different anatomies and regeneration functions after injury. To gain a clear understanding of the biological processes behind these differences, we used a labeling technique termed isobaric tags for relative and absolute quantitation to investigate the protein profiles of spinal nerve tissues from Sprague-Dawley rats. In response to Wallerian degeneration, a total of 626 proteins were screened in sensory nerves, of which 368 were upregulated and 258 were downregulated. In addition, 637 proteins were screened in motor nerves, of which 372 were upregulated and 265 were downregulated. All identified proteins were analyzed using the Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis of bioinformatics, and the presence of several key proteins closely related to Wallerian degeneration were tested and verified using quantitative real-time polymerase chain reaction analyses. The differentially expressed proteins only identified in the sensory nerves were mainly relevant to various biological processes that included cell-cell adhesion, carbohydrate metabolic processes and cell adhesion, whereas differentially expressed proteins only identified in the motor nerves were mainly relevant to biological processes associated with the glycolytic process, cell redox homeostasis, and protein folding. In the aspect of the cellular component, the differentially expressed proteins in the sensory and motor nerves were commonly related to extracellular exosomes, the myelin sheath, and focal adhesion. According to the Kyoto Encyclopedia of Genes and Genomes, the differentially expressed proteins identified are primarily related to various types of metabolic pathways. In conclusion, the present study screened differentially expressed proteins to reveal more about the differences and similarities between sensory and motor nerves during Wallerian degeneration. The present findings could provide a reference point for a future investigation into the differences between s 展开更多
关键词 gene ontology Kyoto ENCYCLOPEDIA of Genes and Genomes ISOBARIC tags for RELATIVE and absolute quantitation motor NERVE PROTEOMICS sensory NERVE spinal NERVE Wallerian degeneration
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Bioinformatic identification of key candidate genes and pathways in axon regeneration after spinal cord injury in zebrafish 预览
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作者 Jia-He Li Zhong-Ju Shi +6 位作者 Yan Li Bin Pan Shi-Yang Yuan Lin-Lin Shi Yan Hao Fu-Jiang Cao Shi-Qing Feng 《中国神经再生研究:英文版》 SCIE CAS CSCD 2020年第1期103-111,共9页
Zebrafish and human genomes are highly homologous;however,despite this genomic similarity,adult zebrafish can achieve neuronal proliferation,regeneration and functional restoration within 6–8 weeks after spinal cord ... Zebrafish and human genomes are highly homologous;however,despite this genomic similarity,adult zebrafish can achieve neuronal proliferation,regeneration and functional restoration within 6–8 weeks after spinal cord injury,whereas humans cannot.To analyze differentially expressed zebrafish genes between axon-regenerated neurons and axon-non-regenerated neurons after spinal cord injury,and to explore the key genes and pathways of