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Development and prospects of cervical laminoplasty
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作者 Wen-Xuan Wang Bin Zhao +1 位作者 Xiao-Feng Zhao Shao-Wei Wang 《海南医科大学学报(英文版)》 2019年第5期73-76,共4页
Cervical laminoplasty surgery is an alternative to laminectomy. It can increase the space of the spinal cord available by raising the lamina, and achieve the indirect decompression effect to treat cervical spondylosis... Cervical laminoplasty surgery is an alternative to laminectomy. It can increase the space of the spinal cord available by raising the lamina, and achieve the indirect decompression effect to treat cervical spondylosis. Various techniques of laminoplasty have since been developed after two prototype techniques: Hirabayashi's open-door laminoplasty and Kurokawa's double-door laminoplasty. Several studies report superior biomechanical stability of the cervical spine after laminoplasty compared with laminectomy. Recent development in laminoplasty is preservation of muscle attachment, which enabled dynamic and static stabilization of the cervical spine by neck extensor muscles. After treatment with new laminoplasty techniques with active postoperative neck muscle exercises, postoperative instability, kyphosis, axial neck pain, and loss of ROM become minimal. The development,complications and future trends of cervical laminoplasty are summarized below. 展开更多
关键词 CERVICAL CERVICAL spondylotic MYELOPATHY LAMINOPLASTY CERVICAL STABILITY
Giant Cervical Kystic Lymphangioma in Children: Surgical Management of a Case 预览
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作者 Youssouf Sidibé Abdoulaye Kanté +13 位作者 Amady Coulibaly Rokia Koné Mamadou Koné Fatoumata Léonie Franç ois Diakité Drissa Ouattara Abdoul Wahab Haidara Boubacar Sanogo Sidiki Dao N’faly Konate Kadiatou Singaré Doumbia Samba Karim Timbo Mohamed Keita Alhousseini Ag Mohamed 《耳鼻喉(英文)》 2019年第1期1-6,共6页
Introduction: Cervical cystic lymphangiomas are rare benign dysembryoplastic tumors of lymphatic origin. Its severity in the child is due on one hand to their fast evolution and the compression of the way aerodigestiv... Introduction: Cervical cystic lymphangiomas are rare benign dysembryoplastic tumors of lymphatic origin. Its severity in the child is due on one hand to their fast evolution and the compression of the way aerodigestive and on the other hand, by the classical difficulty of their excision. The purpose of this work was to report a case of giant cervical cystic lymphangioma in a child to discuss the difficulties associated with its management in our context. Observation: This was a 3-year-old female child who was admitted to the ENT department of CHU “Luxembourg” for right lateral cervical swelling. The clinical examination had noted a large anterior-latero cervical swelling of soft, renitent, painless palpation, movable in relation to the superficial and deep plane, measuring about 20 cm × 17 cm, the skin was healthy. It wasn’t particularity to the rest of the physical examination. The diagnosis of giant cervical cystic lymphangioma was discussed. Thorough excision of the swelling by right lateral cervicotomy was performed. Anatomopathological examination of the operative specimen confirmed the diagnosis. The postoperative course was simple and the evolution was favorable. Conclusion: Cervical cystic lymphangiomas are rare. Their management involves surgery, with short and long-term post-operative outcomes are often excellent. 展开更多
关键词 Kystic LYMPHANGIOMA CERVICAL CHILD BAMAKO
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一种新型颈椎前路可固定式钛笼三维有限元模型的建立 预览
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作者 徐成 张超 +1 位作者 巨圆圆 李超 《中国医学装备》 2019年第6期8-11,共4页
目的:基于人体C4~C6节段椎体次全切除术(ACCF),应用一种新型颈椎前路可固定式钛笼,建立三维有限元仿真分析模型。方法:获得健康男性颈椎薄层CT图像,利用Mimics软件进行颈椎骨性结构三维重建,导入3-Matics软件进行模型修补,补充结构,利用... 目的:基于人体C4~C6节段椎体次全切除术(ACCF),应用一种新型颈椎前路可固定式钛笼,建立三维有限元仿真分析模型。方法:获得健康男性颈椎薄层CT图像,利用Mimics软件进行颈椎骨性结构三维重建,导入3-Matics软件进行模型修补,补充结构,利用Ansys软件完成有限元模型的建立。计算正常颈椎模型各节段的运动范围,与文献数据进行对比以验证其有效性,并模拟颈椎椎体次全切除术式,将新型钛笼模型添加到减压区,建立C5节段ACCF钛笼固定有限元模型。结果:建立的正常颈椎C4~C6节段钛笼三维有限元模型各节段的运动范围与既往文献研究结果近似;对ACCF术式有限元模型进行静态力学分析,获得钛笼与相邻椎体表面等效应力值。结论:新型钛笼三维有限元模型的设计,对于降低钛笼沉降可起到积极作用,该模型与实体标本具有较好的相似性,可用于术式模拟和后续实验研究,并为颈椎内固定器械的设计提供技术支持。 展开更多
关键词 颈椎 固定 钛笼 有限元分析 颈椎椎体次全切除术
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Distribution of high-risk human papillomavirus genotype prevalence and attribution to cervical precancerous lesions in rural North China 预览
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作者 Shuang Zhao Xuelian Zhao +5 位作者 Shangying Hu Jessica Lu Xianzhi Duan Xun Zhang Feng Chen Fanghui Zhao 《中国癌症研究:英文版》 SCIE CAS CSCD 2019年第4期663-672,共10页
