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急性脑血管病心电图分析及临床意义研究 预览
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作者 金海霞 周建华 《临床医学进展》 2018年第8期765-768,共4页
目的:探究急性脑血管病的心电图特点及其在临床中的作用。方法:选择2015.08~2017.08期间于我院治疗的100例急性脑血管病患者作为研究对象,将其设为本研究的试验组(研究组);选择同期于我院进行健康体检的100例非脑血管病受检者,设其为对... 目的:探究急性脑血管病的心电图特点及其在临床中的作用。方法:选择2015.08~2017.08期间于我院治疗的100例急性脑血管病患者作为研究对象,将其设为本研究的试验组(研究组);选择同期于我院进行健康体检的100例非脑血管病受检者,设其为对照组。对所有的研究对象进行心电图检查,并对比二者在检查结果上的不同。结果:与对照组比较,研究组的动态心电图异常检出率明显增高;研究组与对照组相比,SDNN、rMSSD及SDANN等心率变异性时域指标均降低,且差异有统计学意义(P <0.05)。结论:急性脑血管病患者的心电图资料与患者病情密切相关,病情越重,心电图异常改变越多,其对临床上治疗预防脑血管病提供有效的参考依据。 展开更多
关键词 急性脑血管病 心电图 临床意义 脑心综合征
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影响糖尿病患者糖化血红蛋白含量的主要危险因素统计分析 预览
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作者 江峻瑜 张天芳 《统计学与应用》 2017年第4期455-459,共5页
本文的目的在于找出影响糖尿病患者糖化血红蛋白含量的主要危险因素。通过收集某医院在2015年1月至2016年12月间的糖尿病患者的临床及实验室数据资料,从中随机抽取10例具代表性、完善性的数据资料,然后使用超拉丁方抽样的方法对这些数... 本文的目的在于找出影响糖尿病患者糖化血红蛋白含量的主要危险因素。通过收集某医院在2015年1月至2016年12月间的糖尿病患者的临床及实验室数据资料,从中随机抽取10例具代表性、完善性的数据资料,然后使用超拉丁方抽样的方法对这些数据资料进行加工处理,得到一组全新的抽样数据。之后使用minitab软件工具对抽样数据作多元线性回归分析,得出同时具有医学意义和统计学意义的可靠结论。 展开更多
关键词 糖化血红蛋白 超拉丁方 相关系数 回归分析
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Role of Serum Procalcitonin Level in Differentiating between Pulmonary Tuberculosis and Community-Acquired Pneumonia 预览
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作者 Mohammad Shameem Mazhar Alam +3 位作者 Shagufta Moin Rakesh Bhargava Zuber Ahmad Jamal Akhtar 《临床医学国际期刊(英文)》 2014年第15期902-909,共8页
Pulmonary Tuberculosis (PTB) and Community-Acquired Pneumonia (CAP) are common causes of consolidation patch in chest radiograph. Sputum Z-N staining is positive in 30% to 60% cases only and sputum examination has poo... Pulmonary Tuberculosis (PTB) and Community-Acquired Pneumonia (CAP) are common causes of consolidation patch in chest radiograph. Sputum Z-N staining is positive in 30% to 60% cases only and sputum examination has poor yield in CAP. This study aimed to assess the value of serum Procalcitonin (PCT) levels in patients with Pulmonary Tuberculosis (PTB) and Community-Acquired Pneumonia (CAP). Patients with new opacity in chest radiograph were included in the study. Serum sample were taken at admission and stored. Patient’s diagnosis were confirmed and categorized into pulmonary TB group (32) and community-acquired pneumonia group (23). Their mean PCT level was compared with mean PCT level of 25 controls. Serum procalcitonin levels were found to be significantly elevated in patients of community-acquired pneumonia as compared to patients of pulmonary tuberculosis. In presence of consolidation in x-ray chest, increased level of serum procalcitonin might be used to differentiate pulmonary tuberculosis from community-acquired pneumonia. High level of serum procalcitonin was associated with high mortality rate in community-acquired pneumonia patients. 展开更多
关键词 PROCALCITONIN TUBERCULOSIS COMMUNITY-ACQUIRED PNEUMONIA
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Mental Health Literacy and the Belief in the Supernatural 预览
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作者 Leslie Lim Justine Goh +1 位作者 Yiong-Huak Chan Shi-Hui Poon 《精神病学期刊(英文)》 2015年第4期334-341,共8页
Objective: Mental health literacy affects treatment seeking. We compare literacy levels of psychiatric outpatients and a control group of outpatients seeking treatment for non-psychiatric disorders in the same hospita... Objective: Mental health literacy affects treatment seeking. We compare literacy levels of psychiatric outpatients and a control group of outpatients seeking treatment for non-psychiatric disorders in the same hospital. We hypothesized higher levels of mental health literacy among psychiatric patients than controls, with younger age and higher educational levels associated with better literacy. We also hypothesized that there would be an inverse relationship between educational level and the belief in the supernatural causality