期刊文献+
共找到31,257篇文章
< 1 2 250 >
每页显示 20 50 100
文章速递Helicobacter Pylori Infections in Peptic Ulcer Perforations: A Retrospective Analysis in Two Referral Hospitals in Douala, Cameroon 认领
1
作者 Francois Adrien Morel Bokalli Chi Fru McWright +4 位作者 Jerry Brown Njoh Aseneh Takere Maseoli Mbachan Ngomba Divine Mokake Jules Clément Assob Nguedia Marcelin Ngowe Ngowe 《外科学(英文)》 2020年第10期298-311,共14页
<strong>Background:</strong> Perforations are major complications of peptic ulcer disease and surgical emergencies with important mortality and morbidity. <em>Helicobacter pylori (H. pylori)</em&g... <strong>Background:</strong> Perforations are major complications of peptic ulcer disease and surgical emergencies with important mortality and morbidity. <em>Helicobacter pylori (H. pylori)</em> has been identified as one of the commonest factors associated with peptic ulcer disease. However, little is known about its implication in cases of perforations in Cameroon. We aimed to determine the frequency of <em>Helicobacter pylori</em> infections in cases of perforated peptic ulcers, describe clinical features and outcomes of these cases in Cameroon. <strong>Method:</strong> A hospital-based retrospective cross-sectional study was conducted through the review of patients’ records admitted for peptic ulcer perforations in Laquintinie and Douala General Hospitals over a period of 5 years (January 2014 - December 2018). We defined <em>H. pylori</em> infection as;positive result on tissue biopsy at time of surgery. We used SPSS version 23.0 to analyse data and set an alpha value at P = 0.05. <strong>Results:</strong> We reviewed 115 cases of peptic ulcer perforation, with a mean age of 40 years and sex ratio (M:F) of 5:1. All patients underwent emergency laparotomy, 48 (41%) cases had a biopsy report and the prevalence of <em>H. pylori</em> infection in these cases was 47.9 %. Smoking, alcohol consumption and Non-Steroidal Anti-inflammatory Drugs (NSAIDs) use, were not associated with peptic ulcer perforation. The morbidity was at 43.7% and mortality at 14%. Mortality was increasing with a higher Mannheim Peritonitis Index score (OR: 23.51, 95% CI: 4.197 - 143.003, P-value: 0.000). <strong>Conclusion:</strong> We observed a high prevalence of <em>H. pylori</em> infection in patients with peptic ulcer perforations. We recommend systematic <em>H. pylori</em> screening in cases of perforations and that larger studies should be carried out to evaluate the association of <em>H. pylori</em> infection with peptic ulcer perforation in Sub-Saharan Africa. 展开更多
关键词 Perforated Peptic Ulcers Helicobacter pylori Infections Clinical Features Outcome
在线阅读 下载PDF
Materno-Fetal Outcomes of COVID-19 Infected Pregnant Women Managed at the Douala Gyneco-Obstetric and Pediatric Hospital—Cameroon 认领
2
作者 Alphonse Nyong Ngalame Humphry Tatah Neng +23 位作者 Rakya Inna Dominique Tamchom Djomo Diane Estelle Modjo Kamdem Bilkissou Moustapha Julie Ngo Batta Diomede Njinkui Noukeu Dominique Enyama Rodrigue Tiokeng Yannick Onana Yves Moumbe Martial Zanga Jules Fils Ndongo Armand Kamga Robert Tchounzou Ultrich Keumayou Lemone Chingnabo Toudjirob Djiallati Emmanuel Passoret Estella Toyoum Ramadji Jean Blaise Ebimbe Servais Albert F. Bagnaka Eloumou Darolles Wekam Mwadjie Guy Pascal Ngaba Emile Telesphore Mboudou 《妇产科期刊(英文)》 2020年第9期1279-1294,共16页
<strong>Introduction:</strong><span style="font-family:""><span style="font-family:Verdana;"> The first case of the novel coronavirus (COVID-19) pandemic in Cameroon wa... <strong>Introduction:</strong><span style="font-family:""><span style="font-family:Verdana;"> The first case of the novel coronavirus (COVID-19) pandemic in Cameroon was confirmed on March 6, 2020. Though widely considered that pregnant women are more susceptible to respiratory tract infections, the available body of literature on the effect of COVID-19 on pregnancy outcomes is shy from being conclusive. In Cameroon, the Douala Gyneco-Obstetric and Pediatric Hospital (DGOPH) was one of the main frontline tertiary health facilities for the management of severe forms of the disease. After four months of managing COVID-19 cases in the general population and especially in pregnant women at the DGOPH, we decided to take a stop, analyze our findings from the patients managed in order to drive future policies and clinical practices via informed decisions. </span><b><span style="font-family:Verdana;">Overall objective: </span></b><span style="font-family:Verdana;">To describe and understand the clinical burden of patients managed for COVID</span></span><span style="font-family:Verdana;">-</span><span style="font-family:""><span style="font-family:Verdana;">19 in pregnancy or post-partum at the DGOPH.</span><b><span style="font-family:Verdana;"> Methodology:</span></b><span style="font-family:Verdana;"> Cross</span></span><span style="font-family:Verdana;">-</span><span style="font-family:""><span style="font-family:Verdana;">sectional and descriptive study covering four months—March 24</span><sup><span style="font-family:Verdana;">th</span></sup><span style="font-family:Verdana;"> to July 24</span><sup><span style="font-family:Verdana;">th</span></sup><span style="font-family:Verdana;"> 2020 at DGOPH. Using a pretested questionnaire, we systematically enrolled all patients who fulfilled the inclusion criteria, with analysis done using proportions from an excel spreadsheet.</span><b><span style="font-family:Verdana;"> Results: </span></b><span style="font-family:Verdana;">A total of 18 on the 301 pregnant women consulte 展开更多