Objective: Precise prevention is more desired for cervical cancer due to the huge population, high prevalence of human papillomavirus(HPV) infection in China and the vision of screen-and-treat strategies in low-and mi... Objective: Precise prevention is more desired for cervical cancer due to the huge population, high prevalence of human papillomavirus(HPV) infection in China and the vision of screen-and-treat strategies in low-and middleincome countries(LMICs). Considerations of combining type-specific prevalence and attribution proportion to high-grade cervical intraepithelial neoplasia are informative to more precise and effective region-specific cervical cancer prevention and control programs. The aim of the current study was to determine the genotype distribution of HPV and attribution to cervical precancerous lesions among women from rural areas in North China.Methods: A total of 9,526 women participated in the cervical cancer screening project in rural China. The samples of women who tested positive for HPV were retested with a polymerase chain reaction(PCR)-based HPV genotyping test. The attribution proportion of specific high-risk human papillomavirus(HR-HPV) types for different grades of cervical lesions was calculated by using the type contribution weighting method.Results: A total of 22.2%(2,112/9,526) of women were HR-HPV positive and HPV52(21.7%) was the most common HR-HPV genotype, followed by HPV58(18.2%), HPV53(18.2%) and HPV16(16.2%). The top three genotypes detected in HR-HPV-positive cervical intraepithelial neoplasia(CIN)1 were HPV16(36.7%), HPV58(20.4%), HPV56(15.3%). Among CIN2+, the most frequent genotypes were HPV16(75.6%), HPV52(17.8%),HPV58(16.7%). HPV16, 56, 58, 53, 52, 59, 68, and 18 combined were attributed to 84.17% of all CIN1 lesions,and HPV16, 58, and 52 combined were attributed to 86.98% of all CIN2+ lesions.Conclusions: The prevalence of HR-HPV infection among women from rural areas in North China was high and HPV16, HPV58, HPV52 had paramount attributable fraction in CIN2+. Type-specific HPV prevalence and attribution proportion to cervical precancerous lesions should be taken into consideration in the development of vaccines and strategy for screening in this population. 展开更多
关键词 Human PAPILLOMAVIRUS CERVICAL intraepithelial NEOPLASIA GENOTYPE DISTRIBUTION ATTRIBUTION proportion CERVICAL cancer
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Curative Effects of Warming Needle Moxibustion Combined with Manipulation Massage on Cervical Spondylotic Vertebral Arteriopathy and Its Influence on the Cerebral Blood Flow Parameters and Cervical Vertebral Function 预览
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作者 翟炳生 《世界中西医结合杂志(英文)》 2019年第3期17-23,共7页
OBJECTIVE: To explore the curative effects of warming needle moxibustion combined with manipulation massage on cervical spondylotic vertebral arteriopathy and its influence on the cerebral blood flow and cervical vert... OBJECTIVE: To explore the curative effects of warming needle moxibustion combined with manipulation massage on cervical spondylotic vertebral arteriopathy and its influence on the cerebral blood flow and cervical vertebra function. METHODS: A total of 84 patients with cervical spondylotic vertebral arteriopathy admitted to our hospital from February 2016 to June 2017 were selected, and all patients were divided into an observation group (n=42) and a control group (n=42) according to the random number table method. The patients in the control group were given conventional western treatment, and the patients in the observation group were treated with warming needle moxibustion combined with manipulation massage on the basis of the control group. After 4 weeks of treatment, the changes of main clinical symptoms (vertigo, headache, neck and shoulder pain, tinnitus), cervical function (clinical symptoms, clinical examination, daily life action) and cerebral blood flow parameters (average blood flow velocity of left vertebral artery, right vertebral artery and basilar artery) of the 2 groups were observed, and the clinical efficacy of the 2 groups were statistically analyzed. RESULTS: The scores of vertigo, headache, neck and shoulder pain and tinnitus in the 2 groups were all significantly lower than before treatment (P < 0.05), and the clinical symptom scores in the observation group were significantly lower after treatment (P < 0.05);After treatment, the scores of clinical symptoms, clinical examination and daily life action in the 2 groups were significantly higher than those before treatment (P < 0.05), and the increase of cervical vertebral function score in the observation group was better than that in the control group (P < 0.05);The mean blood flow velocity of the left vertebral artery, right vertebral artery and the basilar artery in the 2 groups after treatment were significantly higher than before treatment (P < 0.05), and the increase of the above cerebral blood flow parameters in the observation group wer 展开更多