axonal regeneration after spinal cord injury,microarray GSE56842 was analyzed using the online tool,GEO2R,in the Gene Expression Omnibus database.Gene ontology and protein-protein interaction networks were used to analyze the identified differentially expressed genes.Finally,we screened for genes and pathways that may play a role in spinal cord injury repair in zebrafish and mammals.A total of 636 differentially expressed genes were obtained,including 255 up-regulated and 381 down-regulated differentially expressed genes in axon-regenerated neurons.Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment results were also obtained.A protein-protein interaction network contained 480 node genes and 1976 node connections.We also obtained the 10 hub genes with the highest correlation and the two modules with the highest score.The results showed that spectrin may promote axonal regeneration after spinal cord injury in zebrafish.Transforming growth factor beta signaling may inhibit repair after spinal cord injury in zebrafish.Focal adhesion or tight junctions may play an important role in the migration and proliferation of some cells,such as Schwann cells or neural progenitor cells,after spinal cord injury in zebrafish.Bioinformatic analysis identified key candidate genes and pathways in axonal regeneration after spinal cord injury in zebrafish,providing targets for treatment of spinal cord injury in mammals. 展开更多
关键词 axonal REGENERATION differentially expressed GENES focal ADHESIONS Gene Ontology Kyoto Encyclopedia of GENES and Genomes neural REGENERATION protein-protein interaction network SIGNALING PATHWAY SPECTRIN tight junctions transforming growth factor beta Wnt SIGNALING PATHWAY
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Protein microarray analysis of cytokine expression changes in distal stumps after sciatic nerve transection 预览
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作者 Xiao-Qing Cheng Xue-Zhen Liang +9 位作者 Shuai Wei Xiao Ding Gong-Hai Han Ping Liu Xun Sun Qi Quan He Tang Qing Zhao Ai-Jia Shang Jiang Peng 《中国神经再生研究:英文版》 SCIE CAS CSCD 2020年第3期503-511,共9页
A large number of chemokines,cytokines,other trophic factors and the extracellular matrix molecules form a favorable microenvironment for peripheral nerve regeneration.This microenvironment is one of the major factors... A large number of chemokines,cytokines,other trophic factors and the extracellular matrix molecules form a favorable microenvironment for peripheral nerve regeneration.This microenvironment is one of the major factors for regenerative success.Therefore,it is important to investigate the key molecules and regulators affecting nerve regeneration after peripheral nerve injury.However,the identities of specific cytokines at various time points after sciatic nerve injury have not been determined.The study was performed by transecting the sciatic nerve to establish a model of peripheral nerve injury and to analyze,by protein microarray,the expression of different cytokines in the distal nerve after injury.Results showed a large number of cytokines were up-regulated at different time points post injury and several cytokines,e.g.,ciliary neurotrophic factor,were