关键词 COVID-19 DGOPH PREGNANCY OUTCOME MORTALITY
在线阅读 免费下载
Trans-Thoracic Echocardiographic Aortic Blood Flow Peak Velocity Variation, Distance Minute, Aortic Velocity Time Integral and Postoperative Outcome in Pediatric Surgical Patients—An Observational Pilot Study Protocol 认领
3
作者 Claudine Kumba 《内科学期刊(英文)》 2020年第1期90-95,共6页
Background: A Randomized Controlled Trial (RCT) has been elaborated where goal directed fluid and hemodynamic therapy (GDFHT) will be realized with trans-thoracic echocardiographic aortic blood flow peak velocity vari... Background: A Randomized Controlled Trial (RCT) has been elaborated where goal directed fluid and hemodynamic therapy (GDFHT) will be realized with trans-thoracic echocardiographic aortic blood flow peak velocity variation (ΔVpeak) and distance minute (DM) to guide fluid therapy and hemodynamics in high risk pediatric surgical patients. This RCT will clarify the impact of GDFHT with ΔVpeak and DM on postoperative outcome in terms of morbidity, length of stay in the intensive care unit (LOSICU), length of mechanical ventilation (LMV) and length of hospital stay (LOS) in children. To determine values of ΔVpeak, DM and VTI predictive of these postoperative outcomes, an observational pilot study will be realized. This pilot study is described here. The primary objective of this study is to determine values of ΔVpeak, DM and ITV predictive of postoperative outcome in children in terms of morbidity. The secondary objectives are to determine values of ΔVpeak, DM and ITV predictive of LOSICU, LMV, LOS, intraoperative, postoperative fluid administration and vasoactive-inotropic therapy. Methods: 500 - 1000 children aged less than 18 years will be included prospectively. Statistic analysis will be realized with XLSTAT 2019.4.2 software or plus. Results and Conclusions: This trial protocol will determine values of ΔVpeak, DM and ITV with echocardiography predictive of postoperative outcome in children. 展开更多
关键词 Children AORTIC Blood Flow Peak VELOCITY Variation AORTIC VELOCITY Time INTEGRAL Distance MINUTE Postoperative Outcome Pilot Study Protocol Trans-Thoracic Echocardiography
在线阅读 免费下载
中医药治疗缓慢型心律失常随机对照临床试验采用的评价指标及问题分析 认领
4
作者 胡海殷 季昭臣 +5 位作者 李楠 王可仪 欧益 李凯 王辉 张俊华 《天津中医药》 CAS 2020年第4期414-421,共8页
[目的]分析2017—2018年发表的中药治疗缓慢型心律失常随机对照试验的评价指标,为今后中医药治疗缓慢型心律失常核心指标集的构建奠定基础。[方法]计算机检索中医药临床证据数据库(EVDS)、中国期刊全文数据库(CNKI)、万方、维普、SinoMe... [目的]分析2017—2018年发表的中药治疗缓慢型心律失常随机对照试验的评价指标,为今后中医药治疗缓慢型心律失常核心指标集的构建奠定基础。[方法]计算机检索中医药临床证据数据库(EVDS)、中国期刊全文数据库(CNKI)、万方、维普、SinoMed、PubMed、Cochrane Library,收集中医药干预的缓慢型心律失常临床随机对照试验(RCT)。检索时间为2017—2018年。由2位作者严格按照纳入与排除标准独立筛选文献、提取资料,如有分歧,经讨论解决。[结果]最终纳入71篇RCT,共计6129例患者,65个评价指标。单个研究采用指标数量为1~23个,平均为4.07个。使用频次排前14位的指标依次为:心率变化、临床疗效、不良反应、最慢心率、中医证候积分、中医证候疗效、24 h动态心电图平均心率、最快心率、心电图疗效、24 h动态心电图总心率、24 h动态心电图最慢心率、安全性指标、24 h动态心电图疗效、症状改善疗效。[结论]当前中药治疗缓慢型心律失常RCT在指标选择、指标参考标准、指标测量时间、测量方法等方面均存在一系列不规范问题,需要构建缓慢型心律失常临床试验核心指标集,为高质量中医药临床研究的设计和开展奠定基础。 展开更多
关键词 中医药 缓慢型心律失常 结局指标 核心指标集 随机对照临床试验
在线阅读 免费下载
Outcome of Maternal Anaemia on Cord Haemoglobin of the Newborn in Port Harcourt, Nigeria 认领
5
作者 Justina Omoikhefe Alegbeleye Dagogo Semenitari Abam Ngozi Clare Orazulike 《生物科学与医学(英文)》 2020年第5期142-152,共11页
Background: Anaemia is a common medical disorder in pregnancy especially in developing countries. Iron deficiency anaemia during pregnancy may be associated with adverse pregnancy outcomes Objectives: To?determine the... Background: Anaemia is a common medical disorder in pregnancy especially in developing countries. Iron deficiency anaemia during pregnancy may be associated with adverse pregnancy outcomes Objectives: To?determine the cord blood haemoglobin and the correlation between maternal haemoglobin concentration and perinatal outcome at the University of Port Harcourt Teaching Hospital. Materials and Methods: This was a prospective cross-sectional study of 155 pregnant women who presented at the labour ward of the department of Obstetrics and Gynaecology from October 1, 2018 to December 31, 2018. Blood sample was collected from the women in labour into ethylenediamine tetra-acetic acid (EDTA) bottles, red blood cell haemoglobin was determined. Umbilical cord blood sample was also collected at delivery and red cell haemoglobin was done. Socio-demographic characteristics, risk factors and perinatal outcome were obtained, entered into a spreadsheet and analyzed using SPSS 22.0. Bivariate logistic regression analysis was performed for multivariate analysis and statistical significance was