关键词 CERVICAL spondylotic VERTEBRAL ARTERIOPATHY WARMING needle MOXIBUSTION Manipulation MASSAGE Cerebral blood flow parameters CERVICAL spine function
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Expression and clinical significance of Klotho and Beclin1 in cervical squamous carcinoma
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作者 Wei He Qian-Chuan Ren 《海南医科大学学报(英文版)》 2019年第8期12-17,共6页
Objective:To detect the expression of klotho and beclin1 protein in chronic cervicitis, low grade squamous intraepithelial lesion (LSIL) group, high grade squamous intraepithelial lesion (HSIL) group and cervical squa... Objective:To detect the expression of klotho and beclin1 protein in chronic cervicitis, low grade squamous intraepithelial lesion (LSIL) group, high grade squamous intraepithelial lesion (HSIL) group and cervical squamous cell carcinoma (SCC) group.Methods:Immunohistochemical technique (Envision) was used to detect the expression of Klotho and Beclin1 proteins in each study group. The correlation between the expression of the above two proteins and the pathological features of SCC and the expression of the two proteins in SCC were analyzed.Results: The positive expression rates of Klotho protein in chronic cervicitis group, LSIL group, HSIL group and SCC group were 95%, 92.86%, 65.38%, 27.90%, respectively. The positive rates of Beclin1 protein in chronic cervicitis group, LSIL group, HSIL group were 25.0%, 28.57%, 38.46% and 74.42%, respectively. The differences were statistically significant. The expression of Klotho and Beclin1 in SCC was correlated with the degree of tumor differentiation, but not with the age, figo stage, lymph node metastasis, tumor size, depth of invasion and vessel invasion, but not with the age of the patient, tumor figo stage, lymph node metastasis, tumor size, depth of invasion and vessel invasion. There was no correlation between the expression of klotho and beclin1 in SCC tissues.Conclusion: The abnormal expression of klotho and beclin1 may be related to the development, invasion and metastasis of cervical squamous cell carcinoma. 展开更多
关键词 KLOTHO BECLIN1 CERVICAL SQUAMOUS cell CARCINOMA CERVICAL intraepithelial LESION
Establishment and verification of a surgical prognostic model for cervical spinal cord injury without radiological abnormality 预览
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作者 Jie Wang Shuai Guo +2 位作者 Xuan Cai Jia-Wei Xu Hao-Peng Li 《中国神经再生研究:英文版》 SCIE CAS CSCD 2019年第4期713-720,共8页
Some studies have suggested that early surgical treatment can effectively improve the prognosis of cervical spinal cord injury without radiological abnormality,but no research has focused on the development of a progn... Some studies have suggested that early surgical treatment can effectively improve the prognosis of cervical spinal cord injury without radiological abnormality,but no research has focused on the development of a prognostic model of cervical spinal cord injury without radiological abnormality.This retrospective analysis included 43 patients with cervical spinal cord injury without radiological abnormality.Seven potential factors were assessed:age,sex,external force strength causing damage,duration of disease,degree of cervical spinal stenosis,Japanese Orthopaedic Association score,and physiological cervical curvature.A model was established using multiple binary logistic regression analysis.The model was evaluated by concordant profiling and the area under the receiver operating characteristic curve.Bootstrapping was used for internal validation.The prognostic model was as follows:logit(P)=-25.4545+21.2576VALUE+1.2160SCORE-3.4224TIME,where VALUE refers to the Pavlov ratio indicating the extent of cervical spinal stenosis,SCORE refers to the Japanese Orthopaedic Association score(0–17)after the operation,and TIME refers to the disease duration(from injury to operation).The area under the receiver operating characteristic curve for all patients was 0.8941(95%confidence interval,0.7930–0.9952).Three factors assessed in the predictive model were associated with patient outcomes:a great extent of cervical stenosis,a poor preoperative neurological status,and a long disease duration.These three factors could worsen patient outcomes.Moreover,the disease prognosis was considered good when logit(P)≥-2.5105.Overall,the model displayed a certain clinical value.This study was approved by the Biomedical Ethics Committee of the Second Affiliated Hospital of Xi’an Jiaotong University,China(approval number:2018063)on May 8,2018. 展开更多