downregulated.The construction of a protein-protein interaction network was used to screen how the proteins interacted with differentially expressed cytokines.Kyoto Encyclopedia of Genes and Genomes pathway and Gene ontology analyses indicated that the differentially expressed cytokines were significantly associated with chemokine signaling pathways,Janus kinase/signal transducers and activators of transcription,phosphoinositide 3-kinase/protein kinase B,and notch signaling pathway.The cytokines involved in inflammation,immune response and cell chemotaxis were up-regulated initially and the cytokines involved in neuronal apoptotic processes,cell-cell adhesion,and cell proliferation were up-regulated at 28 days after injury.Western blot analysis showed that the expression and changes of hepatocyte growth factor,glial cell line-derived neurotrophic factor and ciliary neurotrophic factor were consistent with the results of protein microarray analysis.The results provide a comprehensive understanding of changes in cytokine expression and changes in these cytokines and classical signaling pathways and biological functions during Wallerian degeneration,as well as a bas 展开更多
关键词 cytokines DISTAL stump gene ontology KYOTO ENCYCLOPEDIA of Genes and Genomes pathway peripheral nerve injury protein microarray PROTEIN-PROTEIN interaction network Wallerian degeneration
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什么是中国美学
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作者 彭锋 《中国高校社会科学》 CSSCI 北大核心 2019年第1期109-116,共8页
由于中国美学博大精深,研究者通常很难对它做出简要的概括,以致国外一些重要的百科全书缺乏“中国美学”条目。通过梳理几种有代表性的英文工具书中的“中国美学”条目并结合相关专家的研究,我们可以试着回答什么是中国美学这一问题。
关键词 中国美学 百科全书 苏源熙 稻田龟男 叶朗
Expression and significance of PAX8 gene in ovarian cancer based on Oncomine database Meta-analysis 预览
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作者 Kun Yan Hua Yan +3 位作者 Qin Zhou Min Wan Yanyan Ge Jin Lu 《肿瘤学与转化医学:英文版》 2019年第4期175-181,共7页
Objective Although great progress has been made in the diagnosis and treatment of ovarian cancer, this disease is still the leading cause of death due to female reproductive system tumors. It has been reported that th... Objective Although great progress has been made in the diagnosis and treatment of ovarian cancer, this disease is still the leading cause of death due to female reproductive system tumors. It has been reported that the paired box 8 (PAX8) gene is involved in the occurrence and development of a variety of human tumors. However, few researchers have investigated this phenomenon in detail. Methods Here, the BioGPS database was used to analyze the expression of the PAX8 gene in normal tissues. The Oncomine database was used to search for PAX8 gene information, and the findings were analyzed via a meta-analysis with regard to the significance of this gene in ovarian cancer. The Kaplan- Meier Plotter database was used to analyze the prognosis of patients with ovarian cancer. The Cancer Cell Line Encyclopedia (CCLE) was used only for obtaining cell line analysis data regarding the PAX8 gene. Results The relevant results of the BioGPS database analysis showed that PAX8 is not expressed or under-expressed in normal ovarian tissues. Oncomine data showed 454 different