considered at p Results: The mean age of the women was 31.08 ± 4.39 years, the mean maternal haemoglobin concentration was 11.54 ± 1.86 g/dl while the mean umbilical cord haemoglobin concentration was 12.92 ± 1.92 g/dl. Majority (86.45%) of the women were compliant with the prescribed haematinics. Moderate anaemia was observed in 17.42% of the women, followed by mild anaemia (15.48%) and severe anaemia (1.29%) respectively. Maternal complications were observed in 24.5% of women. There was a significant association between maternal haemoglobin concentration and cord blood haemoglobin concentration (p = 0.001). However, the study did not show an association between parity, mode of delivery, birth weight, Apgar scores, gestational age and maternal haemoglobin concentration (p > 0.05). Conclusion: The mean Haemoglobin in our newborns was less than previously reported values. Cord blood haemoglobin decreases significantly with decreasing matern 展开更多
关键词 MATERNAL HAEMOGLOBIN CORD Blood HAEMOGLOBIN Perinatal OUTCOME NIGERIA
在线阅读 免费下载
新型冠状病毒肺炎临床试验评价指标及相关问题 认领
6
作者 金鑫瑶 庞博 +8 位作者 王辉 王可仪 庞稳泰 郑文科 刘春香 杨丰文 张永刚 于春泉 张俊华 《天津中医药》 CAS 2020年第10期1109-1113,共5页
[目的]对已注册的新型冠状病毒肺炎(COVID-19)临床研究方案的评价指标进行分析,为提高相关临床研究疗效评价指标的合理性及核心指标集研制提供参考。[方法]以新型冠状病毒肺炎、Novel coronavirus pneumonia、2019-nCoV等为关键词,分别... [目的]对已注册的新型冠状病毒肺炎(COVID-19)临床研究方案的评价指标进行分析,为提高相关临床研究疗效评价指标的合理性及核心指标集研制提供参考。[方法]以新型冠状病毒肺炎、Novel coronavirus pneumonia、2019-nCoV等为关键词,分别检索中国临床试验注册中心(www.chictr.org.cn)与美国临床试验注册平台(clinicaltrials.gov),获取各种干预措施防治COVID-19的临床研究方案,提取研究基本信息与所有疗效评价指标数据,对评价指标情况进行描述性分析。[结果]共纳入研究方案78个,使用259个评价指标,共计596次,其中主要评价指标104个,使用184次,次要评价指标205个,使用412次。单个研究使用评价指标数量为1~15个,平均为8个。通过规范化处理,最终将259个指标统一为132个,涵盖临床症状、理化检查、病原学检测、重大事件、生活质量、疾病转归、中医指标、安全性指标8个指标域。[结论]目前COVID-19临床试验方案采用的评价指标存在表述不规范、测量时点不清、相似研究评价指标差异大、指标与研究目的不匹配等问题,需要建立COVID-19临床试验核心指标集(COSCOVID),为相关方案优化和新研究开展提供依据。 展开更多
关键词 新型冠状病毒肺炎 临床试验 评价指标 核心指标集
在线阅读 免费下载
Assessment of Contributions of Community Tuberculosis Intervention to Tuberculosis Case Detection and Treatment Outcome in Two States in Nigeria 认领
7
作者 Audu Onyemocho Hassan Abiodun +5 位作者 Queen Ogbuji Adewale Osho Shember-Agela Igbabul Gajere Julius Omole Victoria Nanben Anejo-Okopi Joseph 《结核病研究(英文)》 2020年第3期136-147,共12页
<b>Background: </b>Nigeria<i>,</i> one of the high burden Tuberculosis countries<i>,</i> has developed various intervention strategies to ensuring universal access to quality-assure... <b>Background: </b>Nigeria<i>,</i> one of the high burden Tuberculosis countries<i>,</i> has developed various intervention strategies to ensuring universal access to quality-assured tuberculosis diagnosis and treatment. However<i>,</i> low case detection and unsuccessful treatment outcome still remains a serious challenge in most states. Community Tuberculosis care was born against this background in 2010 as a complementing front to combat the challenges<i>,</i> bringing directly observed treatment short-course strategy beyond the clinic settings to the door steps of patients. This study evaluates the contributions of the intervention to Tuberculosis case detection and treatment outcomes in two states in Nigeria. <b>Materials and Method:</b> A retrospective study with multistage sampling technique was employed to review 23<i>,</i>241 presumptive Tuberculosis cases enrolled for management between 2014-2017. Chi-square (<i>χ</i><sup>2</sup>) test was used for test of association between the independent variables and the main outcomes of the study<i>,</i> with statistical significance set at p-value of 5%. <b>Results</b>: The annual percentage increase for both states was 24.7%<i>,</i> 189.8% and 114.5% in the study group as against 5.2%<i>,</i> 44.6% and 65.6% in control group. Overall<i>,</i> 23.8% were bacteriologically positive (either AFB or Gene-Xpert MTB/Rif) and 1.4% were clinically evaluated to be positive<i>,</i> while 74.8% were bacteriologically negative. Of the total 5861 cases treated<i>,</i> successful treatment rate of the patients in the study group was 88.6% as compared to 76.1% in the control group. The relationship between the referral system from communities where the intervention program was implemented and the case detection/treatment outcome was statistically significant (OR 95% CI = 3.15<i>,</i> 2.95 - 3.35). <b>Conclusion</b>: The community level Tuberculosis intervention led to significantly better case detection and treatment outcome when compared to the conventional approach (p ≤ 0.0 展开更多
关键词 Case Detection Community Care CONTRIBUTION TUBERCULOSIS Treatment Outcome
在线阅读 免费下载
Pregnancy in Coronavirus Disease (COVID-19) Pandemic: Clinical Opinion 认领
8
作者 Laila Yahya A. Alhubaishi Atif Bashir Eltayeb Fazari 《妇产科期刊(英文)》 2020年第5期708-713,共6页
Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus. This novel coronavirus is called SARS-COV-2 and the disease that it causes is called COVID-19 causes serious respirator... Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus. This novel coronavirus is called SARS-COV-2 and the disease that it causes is called COVID-19 causes serious respiratory morbidity and mortality. We aim to spot COVID-19 disease during pregnancy during this pandemic era. COVID-19 has various clinical presentations almost same in pregnant and non-pregnant victims. The hallmark for treatment is supportive management. Vertical transmission is probable but still not well confirmed and no evidence for virus in amniotic fluid, cord blood, neonatal throat swabs, placenta swabs, genital fluid and breastmilk samples from COVID-19 infected mothers. Research is running everywhere looking step ahead for actual treatment and vaccination. COVID-19 is newly emerged disease still not well explored in many aspects looking for soon definite treatment and vaccination for prevention to roll COVID-19. 展开更多
关键词 Coronavirus-COVID-19 PREGNANCY HYDROXYCHLOROQUINE MATERNAL MORBIDITY MATERNAL Mortality Neonatal Outcome TERATOGENICITY Low Resources Countries
在线阅读 免费下载
Outcome of the Post-Operative Patients’ Admissions in the Field of Resuscitation in Mali 认领
9
作者 Samaké Broulaye Massaoulé Beye Seydina Alioune +3 位作者 Tchaou Blaise Adélin Kassogué André Tall Fadima Koureissi Keita Mohamed 《麻醉学期刊(英文)》 2020年第3期73-79,共7页
Introduction: In spite of the use of the less and less invasive and the more and more effective techniques and the use of fast rehabilitation conditions of the patients in surgery, the post-operative complications (PO... Introduction: In spite of the use of the less and less invasive and the more and more effective techniques and the use of fast rehabilitation conditions of the patients in surgery, the post-operative complications (POC) stay the main reasons of admission in resuscitation service. Objective: To determine the post-operative outcome of the patients admitted in resuscitation. Patient and method: It was about a retrospective and transverse survey from June 2017 to May 2018 in the service of polyvalent resuscitation of the academic hospital center of Gabriel Touré. Have been included the patients operated for surgical or obstetric gynecology—pathologies admitted in resuscitation for post-operative complications established or potential precocious or late. The used statistical test was the Chi2 with p Results: During the period, 514 patients have been admitted in resuscitation of which 140 cases of post-operatively represented 27.2% of the admissions. Under hospitalization 35.7% of patients have presented a complication. The middle age of patients was 37.72 ± 20.9 years. The sex ratio was 0.70. The middle length of interventions was 122 ± 83 min with extremes going from 20 to 434 min. The predominant admission motive was hemodynamic instability. The delay of appearance intervening of the complications was 3 days in 94%. The predominant complications were: respiratory (32%), infectious (28%) and Cardiovascular (20%). The middle length of hospitalization was of 3.36 ± 2.90 days. The death rate was 15%. The complications were related age, the class of Alteme?er, the ASA, and the perioperative undesirable events with p Conclusion: The post-operative admissions in resuscitation are frequent including several factors of morbi-mortality. A better management per and postoperative of the patients operated would reduce the death rate. The profile mark is the one of a patient admitted for hemodynamic instability. 展开更多
关键词 POST-OPERATIVE Admission OUTCOME RESUSCITATION Academic Hospital GABRIEL Touré
在线阅读 下载PDF
Factors Influencing the Use of Outcome Measures for Patients with Low Back Pain: A Survey of Nigerian Physiotherapists 认领
10
作者 Christian Arinze Okonkwo Peter Olanrewaju Ibikunle +3 位作者 Joseph Onuwa Umunnah Kenneth Umezulike Ani Gloria Ukamaka Mgbeojedo Peter Agba Awhen 《康复医学(英文)》 2020年第3期83-97,共15页
<strong><span style="font-family:Verdana;">Background:</span></strong><span style="font-family:Verdana;"> Low back pain is one of the important patients’ presenting&l... <strong><span style="font-family:Verdana;">Background:</span></strong><span style="font-family:Verdana;"> Low back pain is one of the important patients’ presenting</span><span style="font-family:Verdana;"> complain that requires expert management from the physiotherapists. Yet no work was available for reference on the use of outcome measures for its e</span><span style="font-family:;" "=""><span style="font-family:Verdana;">valuation by Nigeria physiotherapists. </span><b><span style="font-family:Verdana;">Objective:</span></b><span style="font-family:Verdana;"> This study, therefore, investigated the outcome measures used by Nigerian physiotherapists</span></span><span style="font-family:Verdana;"> to </span><span style="font-family:;" "=""><span style="font-family:Verdana;">e</span><span style="font-family:Verdana;">valuate patients with Low Back Pain and the fac</span><span style="font-family:Verdana;">tors that influenced their use. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> A survey questionnaire was posted to 306 randomly selected mem</span></span><span style="font-family:Verdana;">- </span><span style="font-family:;" "=""><span style="font-family:Verdana;">bers</span><span> </span><span style="font-family:Verdana;">of the Nigeria Society of Physiotherapy (NSP). Data were analyzed using f</span><span style="font-family:Verdana;">requency, percentages, mean, ANOVA, and Pearson’s Chi</span></span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">square. P</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">val</span><span style="font-family:;" "=""><span style="font-family:Verdana;">ue was placed at 0.05. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> 52.9% of the respondents (221) used a pain visual analog scale. Only 36.1% used LBP</span></span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">specific clin 展开更多