关键词 nerve REGENERATION SURGICAL prognostic model CERVICAL SPINAL cord injury retrospective study MULTIPLE binary logistic regression analysis BOOTSTRAPPING internal validation MULTIPLE imputations CERVICAL SPINAL stenosis duration of disease Pavlov ratio neural REGENERATION
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Anterior cervical corpectomy decompression and fusion for cervical kyphosis in a girl with Ehlers-Danlos syndrome: A case report 预览
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作者 Huang Fang Peng-Fei Liu +4 位作者 Chang Ge Wen-Zhi Zhang Xi-Fu Shang Cai-Liang Shen Rui He 《世界临床病例杂志》 2019年第4期532-537,共6页
BACKGROUND Spinal deformities in Ehlers-Danlos syndrome (EDS;type VI) are generally progressive and severe. Surgical treatment has been described for kyphoscoliosis in the thoracolumbar spine. However, there are few s... BACKGROUND Spinal deformities in Ehlers-Danlos syndrome (EDS;type VI) are generally progressive and severe. Surgical treatment has been described for kyphoscoliosis in the thoracolumbar spine. However, there are few studies describing the consequences of an anterior approach in cervical kyphosis. An anterior approach may not be able to fully decompress the spinal canal and restore the normal curvature of the cervical spine. Therefore, the anterior approach for cervical kyphosis in young children is hard. We describe the first case in an EDS girl with cervical kyphosis who received satisfactory anterior cervical corpectomy decompression and fusion. CASE SUMMARY The chief complaints of a 16-year-old girl with EDS were double upper limb weakness for 7 years and double lower limb walking instability for 2 years. Moreover, the imaging results revealed that the degree of kyphosis from cervical vertebra 2 to 4 accompanying with spinal cord compression was 30°. An anterior cervical corpectomy involving cervical vertebra 3 and a titanium mesh implant were performed with internal fixation. The results at 3 mo after surgery demonstrated that the anterior fusion was solid, and the kyphosis of the cervical spine was corrected. Additionally, the power of all four extremities was significantly improved. CONCLUSION The incidence rate of cervical kyphosis in EDS is rare. The surgical treatment for these patients, especially an anterior approach, is challenging. Therefore, to develop safer and more effective strategies to treat cervical kyphosis in EDS, there is still much work to do. 展开更多
关键词 CERVICAL KYPHOSIS EHLERS-DANLOS syndrome Anterior CERVICAL CORPECTOMY DECOMPRESSION and FUSION Case report
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宫颈人乳头瘤病毒感染调查与危险因素分析 被引量:1
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作者 郎妙双 马陈美 孙丽萍 《中国预防医学杂志》 CAS CSCD 2019年第5期442-445,共4页
目的探究本地区宫颈人乳头瘤病毒(HPV)感染情况及危险因素,为HPV感染的预防提供依据。方法选择2017年1月至2018年12月永康市中医院妇产科就诊的自愿接受宫颈HPV感染筛查的女性3 502例作为研究对象,宫颈细胞样本采用聚合酶链式反应-反向... 目的探究本地区宫颈人乳头瘤病毒(HPV)感染情况及危险因素,为HPV感染的预防提供依据。方法选择2017年1月至2018年12月永康市中医院妇产科就诊的自愿接受宫颈HPV感染筛查的女性3 502例作为研究对象,宫颈细胞样本采用聚合酶链式反应-反向斑点杂交法(PCR—RDB)检测HPV阳性表达率及基因分型,结合保密式问卷调查结果分析危险因素。结果 3 502例患者中,共检出HPV阳性908例,HPV感染率为25.93%(908/3502),主要以单一型感染为主。908例HPV阳性者(HPV病毒感染1 072次),共检出14种HVP亚型,包括11种高危型、3种低危型。高危型感染率最高的亚型为HPV52,低危型感染率最高的亚型为HPV6(P<0.05)。单因素分析结果显示,年龄、文化程度、家庭平均月收入、初次性行为年龄、怀孕次数、产次、性伴侣数与HPV感染有关(P<0.05)。多因素分析结果提示家庭月收入低、初次性行为年龄<20岁、怀孕次数≥2次、性伴侣人数≥2人是HPV感染的高危影响因素。结论本地区HPV感染率较高,主要感染的HPV基因高危亚型为HPV52、低危亚型为HPV6,危险因素较多,应重视易感女性群体的HPV检测,及早发现宫颈上皮瘤变,降低宫颈癌发病率。 展开更多
关键词 宫颈 人乳头瘤病毒 聚合酶链式反应-反向斑点杂交法 危险因素 宫颈癌 筛查
Schwannomas—Atypical Presentation and Challenges 预览
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作者 R. Vijai J. Ruban Kumar +4 位作者 R. Arihanth Manoj Prabu Narayanasami Bharath Khalilur Rahman Arcot Rekha 《临床医学病理报告(英文)》 2019年第4期93-98,共6页
Introduction: Neurogenic tumors include schwannomas and neurofibro-mas. They occur often in the head and neck. However, their occurrence on the vagus is uncommon. A high index of suspicion is needed to order imaging i... Introduction: Neurogenic tumors include schwannomas and neurofibro-mas. They occur often in the head and neck. However, their occurrence on the vagus is uncommon. A high index of suspicion is needed to order imaging in pelvic lesions that present atypically. Discussion: Schwannomas are hypointense on T1 and heterogeneously hyperintense on T2 on MRI. The histopathological appearance with Antoni type A and type B is typical of Schwannoma. Conclusion: Schwannomas are slow growing benign tumors that are separable from the parent nerve. Recurrence is uncommon after resection. 展开更多
关键词 CERVICAL Presaccral IHC
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椎管扩大成形术-发展及展望 预览
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作者 王文轩 赵斌 +3 位作者 陆向东 王永峰 赵轶波 赵晓峰 《海南医学院学报》 CAS 2019年第5期396-400,共5页