results;there were 417 study samples in total, with 9 results showing a significant statistical difference in PAX8 expression, 5 of which were related to high expression of PAX8 and 4 of which were related to low PAX8 expression. Cell line analysis data of the PAX8 gene obtained from CCLE showed high expression in ovarian cancer, which is consistent with the high expression of PAX8 in ovarian cancer research found using the Oncomine database. The Kaplan-Meier Plotter database showed that the expression level of PAX8 had a significant effect on the overall survival time of patients (P = 0.042). Compared with the low expression group, the overall survival time of ovarian cancer patients in the high expression group of PAX8 was significantly low (P < 0.05). Conclusion Through an in-depth study of the gene information of ovarian cancer-related genes using the gene chip data in the Oncomine database, it was concluded that PAX8 is highly expressed in ovarian cancer 展开更多
关键词 OVARIAN CANCER GENE paired box 8 CANCER cell line ENCYCLOPEDIA
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Bioinformatics analyses of differentially expressed genes associated with spinal cord injury:a microarray-based analysis in a mouse model 预览
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作者 Lei Guo Jing Lv +2 位作者 Yun-Fei Huang Ding-Jun Hao Ji-Jun Liu 《中国神经再生研究:英文版》 SCIE CAS CSCD 2019年第7期1262-1270,共9页
Gene spectrum analysis has shown that gene expression and signaling pathways change dramatically after spinal cord injury,which may affect the microenvironment of the damaged site.Microarray analysis provides a new op... Gene spectrum analysis has shown that gene expression and signaling pathways change dramatically after spinal cord injury,which may affect the microenvironment of the damaged site.Microarray analysis provides a new opportunity for investigating diagnosis,treatment,and prognosis of spinal cord injury.However,differentially expressed genes are not consistent among studies,and many key genes and signaling pathways have not yet been accurately studied.GSE5296 was retrieved from the Gene Expression Omnibus DataSet.Differentially expressed genes were obtained using R/Bioconductor software(expression changed at least two-fold;P<0.05).Database for Annotation,Visualization and Integrated Discovery was used for functional annotation of differentially expressed genes and Animal Transcription Factor Database for predicting potential transcription factors.The resulting transcription regulatory protein interaction network was mapped to screen representative genes and investigate their diagnostic and therapeutic value for disease.In total,this study identified 109 genes that were upregulated and 30 that were downregulated at 0.5,4,and 24 hours,and 3,7,and 28 days after spinal cord injury.The number of downregulated genes was smaller than the number of upregulated genes at each time point.Database for Annotation,Visualization and Integrated Discovery analysis found that many inflammation-related pathways were upregulated in injured spinal cord.Additionally,expression levels of these inflammation-related genes were maintained for at least 28 days.Moreover,399 regulation modes and 77 nodes were shown in the protein-protein interaction network of upregulated differentially expressed genes.Among the 10 upregulated differentially expressed genes with the highest degrees of distribution,six genes were transcription factors.Among these transcription factors,ATF3 showed the greatest change.ATF3 was upregulated within 30 minutes,and its expression levels remained high at 28 days after spinal cord injury.These key genes screened by bioinf 展开更多