关键词 Outcome Measures Factors Influencing Their Use Low Back Pain Patients Nigeria Physiotherapists
在线阅读 免费下载
Management of Spontaneous Superficial Intracerebral Hematomas 认领
11
作者 Mohamed Mahmoud Ahmad Elsayed Abokresha 《现代神经外科学进展(英文)》 2020年第2期208-221,共14页
Background: Treatment of primary spontaneous superficial intracerebral hemorrhage (SSICH) is still controversial. The aim of this study is to investigate the effectiveness of craniotomy and early hematoma evacuation v... Background: Treatment of primary spontaneous superficial intracerebral hemorrhage (SSICH) is still controversial. The aim of this study is to investigate the effectiveness of craniotomy and early hematoma evacuation vs conservative (non operative) management in patients with SSICH. Methods: A prospective study of craniotomy and early hematoma removal vs. medical management was performed in 20 patients with cortical and subcortical (superficial) primary SSICH admitted to Assiut university hospital in one year period (March 2016-March 2017). Surgical or medical treatment was initiated immediately when patients admitted to hospital. We divided the patients into two groups according to type of treatment. Results: Age of the patients ranged from 2 months to 73 years (mean: 45.84 ± 23.28 years) among the 20 patients studied;13 (65%) were males and 7 (35%) were females. Glasgow coma scale (GCS) at admission was less than 8 in 25%, between 8 - 12 in 45% and 15 in 30% of the patients. Arterial hypertension was the most common associated medical disease (65%). Eleven of patients (55%) had ventricular extension. GCS at admission was the strongest factor affecting outcomes and determined the type of treatment. All patients with a GCS ≤ 8 (5 cases (25%) were died regardless the type of treatment and there was no significant statistical difference in this group in relation to type of treatment p-value (0.606). We had 6 cases (30%) with a GCS 15;all of them were treated conservatively and all of them survived with significant p-value (0.003). Nine patients (45%) had GCS 8 - 12;two of them were treated conservatively and died while the remaining seven patients were treated surgically;five of them survived with significant p-value (0.025). No significant statistical difference was found in the outcome between the surgical and the conservative group regarding having associated intracranial hemorrhage. Conclusions: After analyzing the results, we found that when the GCS is “8 - 12”, surgical intervention is recommended and c 展开更多
关键词 CRANIOTOMY INTRACEREBRAL HEMORRHAGE Medical MANAGEMENT Outcome Surgical Treatment
在线阅读 免费下载
Profile and Performance of Rigid Gas Permeable and Scleral Lenses on Keratoconic Patients in the Developing Contact Lens Practice Settings 认领
12
作者 Walter Kibet Yego Harun Chemjor 《眼科学期刊(英文)》 2020年第3期201-209,共9页
</span><b><span style="font-family:Verdana;">Purpose:</span></b><span style="font-family:Verdana;"> </b></span><b> </b><span style=&qu... </span><b><span style="font-family:Verdana;">Purpose:</span></b><span style="font-family:Verdana;"> </b></span><b> </b><span style="font-family:Verdana;">To present the profile of keratoconic contact lens wearers, alongside with per</span><span style="font-family:Verdana;">formance of corneal and scleral rigid gas permeable (RGP) at different stages of keratoconus based on limited diagnostic resources. </span><span style="font-family:Verdana;"><b></span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> </b></span><b><span> </span></b><span style="font-family:Verdana;">5-year Clinical records of keratoconic corneal and scleral RGP contact lens w</span><span style="font-family:Verdana;">earers were retrieved. Data on age, gender, visual acuity (VA), refraction (RE), stage of keratoconus and mode of correction among other variables w</span></span><span style="font-family:Verdana;">ere</span><span style="font-family:Verdana;"> obtained for analysis. Information pertaining to the outcome in pre and post-fit at different severity w</span><span style="font-family:Verdana;">as</span><span style="font-family:Verdana;"> determined. </span><span style="font-family:""><span style="font-family:Verdana;"><b></span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> </b></span><span style="font-family:Verdana;"> A total of 124 medical records were analyzed, with the age (20.86 ± 9.50 years), gender (58.9% male and 41.1% female), Laterality (57.3% bilateral, 26.6% right eye and left eye as 16.1%) and ethnicity (91.1% Africans and 8.9%</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">Asians). There were no significant differences in effects of lenses (RGP and Scleral lenses) across three stages in visual acuity and in three stages o</span><span style="font-family:""><span style="font-family:Verdana;">f severity H</span><sub><span style="font-family:Verdana;">RGP</span></sub><span style="font-family:Verdana;"> (2 展开更多