颈椎椎管扩大成形术作为椎板切除术的替代术式,通过将椎板抬高从而扩大脊髓可用空间,达到间接减压效果以治疗颈椎病。在Hirabayashi的单开门及Kurokawa的双开门两种原型技术基础上,各种椎管扩大成形术得以不断发展。相比于椎板切除术,... 颈椎椎管扩大成形术作为椎板切除术的替代术式,通过将椎板抬高从而扩大脊髓可用空间,达到间接减压效果以治疗颈椎病。在Hirabayashi的单开门及Kurokawa的双开门两种原型技术基础上,各种椎管扩大成形术得以不断发展。相比于椎板切除术,多项研究表明椎板成形术后颈椎表现出更好的生物力学稳定性。椎管扩大成形术的最新研究进展围绕保留肌肉、韧带附着点,从而使由颈伸肌群控制的颈椎保持动态及静态稳定。接受了新型椎板成形术治疗的患者,结合术后积极的颈部肌肉功能锻炼,术后颈椎失稳、后凸畸形、轴性症状以及颈椎活动度的下降都进一步减少。多项临床试验表明这种新型术式可以保证患者术后疗效的同时提供颈椎的即刻稳定性。现就对颈椎椎管扩大成形术的发展、并发症以及未来趋势综述如下。 展开更多
关键词 颈椎 脊髓病 椎管扩大成形术 颈椎稳定性
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颈部淋巴结结核超声造影指导下粗细针穿刺活检的对比分析
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作者 张文智 杨高怡 +2 位作者 钟方明 于天琢 王玲玲 《中国超声医学杂志》 CSCD 北大核心 2019年第10期884-886,共3页
目的对超声造影后行穿刺活检的87例颈部淋巴结肿大患者的病理结果进行回顾性分析,比较颈部淋巴结结核两种穿刺活检术的优势。方法所有患者随机分为A、B两组,穿刺术前经超声造影选择穿刺点及目标淋巴结,A组行细针穿刺活检,取出物涂片后用... 目的对超声造影后行穿刺活检的87例颈部淋巴结肿大患者的病理结果进行回顾性分析,比较颈部淋巴结结核两种穿刺活检术的优势。方法所有患者随机分为A、B两组,穿刺术前经超声造影选择穿刺点及目标淋巴结,A组行细针穿刺活检,取出物涂片后用95%酒精固定;B组行粗针穿刺活检,组织用10%甲醛固定。两组穿刺物均送病理检查,比较病理诊断阳性率。结果A组颈部淋巴结结核病理诊断阳性率95%(38/40),B组颈部淋巴结结核病理诊断阳性率100%(47/47),两组相近(χ^2=0.69,P>0.05);术后窦道及窦道趋势发生率A组2.50%,B组12.76%,B组高于A组。结论超声造影后颈部淋巴结结核粗针穿刺活检的病理诊断阳性率与细针穿刺活检相近,而并发症发生率粗针活检高。 展开更多
关键词 颈部 淋巴结结核 超声造影 穿刺活检
Nomograms based on HPV load for predicting survival in cervical squamous cell carcinoma: An observational study with a longterm follow-up 预览
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作者 Jing Zuo Ying Huang +4 位作者 Jusheng An Xi Yang Ning Li Manni Huang Lingying Wu 《中国癌症研究:英文版》 SCIE CAS CSCD 2019年第2期389-399,共11页
Objective: To investigate the prognostic value of pretreatment human papillomavirus(HPV) viral load for cervical cancer, and to develop nomograms based on HPV load and other clinicopathological factors for long-term s... Objective: To investigate the prognostic value of pretreatment human papillomavirus(HPV) viral load for cervical cancer, and to develop nomograms based on HPV load and other clinicopathological factors for long-term survival.Methods: We conducted a prospective study on cervical squamous cell carcinoma(SCC) patients diagnosed between January 2003 and December 2008. Cervical samples were tested for HPV viral load by the Hybrid Capture II(HCII) assay before treatment and 6 months after treatment. Clinical characteristics and follow-up information were also collected. A multivariable Cox proportional hazards model was used to adjust covariates in both the radical hysterectomy(RH) treatment group and concurrent chemoradiotherapy(CCRT) treatment group to identify relevant covariates, and then nomograms were constructed and used for internal validation.Results: A total of 520 SCC patients enrolled in this study with a median follow-up of 127 months, 360 patients received RH, whereas 160 patients received CCRT. The median HPV viral load in RH and CCRT groups was356.10 and 294.29, respectively. Tumor size was positively correlated with high pretreatment HPV load in both groups. In CCRT group, the advanced International Federation of Gynecology and Obstetrics(FIGO) stage and enlarged retroperitoneal lymph node status determined by computed tomography(LNSCT) were correlated with low HPV load group. Initial HPV viral load, FIGO stage and lymph node metastasis were prognostic factors for RH group, whereas HPV viral load, squamous cell carcinoma antigen(SCC-Ag) level and LNSCT were identified as prognostic factors for CCRT group. Nomograms incorporating these predictors for 10-year progression-free survival(PFS) were constructed [concordance index(C-index): 0.756, 0.749].Conclusions: A low pretreatment HPV viral load is an independent prognostic factor for poor prognosis of cervical SCC and is related to other clinicopathological factors. The survival nomogram based on HPV viral load could predict the long-term prognosis. 展开更多
关键词 Cervical SQUAMOUS cell carcinoma human PAPILLOMAVIRUS viral LOAD SURVIVAL NOMOGRAM
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消敏饱和灸量艾灸联合针刺对于颈型颈椎病患者的疗效评价 预览
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作者 金敏 韩冰 王孝维 《上海针灸杂志》 2019年第8期922-926,共5页
目的观察消敏饱和灸量艾灸联合针刺治疗颈型颈椎病患者的临床疗效.方法选取颈型颈椎病患者100例,按照随机分配原则将其分为观察组50例、对照组50例.对照组接受常规灸量艾灸联合针刺治疗,观察组接受消敏饱和灸量艾灸联合针刺治疗.以临床... 目的观察消敏饱和灸量艾灸联合针刺治疗颈型颈椎病患者的临床疗效.方法选取颈型颈椎病患者100例,按照随机分配原则将其分为观察组50例、对照组50例.对照组接受常规灸量艾灸联合针刺治疗,观察组接受消敏饱和灸量艾灸联合针刺治疗.以临床症状积分、McGill疼痛问卷以及Northwick Park疼痛量表对患者治疗前后进行评估,对比两组差异.结果第5次治疗后、疗程结束时、随访第1及第3个月两组患者临床症状积分均显著改善(P<0.05),McGill疼痛问卷评分均显著减少(P<0.05),Northwick Park疼痛量表评分均显著减少(P<0.05).相比于对照组,观察组患者第5次治疗后、疗程结束时、随访第1及第3个月临床症状积分改善更为显著(P<0.05),McGill疼痛问卷以及Northwick Park疼痛量表评分更低(P<0.05).结论艾灸联合针刺对于颈型颈椎病的治疗效果值得肯定,而消敏饱和灸量艾灸联合针刺对于治疗效果的提升更为明显,其主要表现为临床症状的缓解以及患者近、远期局部疼痛感觉的下降. 展开更多
关键词 颈椎病 颈型 艾条灸 针刺疗法 疼痛评估 McGill疼痛问卷 Northwick Park疼痛量表 皮内针疗法
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Diagnostic value of HPV and P16 protein in patients with HSIL and prognosis
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作者 Chun-Yan Hu Gen-Hai Zhu +2 位作者 Ai-Wen Xing Kai-Ying Cui Ji-Min Chen 《海南医科大学学报(英文版)》 2019年第10期53-56,共4页