关键词 nerve REGENERATION spinal cord injury differentially expressed GENES BIOINFORMATICS ANALYSES Database for Annotation Visualization and Integrated Discovery ANALYSIS inflammation Kyoto Encyclopedia of GENES and Genomes pathway MICROARRAY transcription factors neural REGENERATION
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《大数据百科全书》术语特点及收录与处理原则 预览
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作者 大数据战略重点实验室 基于大数据的城市科学研究北京市重点实验室 《中国科技术语》 2019年第2期58-62,共5页
大数据发展日新月异,新的应用需求和实践问题层出不穷,社会各界越来越重视大数据的基础研究。百科全书作为知识门类的概述性著作,是开展和推动基础研究的重要载体。作为大数据知识传播的工具,《大数据百科全书》不仅要有实用与新颖兼备... 大数据发展日新月异,新的应用需求和实践问题层出不穷,社会各界越来越重视大数据的基础研究。百科全书作为知识门类的概述性著作,是开展和推动基础研究的重要载体。作为大数据知识传播的工具,《大数据百科全书》不仅要有实用与新颖兼备的知识内容,并且还应具备准确严谨与通畅易懂的专业化语言文字表达。其中,术语是《大数据百科全书》不可或缺的有机组成部分,文章总结大数据领域的术语特点,并以此提出《大数据百科全书》术语方面的收录和处理原则。 展开更多
关键词 大数据 百科全书 术语
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Analysis of the autophagy gene expression profile of pancreatic cancer based on autophagy-related protein microtubule-associated protein 1A/1B-light chain 3 预览
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作者 Yan-Hui Yang Yu-Xiang Zhang +3 位作者 Yang Gui Jiang-Bo Liu Jun-Jun Sun Hua Fan 《世界胃肠病学杂志:英文版》 SCIE CAS 2019年第17期2086-2098,共13页
BACKGROUND Pancreatic cancer is a highly invasive malignant tumor. Expression levels of the autophagy-related protein microtubule-associated protein 1A/1B-light chain 3 (LC3) and perineural invasion (PNI) are closely ... BACKGROUND Pancreatic cancer is a highly invasive malignant tumor. Expression levels of the autophagy-related protein microtubule-associated protein 1A/1B-light chain 3 (LC3) and perineural invasion (PNI) are closely related to its occurrence and development. Our previous results showed that the high expression of LC3 was positively correlated with PNI in the patients with pancreatic cancer. In this study, we further searched for differential genes involved in autophagy of pancreatic cancer by gene expression profiling and analyzed their biological functions in pancreatic cancer, which provides a theoretical basis for elucidating the pathophysiological mechanism of autophagy in pancreatic cancer and PNI. AIM To identify differentially expressed genes involved in pancreatic cancer autophagy and explore the pathogenesis at the molecular level. METHODS Two sets of gene expression profiles of pancreatic cancer/normal tissue (GSE16515 and GSE15471) were collected from the Gene Expression Omnibus. Significance analysis of microarrays algorithm was used to screen differentially expressed genes related to pancreatic cancer. Gene Ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were used to analyze the functional enrichment of the differentially expressed genes. Protein interaction