关键词 KERATOCONUS Visual Outcome Rigid Gas Permeable Scleral Lenses Developing Practices
在线阅读 免费下载
Frequency and Outcome of Meconium Aspiration Syndrome in Babies Born with Meconium-Stained Liquor at Secondary Care Hospital in Pakistan: A Case Series Study 认领
13
作者 Khadija Humayun 《儿科学期刊(英文)》 2020年第3期381-391,共11页
<strong>Background:</strong><span style="font-family:;" "=""><span style="font-family:Verdana;"> Meconium aspiration syndrome (MAS) in the newborn is characte... <strong>Background:</strong><span style="font-family:;" "=""><span style="font-family:Verdana;"> Meconium aspiration syndrome (MAS) in the newborn is characterized by hypoxia, hypercapnia, and acidosis. MAS is a leading cause of morbidity and mortality in neonates. The primary objective of this study was to estimate the frequency of meconium aspiration syndrome (MAP) in babies born with meconium-stained liquor. The secondary outcome was to estimate the meconium aspiration syndrome;in terms of hospital stay, complications, and mortality. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">The study was done at Aga Khan Maternal and Child Care Centre, Hyderabad, Pakistan. Study design was case series and the duration of the study was of 6 months. All patients who fulfilled the inclusion criteria were included in the study after taking informed written consent. A brief history was taken, clinical examination was done and laboratory investigations were sent to the institutional laboratory. Study outcomes were measured from this data </span><i><span style="font-family:Verdana;">i</span></i><span style="font-family:Verdana;">.</span><i><span style="font-family:Verdana;">e</span></i><span style="font-family:Verdana;">. MAS, its complications, mortality, and a number of days in the hospital. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">A total of 87 babies</span><b><i> </i></b><span style="font-family:Verdana;">born with meconium-stained liquor at secondary care hospital were included. A total of 45 patients (52%) were males and 42 patients (48%) were females with a mean gestational age of babies 38.896 </span></span><span style="font-family:;" "=""><span style="font-family:Verdana;">± </span><span style="font-family:Verdana;">1.210 weeks. The mean Apgar score at 5 minutes was 8.896 </span><span style="font-family:Verdana;">± </span><span><span style="font-family:Verdana;">0.404. MAS was present in 13 patients (14.9%) 展开更多
关键词 Meconium Aspiration Syndrome MORTALITY NEONATES OUTCOME
在线阅读 免费下载
Functional Outcomes of Decompressive Hemicraniectomy for Treatment of Malignant Infarctions of the Middle Cerebral Artery 认领
14
作者 Waleed Abbass 《现代神经外科学进展(英文)》 2020年第3期307-317,共11页
<strong>Introduction:</strong> Malignant middle cerebral artery (MCA) infarction is a devastating entity that is associated with up to 80% mortality. Decompressive Hemicraniectomy has been utilized to trea... <strong>Introduction:</strong> Malignant middle cerebral artery (MCA) infarction is a devastating entity that is associated with up to 80% mortality. Decompressive Hemicraniectomy has been utilized to treat brain swelling and mass effect secondary to these infarctions in an attempt to improve functional outcome. <strong>Aim: </strong>To evaluate the functional outcome of decompressive hemicraniectomy in management of malignant MCA infarctions. <strong>Methods: </strong>The study included 30 patients with malignant MCA infarctions operated upon by decompressive hemicraniectomy and duroplasty with pericranium or fascia lata graft in the period from June 2016 to January 2019. Pre-operative neurological condition, associated morbidity, location and extent of the infarction were assessed. Surgery was performed within 48 hours of the onset of stroke or 12 hours within deterioration of conscious level. Pre-operative CT scan as well as sequential post-operative CT was done. Functional outcome was assessed by the modified Rankin Scale (mRS) at the time of discharge and 3 months following surgery. <strong>Results: </strong>The study included 18 males and 12 females with a mean age of 54.7 years. The pre-operative GCS was <8 (5 - 7) in 11 patients and 8 or higher (8 - 13) in 19 patients. Good functional outcome (mRS 0 - 3) was achieved in 13 (43.3%) cases while poor outcome (mRS 4 - 5) occurred in 8 (26.7%) cases and mortality (mRS 6) occurred in 9 (30%) cases. <strong>Conclusion:</strong> Decompressive hemicraniectomy improves functional outcome in cases of malignant MCA infarction. Pre-operative GCS, age, volume of infarction, degree of midline shift, timing of surgery and associated morbidity are the most important factors affecting the outcome. 展开更多