Objective: To investigate the diagnostic value and prognostic value of HPV and P16 protein in patients with HSIL and to provide a reference for the clinical diagnosis and assessment of the prognosis of patients with H... Objective: To investigate the diagnostic value and prognostic value of HPV and P16 protein in patients with HSIL and to provide a reference for the clinical diagnosis and assessment of the prognosis of patients with HSIL. Methods: The surgical treatment of HSIL patients from January 2013 to January 2015 in our hospital were selected. All patients were routinely tested for HPV and P16 protein, All patients were followed up for 1 year. Patients were divided into progressive group and quiescent group according to whether the disease progressed one year after surgery. Preoperative HPV and P16 protein levels were compared between the two groups. Using receiver operating curve (ROC curve) Analysis of HPV diagnostic value of HSIL. The levels of HPV and P16 protein in the two groups were analyzed and compared. Results: The quantitative level of high-risk HPV-DNA after LEEP was significantly lower than that before operation. The level of P16 protein in preoperative patients was higher than that before operation, and the difference was statistically significant. There were 21 patients in the postoperative progression group, and the average HPV-DNA content in the patients in the progression group was higher than that in the control group within one year after operation. The difference was statistically significant. The P16 protein level in patients in advanced group was significantly higher than that in resting group. Preoperative HPV-DNA levels and P16 protein levels in patients with progressive disease were significantly higher than those in still group. ROC curve analysis showed that the cut-off value of 2.441, HPV-DNA prediction of HSIL patients one year after the recurrence of the sensitivity was 95.12%, the specificity was 76.16%, under the curve area of 0.878;7.4 cut-off value, P16 The predictive value of HSIL patients recurrence after 1 year was 71.95%, specificity was 66.67%, and the area under the curve was 0.753. The recurrence group HPV-DNA content and P16 protein level showed a significant positive correlation, 展开更多
关键词 Highly SQUAMOUS intraepithelial LESION Intraepithelial NEOPLASIA Human PAPILLOMAVIRUS CERVICAL cancer P16 protein
Comparison of efficacy and safety between late-course and simultaneous integrated dose-increasing intensity-modulated radiation therapy for cervical cancer complicated with pelvic lymph node metastasis 预览
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作者 Yi Cheng Nan Huang +3 位作者 Jing Zhao Jianhua Wang Chen Gong Kai Qin 《肿瘤学与转化医学:英文版》 2019年第1期25-29,共5页
Objective This study aimed to compare and analyze the clinical efficacy and safety of late-course and simultaneous integrated dose-increasing intensity-modulated radiation therapy(IMRT) for cervical cancer complicated... Objective This study aimed to compare and analyze the clinical efficacy and safety of late-course and simultaneous integrated dose-increasing intensity-modulated radiation therapy(IMRT) for cervical cancer complicated with pelvic lymph node metastasis. Methods Sixty patients with cervical cancer complicated with pelvic lymph node metastasis who were admitted to our hospital from January 2013 to January 2015 were enrolled. The patients were randomly divided into the late-course dose-increasing IMRT group and the simultaneous integrated dose-increasing IMRT group, with 30 cases included in each group, respectively. All patients were concurrently treated with cisplatin. After treatment, the clinical outcomes of the two groups were compared. Results The remission rate of symptoms in the simultaneous integrated dose-increasing IMRT group was significantly higher than that in the late-course dose-increasing IMRT group(P < 0.05). The follow-up results showed that the overall survival time, progression-free survival time, and distant metastasis time of patients in the simultaneous integrated dose-increasing IMRT group were significantly longer than those in the late-course dose-increasing IMRT group(P < 0.05). The recurrent rate of lymph nodes in the radiation field in the simultaneous integrated dose-increasing IMRT group was significantly lower(P < 0.05) than in the late-course dose-increasing IMRT group. There was no significant difference in the incidence of cervical and vaginal recurrence and distant metastasis between the two groups(P > 0.05). The radiation doses of Dmax in the small intestine, D1 cc(the minimum dose to the 1 cc receiving the highest dose) in the bladder, and Dmax in the rectum in the simultaneous integrated dose-increasing IMRT group were significantly lower(P < 0.05) than in the late-course dose-increasing IMRT group. There was no significant difference in intestinal D2 cc(the minimum dose to the 2 cc receiving the highest dose) between the two groups(P > 0.05). The incidence of bone marrow suppr 展开更多