data containing only differentially expressed genes was downloaded from String database and screened. Module mining was carried out by Cytoscape software and ClusterOne plug-in. The interaction relationship between the modules was analyzed and the pivot nodes between the functional modules were determined according to the information of the functional modules and the data of reliable protein interaction network.RESULTS Based on the above two data sets of pancreatic tissue total gene expression, 6098 and 12928 differentially expressed genes were obtained by analysis of genes with higher phenotypic correlation. After extracting the intersection of the two differential gene sets, 4870 genes were determined 展开更多
关键词 Pancreatic cancer Autophagy-related PROTEIN microtubule-associated PROTEIN 1A/1B-light chain 3 Perineural invasion Gene Ontology ANALYSIS KYOTO ENCYCLOPEDIA of Genes and Genomes pathway ANALYSIS Ubiquitin C
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信息素质教育游戏网站内部迷你百科的设计 预览 被引量:1
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作者 王姣姣 吴建华 李静霞 《高校图书馆工作》 CSSCI 2018年第5期54-57,共4页
由于网络百科词条数量庞大且缺乏监管的特点, 人们在使用过程中往往面临着信息迷雾和信息过载的困扰.课题组为把课题研究产生的小游戏组织起来开放给大家使用, 建立了一个信息素质教育游戏网站《 信息素养修炼站》 .考虑到玩家在游戏过... 由于网络百科词条数量庞大且缺乏监管的特点, 人们在使用过程中往往面临着信息迷雾和信息过载的困扰.课题组为把课题研究产生的小游戏组织起来开放给大家使用, 建立了一个信息素质教育游戏网站《 信息素养修炼站》 .考虑到玩家在游戏过程中可能会碰到疑惑, 在网站内部设计了一个迷你百科, 方便玩家在需要的时候随时检索、 查阅词条.迷你百科发挥网络百科集中众人智慧的优势, 同时避免了其信息过载等问题.参考文献2 0 . 展开更多
关键词 信息素质教育 信息素养修炼 百科 知识组织与服务
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百科全书与启蒙运动
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作者 李鹃(译) 《伦理学术》 2018年第1期74-84,共11页
本文通过研究百科全书从17世纪的早期目录学模式到18世纪繁盛期的发展历史、对启蒙运动时期百科全书的特征予以了检视。其主要考察的百科全书包括英国的钱伯斯《百科全书》、法国的狄德罗《百科全书》和德国的策德勒《综合大词典》。流... 本文通过研究百科全书从17世纪的早期目录学模式到18世纪繁盛期的发展历史、对启蒙运动时期百科全书的特征予以了检视。其主要考察的百科全书包括英国的钱伯斯《百科全书》、法国的狄德罗《百科全书》和德国的策德勒《综合大词典》。流行观点认为启蒙运动时期的百科全书展示了知识的相互关联和内在秩序。作者则指出,尽管钱伯斯和狄德罗提出要对知识进行体系整理,但这一要求并未得到充分实现。而与此相反,对于策德勒《综合大词典》的编写者而言,首要的问题不是知识的秩序,而是知识的汇集和规模。 展开更多
关键词 百科全书 启蒙运动 钱伯斯 狄德罗 策德勒
数字人文的简明“百科”——评《走向数字人文:实践、训练与研究》 预览 被引量:1
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作者 钱国富 《图书馆论坛》 CSSCI 北大核心 2018年第7期12-15,23共5页
《走向数字人文:实践、训练与研究》一书从概念、实践、教育和研究等多视角考察了数字人文领域的相关概念和进展,是一本关于数字人文的简明"百科"。文章对该书的体例及内容进行全面评价,分析其对图书馆开展数字人文服务的参考意义。
关键词 数字人文 简明百科 图书馆 书评
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民間通書的民俗學價值 预览
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作者 彭恒禮 《中国俗文化研究》 2018年第2期65-76,共12页
民間通書是民衆計時擇吉使用的日常生活指導用書。除指示時間外,通書傳授的知識包括信仰、天文、曆法、地理、人生禮儀、風水、術數、應用寫作、數學、醫學、遊藝、文學、藝術等方面的內容。在公共教育體系不發達的古代,通書發揮着民間... 民間通書是民衆計時擇吉使用的日常生活指導用書。除指示時間外,通書傳授的知識包括信仰、天文、曆法、地理、人生禮儀、風水、術數、應用寫作、數學、醫學、遊藝、文學、藝術等方面的內容。在公共教育體系不發達的古代,通書發揮着民間教科書作用,指導規範民衆生活,因而對民俗學研究有很高的學術價值,是解釋古代民衆生活所以然的重要切入口。 展开更多
关键词 民間通書 民俗 百科全書 民俗教材
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《本草纲目》的艺术美 预览 被引量:1
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作者 韩进林 《黄冈职业技术学院学报》 2018年第4期7-11,共5页
千古人杰李时珍的《本草纲目》历经四百余年的实践检验,不仅仅是一部中华药学巨著、世界医学宝典,亦是一部百科全书。书中的花草虫鱼、瓜果菜蔬、土木金石等千余种植物、动物、矿物,通过李时珍的艺术再现,皆具灵性;千奇百怪的疑难顽疾,... 千古人杰李时珍的《本草纲目》历经四百余年的实践检验,不仅仅是一部中华药学巨著、世界医学宝典,亦是一部百科全书。书中的花草虫鱼、瓜果菜蔬、土木金石等千余种植物、动物、矿物,通过李时珍的艺术再现,皆具灵性;千奇百怪的疑难顽疾,变化万千的诸症杂病,近乎奇葩的四诊八纲等枯燥的医学、藏象学、病理学等常识,在李时珍笔下显现出鲜明之活力。这就是文学艺术的魅力所在。《本草纲目》中的艺术美不胜枚举。 展开更多
关键词 本草纲目 医学宝典 百科全书 艺术美