关键词 Decompressive Hemicraniectomy Malignant MCA Infarction Functional Outcome Modified Rankin Scale
在线阅读 免费下载
Surgical Outcome of Traumatic Intracranial Hematoma 认领
15
作者 Hedaya Hendam Ahmed Taha 《现代神经外科学进展(英文)》 2020年第1期51-62,共12页
Objective: To evaluate the factors affecting the surgical outcome of traumatic intracranial hematoma. Patient and Methods: This study was retrospectively conducted on 60 patients with traumatic intracranial hematoma a... Objective: To evaluate the factors affecting the surgical outcome of traumatic intracranial hematoma. Patient and Methods: This study was retrospectively conducted on 60 patients with traumatic intracranial hematoma admitted to the Neurosurgery Department, Al-Azhar University Hospital and underwent surgical management. Results: The age range was 10 - 58 years, mean age was 31.50 years, male-to-female ratio was 3:1. The causative trauma was road traffic accident (45%), direct trauma to the head (30%) and fall from height (FFH) (25%) of all studied patients. Morbidity and/or mortality was reported in 38.3% and unfavorable outcome was significantly associated with longer delay time (time from injury to surgery), increased operative time, long duration of hospital stay and lower Glasgow coma scale at admission and discharge. Otherwise, the unfavorable outcome although increased with old age, there was no significant association. Conclusion: Head trauma is considered as a frequent cause of death and disability. Time consuming to reach the hospital, operative time, length of stay in hospital and Glasgow coma score of the patient on admission and discharge markedly determine the surgical outcome of traumatic intracranial hematoma. 展开更多
关键词 INTRACRANIAL HEMATOMA TRAUMA Surgical OUTCOME MORBIDITY MORTALITY
在线阅读 免费下载
Early Clinical and Functional Outcome of Primary Total Knee Replacement with Posterior Cruciate Substituting Prosthesis for Primary Knee Osteoarthritis Using 2011 Knee Society Score 认领
16
作者 Lukman Olalekan Ajiboye Taiwo Afolajuwanlo Adejumobi +2 位作者 Oluwaseyi Kayode Idowu Muhammad Oboirien Suleiman Olatunji Olarewaju 《健康(英文)》 2020年第5期514-522,共9页
Background: Primary knee Osteoarthritis (OA) is the commonest articular disease in middle age and elderly people. Primary total knee replacement (TKR) is a known world-wide standard and definitive treatment of primary... Background: Primary knee Osteoarthritis (OA) is the commonest articular disease in middle age and elderly people. Primary total knee replacement (TKR) is a known world-wide standard and definitive treatment of primary knee OA following failed adequate non-operative management. It is of clinical importance to assess the clinical and functional outcome of TKR to prognosticate the severity of primary knee OA. The new (2011) knee society scoring system (nKSS) is both surgeons and patients’ assessment tool for the treatment outcome of TKR. Study Design: Prospective interventional analytical study. Aim and Objective: The aim of the study was to determine early clinical and functional outcome of primary total knee replacement in patients with primary knee osteoarthritis using nKSS. The objectives were: 1) To determine the pre-operative nKSS and post operative nKSS;2) To determine relationships between pre-operative nKSS and post operative nKSS at 6 weeks, 3, 6, 9 and 12 months;3) To determine the complication rates in patients undergoing primary TKR in the study centre. Methods: A prospective interventional study of 59 patients aged 51 to 70 years who had 67 Total Knee Replacements (TKRs) participated in the study between November 2015 to June 2018 at National Orthopaedics Hospital, Lagos, Nigeria. Patients’ sociodemographic data, pre-operative and post-operative nKSS system were recorded at 6 weeks, 3, 6, 9 and 12 months during follow up. The data were analyzed using Statistical Package for Social Science (SPSS). Results: There were 41 females and 18 males (M:F = 1:2.3). There were total of 67 TKRs with 31 right TKRs, 20 left TKRs and 8 staged bilateral TKRs. The participants’ age ranged from 51 to 70 years with the mean age of 59.5 (±8.5) years. Four patients did not complete the study due to various reasons. The remaining 55 participants completed the study period with progressive improvement of their post-operative nKSS at 6 weeks, 3, 6, 9 and 12 months post-operatively when compared with pre-operative nKSS ( 展开更多
关键词 CLINICAL and Functional Outcome 2011 KNEE SOCIETY SCORE PRIMARY Total KNEE Replacement PRIMARY KNEE Osteoarthritis
在线阅读 免费下载
A Hospital-Based Cross-Sectional Study Assessing the Relation between Time of Birth and Perinatal Outcome 认领
17
作者 Mouhamadou Wade Papa Moctar Faye +8 位作者 Mame Diarra Ndiaye Mamour Gueye Simon Birame Ndour Abdoulaye Diakhate Ndama Niang Khalifa Fall Moussa Diallo Omar Gassama Magatte Mbaye 《儿科学期刊(英文)》 2020年第1期217-223,共7页