关键词 simultaneous integrated dose-increasing INTENSITY-MODULATED radiation therapy late-course dose-increasing INTENSITY-MODULATED radiation therapy cervical cancer COMPLICATED with pelvic lymph node metastasis clinical efficacy safety
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Non-Invasive management of invasive cervical resorption associated with periodontal pocket: A case report 预览
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作者 Abdullah Alqedairi 《世界临床病例杂志》 2019年第7期863-871,共9页
BACKGROUND Invasive cervical resorption (ICR), a commonly misdiagnosed condition, is an aggressive form of external tooth resorption that contributes to periodontal tissue inflammation and deepening of the periodontal... BACKGROUND Invasive cervical resorption (ICR), a commonly misdiagnosed condition, is an aggressive form of external tooth resorption that contributes to periodontal tissue inflammation and deepening of the periodontal pockets. Herein we report the case of a patient, exhibiting ICR and elaborate the effects of a non-surgical approach in the amelioration of this condition. CASE SUMMARY A 21-year-old female reporting intermittent pain at the upper left side, multiple restorations, no trauma history, and having received orthodontic treatment was studied. Localized erythematous swelling was noted at the buccal interdental papilla between the left maxillary first molar and second premolar. The diseased pulp and tissue in resorption were removed and the root canal system including the defect were sealed using gutta percha/AH Plus and mineral trioxide aggregate (MTA). At the one-year recall, the tooth showed no symptoms and responded normally to percussion and palpation. The surrounding periodontium exhibited a normal color and the probing depth was normal. Radiographic examination showed a restoration of crestal alveolar bone and good adaption to MTA. CONCLUSION Non-surgical root canal treatment in conjunction with resorption defect orthograde repair with MTA was found to be an effective treatment option in the elimination of ICR. Early diagnoses are recommended in order to employ nonsurgical approaches for management of ICR instead of surgical interventions. 展开更多
关键词 INVASIVE CERVICAL RESORPTION Mineral TRIOXIDE aggregate NON-SURGICAL root canal PERIODONTAL Case report
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Comparison of transvaginal cervical length and modified Bishop's score as predictors for labor induction in nulliparous women
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作者 El Mekkawi SF Hanafi S +2 位作者 Khalaf-Allah AE Ibrahim A.Abdelazim Mohammed EK 《亚太生殖杂志(英文版)》 2019年第1期34-38,共5页
Objective: To compare the transvaginal cervical length (TVCL) to the modified Bishop's score for prediction of successful labor induction in nulliparous women. Methods: A total of 210 nulliparous women who were di... Objective: To compare the transvaginal cervical length (TVCL) to the modified Bishop's score for prediction of successful labor induction in nulliparous women. Methods: A total of 210 nulliparous women who were diagnosed as premature rupture of membranes were recruited in this comparative prospective study, which was carried out in the Obstetrics and Gynecology Department of Ain Shams University, Egypt over two years for labor induction. The studied women were examined by trans-vaginal ultrasound for measurement of the cervical length (CL) and vaginally to calculate the modified Bishop's score, followed by induction of labor. Collected data were analyzed to compare the TVCL to the modified Bishop's score for prediction of successful labor induction in nulliparous women. The success of induction process was defined as vaginal birth after the induction of labor. Results: One hundred and forty-three women of studied women had CL <28 mm;122 of them delivered vaginally (P=0.030). One hundred and forty-six women of studied women had modified Bishop's score >4;128 of them delivered vaginally (P=0.006). The CL <28 mm was significantly more specific with more positive predictive value as predictor of successful labor induction compared to modified Bishop's score. Induction to delivery time was significantly shorter in women with CL <28 mm than women with CL ≥28 mm (P=0.02;95% confidence interval: 4.9-8.4). In addition, induction to delivery time was significantly shorter in women with Bishop's score >4 than women with Bishop's score of 曑4 (P=0.01;95% confidence interval: 1.6-4.5). Conclusions: Both TVCL and the modified Bishop's score are complementary tools in pre-induction cervical assessment before induction of labor, while the TVCL at <28 mm is significantly more specific with more positive predictive value as predictor of successful induction than the modified Bishop's score. 展开更多