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明代类书存佚考论——以《中国古籍总目》著录为例
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作者 朱仙林 《图书馆杂志》 CSSCI 北大核心 2018年第2期101-111,共11页
类书作为一种较为特殊的著述体裁,在历史上曾产生过重要影响。明代作为类书编纂的重要历史时期,编纂类书的总数有多少、存佚情況如何,实有必要加以认真梳理。以现今著录明代类书最多的《中国古籍总目》为例,著录有439种。但据考察所知,... 类书作为一种较为特殊的著述体裁,在历史上曾产生过重要影响。明代作为类书编纂的重要历史时期,编纂类书的总数有多少、存佚情況如何,实有必要加以认真梳理。以现今著录明代类书最多的《中国古籍总目》为例,著录有439种。但据考察所知,其实明代曾先后编纂出类书665种,其中46种已亡佚不存,另有180余种至今尚存而《总目》未著录。 展开更多
关键词 明代 类书 《中国古籍总目》 存佚
联合国教科文组织《管道工程》百科全书的编著及内容概述 被引量:1
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作者 程玉峰 《油气储运》 北大核心 2017年第10期1107-1112,共6页
随着全球油气管道建设的蓬勃发展,“管道工程”作为一门新兴交叉学科,已经形成了内容丰富且独具特色的知识体系。2006年,联合国教科文组织《生命支持系统》大百科全书(Encyclopedia of Life Support Systems,EOLSS)编辑部邀请卡尔加... 随着全球油气管道建设的蓬勃发展,“管道工程”作为一门新兴交叉学科,已经形成了内容丰富且独具特色的知识体系。2006年,联合国教科文组织《生命支持系统》大百科全书(Encyclopedia of Life Support Systems,EOLSS)编辑部邀请卡尔加里大学终身教授、管道工程领域加拿大首席科学家、美国腐蚀工程师协会会士程玉峰博士担任主编,组织国际知名专家撰写了全球首部《管道工程》百科全书。全书包括10本系列丛书,全方位介绍了管道工程各个技术领域的相关知识,对于管道建设、国家政策制定、工业标准发展与研发指导等,具有重要意义。 展开更多
关键词 管道工程 百科全书 编著 内容概述
博物学的南宋图景:以《古今合璧事类备要》为中心的考察 预览
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作者 温志拔 《渭南师范学院学报:综合版》 2017年第3期53-57,共5页
南宋类书中的博物学知识,相比中古时期博物学专书以及北宋以前类书,尽管奇闻异物色彩仍在,却出现了更为突出的客观化、科学化的转向。这一转向可以从南宋类书《事类备要》抄录文献种类、文字内容选择,以及少量编纂者评论中得以体现。宋... 南宋类书中的博物学知识,相比中古时期博物学专书以及北宋以前类书,尽管奇闻异物色彩仍在,却出现了更为突出的客观化、科学化的转向。这一转向可以从南宋类书《事类备要》抄录文献种类、文字内容选择,以及少量编纂者评论中得以体现。宋代儒学复兴所带来的政治、学术和博物自身发展变化,是这一转向的重要原因。南宋类书所展现的宋代博物学,与中古时期博物学主要受本土神仙方术和外来佛教影响,以及明清时代博物学主要受西学科学知识影响不同,主要是儒学宋学阶段所具有的人文及理性精神影响的结果。 展开更多
关键词 南宋 类书 《事类备要》 博物学
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百科全书的整体性、系统化与条目审读 预览 被引量:1
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作者 李静 《编辑之友》 CSSCI 北大核心 2017年第6期78-82,共5页
百科全书的编纂从对百科全书进行整体设计开始,将百科全书编纂成具整体性的系统是设计的目标。编辑对条目的审读工作是实现其设计目标的关键。编辑要通过有效审读,更好地实现百科全书的整体性和系统化;同时在百科全书整体性和系统化... 百科全书的编纂从对百科全书进行整体设计开始,将百科全书编纂成具整体性的系统是设计的目标。编辑对条目的审读工作是实现其设计目标的关键。编辑要通过有效审读,更好地实现百科全书的整体性和系统化;同时在百科全书整体性和系统化的要求下,去发现、解决条目内容中的问题。这两个方面,不可或缺,不可偏废。 展开更多
关键词 百科全书 条目 编辑 审读 整体性 系统化
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“四库学”研究视域下《四库全书学典》价值探析
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作者 周勇军 《四库学》 2017年第2期36-41,共6页
民国时期出版的《四库全书学典》是一部对《四库全书》进行全面性介绍的知识类书籍,具有较高的文献价值与学术价值。通过考察《四库全书学典》的编纂缘起、内容体例和出版意义,有助于展现《四库全书学典》的价值所在。随着'四库学&#... 民国时期出版的《四库全书学典》是一部对《四库全书》进行全面性介绍的知识类书籍,具有较高的文献价值与学术价值。通过考察《四库全书学典》的编纂缘起、内容体例和出版意义,有助于展现《四库全书学典》的价值所在。随着'四库学'研究的不断推进,重新审视并挖掘《四库全书学典》的价值显得尤为重要。 展开更多
关键词 杨家骆 学典 《四库全书》 《四库全书学典》
维基百科国内外研究综述与展望 预览 被引量:1
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作者 付巧 杨海英 《新世纪图书馆》 CSSCI 2016年第2期85-90,共6页
基于对国内外维基百科研究文献的搜集与分析,论文从维基百科(技术)评介、内容研究、志愿者及其组织方式研究和维基百科(技术)应用研究等方面总结国外维基百科研究成果;从维基百科引介、信息组织及条目质量控制方式研究、维基百科(... 基于对国内外维基百科研究文献的搜集与分析,论文从维基百科(技术)评介、内容研究、志愿者及其组织方式研究和维基百科(技术)应用研究等方面总结国外维基百科研究成果;从维基百科引介、信息组织及条目质量控制方式研究、维基百科(技术)应用研究和维基百科与中国网络百科全书研究等方面总结国内维基百科研究成果,分析发现国内外研究在研究视角、研究内容与研究方法上存在相同之处与差距,指出国内外研究的不足,并对今后的研究提出了几点建议。 展开更多
关键词 维基百科 百科全书 中国网络百科全书 信息组织
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从中国大百科全书第一版文物卷到第三版文物卷的曲折历程
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作者 李晓东 《中国文物科学研究》 2016年第4期1-7,共7页
本文分为四部分:一、中国大百科全书第一版文物卷编纂启动、争议、出版,二、中国大百科全书第二版文物被忽略,三、中国大百科全书第三版文物卷的列入,思考之要点。
关键词 大百科全书 第一版 第二版 第三版 文物卷 学科建设