Objectives:?Investigating the relation between perinatal outcomes and?hospital working shifts.?Methods:?We conducted a cross-sectional study at Philippe Maguilen Senghor health center (PMSHC) in Dakar, Senegal from Ja... Objectives:?Investigating the relation between perinatal outcomes and?hospital working shifts.?Methods:?We conducted a cross-sectional study at Philippe Maguilen Senghor health center (PMSHC) in Dakar, Senegal from January, 1st?2011 to December, 31th 2018. The study population was comprised of all mothers who had delivered at PMSHC and their newborns after completing 22 weeks of gestation. Time of delivery was?divided into three periods of working hours: morning shift (deliveries occurred between 7 am and 4:59 pm);evening shift from 5 pm to 10:59 pm and night shift from 11?pm to 6:59 am.?Maternal outcomes were assessed by mode of delivery, epsisotomy and perineal injuries.?The Apgar scoring system was used to assess newborns at first minute after they were born. Other adverse perinatal outcomes included fresh stillbirth, neonatal referral and early neonatal death. Data were analyzed using Statistical Package for Social Science software (SPSS 24, Mac version).?Results:?A total of 48,270 mothers and their newborns met eligibility criteria. Caesarean section deliveries were less likely to occur during evening (OR 0.84, 95% CI;0.79?-?0.89, p = 0.001) and night shifts (OR 0.45, CI;0.47?-?0.53, p = 0.001).?Evening shift deliveries had 1.1 the odds of poor perinatal outcome (Apgar score ?- 1.18, p = 0.012). No significant difference was found in the odds of neonate referrals and deaths across the three shifts.?Night shift deliveries had 1.1 the odds of perineal injuries compared to morning shift deliveries (OR 1.11, 95% CI;1.04?- 1.18, p = 0.001, for episiotomy and OR, 1.14;95% CI, 1.04?- 1.26, p = 0.008, for perineal tears). Conclusion:?Off-hours deliveries, particularly during the night shift, were significantly associated with higher proportions of perineal injuries compared to morning shift.?However, no significant difference was found in the odds of neonate referrals and deaths across the three shifts.?Our findings suggest to set up a Neonatology unit at the CSPMS as well as a perinatal network across the country. 展开更多
关键词 PERINATAL Outcome TIME of BIRTH Low-Resource SETTING
在线阅读 免费下载
文章速递不同腹腔镜手术方式治疗早期子宫颈癌的肿瘤学结局比较 认领
18
作者 凌开建 王延洲 +19 位作者 张辉 张旭垠 杨隽钧 罗成燕 宋斌 张文希 邓黎 陈功立 李宇迪 胡群英 陈勇 王新 张军 丁景新 任彤 康山 华克勤 向阳 程文俊 梁志清 《中华妇产科杂志》 CAS CSCD 北大核心 2020年第9期617-623,共7页
目的探讨不同腹腔镜手术方式治疗早期子宫颈癌的肿瘤学结局的差异。方法收集2011年1月—2014年12月在国内6家医疗中心接受腹腔镜手术的子宫颈癌患者,临床分期为Ⅰb1、Ⅰb2、Ⅱa1、Ⅱa2期,病理类型为鳞癌、腺癌、腺鳞癌,有定期随访资料... 目的探讨不同腹腔镜手术方式治疗早期子宫颈癌的肿瘤学结局的差异。方法收集2011年1月—2014年12月在国内6家医疗中心接受腹腔镜手术的子宫颈癌患者,临床分期为Ⅰb1、Ⅰb2、Ⅱa1、Ⅱa2期,病理类型为鳞癌、腺癌、腺鳞癌,有定期随访资料。按照手术方式不同分为两组,包括改良经阴道辅助腹腔镜手术(改良腹腔镜组)、完全腹腔镜手术(完全腹腔镜组),比较两种手术方式的5年总生存率(OS)、5年无瘤生存率(DFS)等肿瘤学结局指标。结果共有674例子宫颈癌患者纳入本研究,其中改良腹腔镜组377例、完全腹腔镜组297例。(1)两组5年OS的比较:改良腹腔镜组、完全腹腔镜组患者的5年OS分别为96.1%、92.0%,改良腹腔镜组显著高于完全腹腔镜组(P=0.010)。进一步对临床分期(包括Ⅰb1、Ⅱa1期)、病理类型(鳞癌、腺癌)、淋巴结转移进行分层分析,结果显示,①临床分期:Ⅰb1患者的5年OS,改良腹腔镜组、完全腹腔镜组分别为98.6%、93.6%,两组比较,差异有统计学意义(P=0.012);Ⅱa1期患者的5年OS,改良腹腔镜组、完全腹腔镜组分别为93.6%、77.6%,两组比较,差异也有统计学意义(P=0.007)。②病理类型:改良腹腔镜组、完全腹腔镜组鳞癌患者的5年OS分别为96.1%、92.3%,两组比较,差异有统计学意义(P=0.046);腺癌患者的5年OS分别为91.0%、88.6%,两组比较,差异无统计学意义(P=0.230)。③淋巴结转移:改良腹腔镜组、完全腹腔镜组无淋巴转移患者的5年OS分别为98.6%、96.4%,有淋巴结转移患者的5年OS分别为89.3%、80.8%,两组分别比较,差异均无统计学意义(P=0.156,P=0.093)。(2)两组5年DFS的比较:改良腹腔镜组、完全腹腔镜组患者的5年DFS分别为94.1%、90.9%,两组比较,差异无统计学意义(P=0.220)。进一步对临床分期进行分层分析,结果显示,Ⅰb1期患者的5年DFS,改良腹腔镜组和完全腹腔镜组分别为97.0%、92.8%,两组比较,差异有统计学意义(P=0.039);Ⅱa1期患者的5年DFS,改良腹腔镜组、完全腹腔镜组分别为88.2%、75.8%,两组比较,差异无统计学意义(P=0.074)。结论不同腹腔镜手术方式可影响早期子宫颈癌患者的肿瘤学结局,改良经阴道辅助腹腔镜手术患者的5年OS高于完全腹腔镜手术患者,且其中Ⅰb1期患者的5年DFS也高于完全腹腔镜手术患者。提示,基于无瘤原则的改良经阴道腹腔镜手术仍可作为早期子宫颈癌手术治疗的选择。 展开更多
关键词 宫颈肿瘤 腹腔镜手术 治疗结果 存活率 回顾性研究
文章速递常州某三级医院糖尿病患者血流感染临床特点的回顾性分析 认领
19
作者 薛冰霜 薛一 +2 位作者 杨奇超 周姣姣 韦玉和 《中国医药科学》 2020年第19期243-246,共4页
目的分析糖尿病合并血流感染者的临床特征及病原菌特点,以指导临床治疗。方法回顾性分析2016年1月~2018年12月于常州市武进人民医院诊治的总计295例确诊为血流感染患者的临床资料。结果糖尿病合并血流感染患者中女性比例高于无糖尿病患... 目的分析糖尿病合并血流感染者的临床特征及病原菌特点,以指导临床治疗。方法回顾性分析2016年1月~2018年12月于常州市武进人民医院诊治的总计295例确诊为血流感染患者的临床资料。结果糖尿病合并血流感染患者中女性比例高于无糖尿病患者(P<0.05);糖尿病患者总住院时间长于无糖尿病患者(P<0.05);糖尿病血流感染患者转归好于无糖尿病患者(P<0.05);糖尿病血流感染患者大肠埃希氏菌比例高于无糖尿病患者(P<0.05);糖尿病患者肺部感染来源比例低于无糖尿病患者,尿路感染比例高于无糖尿病患者(P<0.05);糖尿病患者D-二聚体水平低于无糖尿病患者,血小板计数、糖化血红蛋白水平高于无糖尿病患者,差异均有统计学意义(P<0.05)。结论糖尿病患者更易发生血流感染;女性糖尿病患者更易发生血流感染,尤其是继发于尿路感染的大肠埃希菌血流感染。 展开更多
关键词 血流感染 糖尿病 转归 尿路感染
在线阅读 下载PDF
文章速递首次诊断为急性而短暂的精神病性障碍转归分析 认领
20
作者 吴惠玲 张爱国 王龙 《安徽卫生职业技术学院学报》 2020年第5期23-24,共2页
目的:探讨首次入院诊断为急性而短暂的精神性障碍(ATPD)的转归及其影响因素。方法:采用回顾性研究,收集首次入院诊断为ATPD患者139例,利用住院病历系统、门诊病历系统和电话随访,了解患者首次诊断后转归,分析影响转归的相关因素。结果:3... 目的:探讨首次入院诊断为急性而短暂的精神性障碍(ATPD)的转归及其影响因素。方法:采用回顾性研究,收集首次入院诊断为ATPD患者139例,利用住院病历系统、门诊病历系统和电话随访,了解患者首次诊断后转归,分析影响转归的相关因素。结果:34.5%维持ATPD原诊断,52.5%更改为精神分裂症,将转归为精神分裂症组与维持ATPD诊断患者分组比较,精神分裂症组患者较ATPD组发病年龄更早;病程更长,住院时间更长;ATPD患者男女发病比例为0.9:1。结论:首次诊断为ATPD的患者主要转归为精神分裂症,ATPD发病男女性别比例无显著差异。 展开更多
关键词 急性而短暂的精神病性障碍 转归 精神分裂
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部 意见反馈