关键词 CERVICAL length LABOR induction MODIFIED Bishop's SCORE
A preliminary cervical cancer screening cascade for eight provinces rural Chinese women: a descriptive analysis of cervical cancer screening cases in a 3-stage framework
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作者 Shu-Xia Wang Jiu-Ling Wu +4 位作者 Rui-Min Zheng Wei-Yi Xiong Jing-Yi Chen Lan Ma Xiao-Min Luo 《中华医学杂志:英文版》 SCIE CAS CSCD 2019年第15期1773-1779,共7页
Background:Cascade analysis is an effective method to analyze the processing data of an event,such as a provided service or a series of examinations.This study aimed to develop a primary cervical cancer screening casc... Background:Cascade analysis is an effective method to analyze the processing data of an event,such as a provided service or a series of examinations.This study aimed to develop a primary cervical cancer screening cascade in China to promote the quality of the screening process.Methods:We designed a cervical cancer screening cascade in China according to the program flow chart.It had three stages,each with two steps and one result.Data from 117,522 women aged 35 to 64 years in the Rural Cervical Cancer Surveillance Project from January 1,2014,to December 31,2014,were collected to analyze the main results of the cascade.The data and proportion are used to describe the follow-up of cervical cancer and pre-cancer detection rate.Results:In 2014,117,522 (80.94% of all cases reported by the Rural Cervical Cancer Surveillance Project) women aged 35 to 64 years had not received cervical cytology in the previous 3 years.The pre-cancer and cancer detection rates were 256.12/100,000 and 16.16/100,000,respectively.A total of 3031 cases failed to follow-up through the screening process,and 1189,1555,and 287 cases were lost at cervical cytology,colposcopy,and histopathological screening stages,respectively.The estimated cases of pre-cancer and cancer cases would have been 544 and 34,respectively,and the estimated detection rates of pre-cancer and cancer would have been 462.89/100,000 and 28.93/100,000,respectively.Conclusion:In order to increase the detection rate of cervical cancer,cervical cancer screening staff should focus on increasing the rate of follow-up of those who are positive for cervical cancer screening (ie,those with positive cytology results),especially for the 40 to 44 years age range. 展开更多
关键词 UTERINE CERVICAL neoplasms Mass screening China
Evaluation of the quality of randomized controlled trials on exercise for cervical radiculopathy
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作者 Long Liang Jie Yu +8 位作者 Min-Shan Feng Shuai-Qi Zhou He Yin Gong-Bo Yang Xun-LuYin Kai-Ming Li Rong Xie Xu Wei Li-Guo Zhu 《海南医科大学学报(英文版)》 2019年第13期65-71,共7页
Objective:To review and evaluate the quality of the randomized controlled trials of exercise for the treatment of cervical radiculopathy with the present internationally recognized CONSORT statement, which provides re... Objective:To review and evaluate the quality of the randomized controlled trials of exercise for the treatment of cervical radiculopathy with the present internationally recognized CONSORT statement, which provides reference and basis for the improvement of clinical research on exercise for intervening cervical radiculopathy in the future.Methods: A computer-based search of large domestic databases, including CNKI, Wanfang database and VIP database screened out literature that meet the requirements and used CONSORT statement for quality assessment.Results: According to the prescribed inclusion and exclusion criteria, 30 articles were retrieved in accordance with the standard. No literature was referred to the randomized controlled trial, 2 documents clearly defined the type of test design, 1 documents carried out the calculation of sample size, 13 documents clearly randomly assigned, 1 literature implemented the blind method, in the 7 literature, baseline information was shown in tabular form, and no reference was made to trial registration, trial protocol and funding.Conclusion:There are some aspects of randomized controlled trials on exercise for the treatment of cervical radiculopathy. However, there are some aspects that need to be improved. In the future randomized controlled trial report, the CONSORT statement should be highly valued and carefully considered to improve the accuracy and credibility of the research. 展开更多
关键词 Cervical RADICULOPATHY EXERCISE RANDOMIZED controlled trials QUALITY EVALUATION CONSORT statement
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