of mental disorders. Methods: Literacy was estimated by showing psychiatric outpatients and a control group of non-psychiatric patients vignettes depicting a case of major depression and a case of generalised anxiety disorder. Their opinions regarding diagnosis, etiology, treatment, and attitudes towards mental health services were ascertained by structured questionnaires. Results: Psychiatric patients did not demonstrate superior mental health literacy compared to controls, with the exception of knowing where to obtain a psychiatric referral. Lower age and higher education levels of psychiatric patients were associated with better literacy. The higher the education level is, the less likely to attribute the causality of mental disorders to supernatural elements. Conclusion: This study highlights the need for a program of psycho-education targeting patients, their relatives, and the public. 展开更多
关键词 MENTAL HEALTH LITERACY Age EDUCATION Level BELIEF in the SUPERNATURAL
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Pulmonary Fibrosis Due to Nitrofurantoin Therapy: A Case Report 预览
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作者 Leonidas Grigorakos Garyphallia Poulakou +5 位作者 Daria Lazarescu Pavlos Myrianthefs Nikolaos Markou Maria Bikou Adamantia Petineli Konstantinos Kokkinis 《呼吸病期刊(英文)》 2017年第3期117-124,共8页
We report the case of a patient with pulmonary fibrosis, developed as an adverse reaction to nitrofurantoin therapy received for totally 6 months for the prevention of recurrent urinary tract infections. Chest X-ray a... We report the case of a patient with pulmonary fibrosis, developed as an adverse reaction to nitrofurantoin therapy received for totally 6 months for the prevention of recurrent urinary tract infections. Chest X-ray and CT scan revealed extensive elements of interstitial pulmonary fibrosis. After diagnosis, administration of nitrofurantoin was immediately stopped;and specific prolonged therapy with low-dose corticosteroids per os and inhaled steroids were administered. The patient responded successfully both clinically and biochemically and possible digestive system side effects were prevented through the administration of gastroprotection medication. For the prevention of urinary tract infection, the patient received well tolerated therapy with fosfomycin which was further continued as a prophylactic agent. 展开更多
关键词 NITROFURANTOIN LUNG TOXICITY FIBROSIS FOSFOMYCIN
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Comparison of the Hypoglycemic, Hypolipidemic and Hepatoprotective Effects of<i>Asparagus racemosus</i>Linn. in Combination with Gliclazide and Pioglitazone on Alloxan-Induced Diabetic Rats 预览
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作者 Abdullah Al Mamun Mahbubul Hossain +8 位作者 Md. Sahab Uddin Md. Tanjir Islam Sajjad Hossain Md. Sarwar Hossain Md. Farhad Hossain Ataur Rahman Sujan Mamunur Rashid Md. Mahbubur Rahman A. F. M. Towheedur Rahman 《药理与制药(英文)》 2017年第2期52-74,共23页
In recent years, the popularity of medicinal plants as a remedy has been increased manifold due to having minimal adverse effects. The current study aimed to compare the hypoglycemic, hypolipidemic and hepatoprotectiv... In recent years, the popularity of medicinal plants as a remedy has been increased manifold due to having minimal adverse effects. The current study aimed to compare the hypoglycemic, hypolipidemic and hepatoprotective effects of the ethanolic extract of Asparagus racemosus (EEAR) Linn. alone and combinedly with conventional antidiabetic agents (gliclazide and pioglitazone) in alloxan-induced diabetic rats. Diabetes was induced in male Wister albino rats by the administration of single intra-peritoneal injection of alloxan monohydrate (120 mg/kg b.w.). Effect of oral administration of two different doses of EEAR (200 and 400 mg/kg b.w.), gliclazide (10 mg/kg b.w.) and pioglitazone (10 mg/70kg/b.w.) alone for 2 weeks and a combination of EEAR (200 mg/kg b.w.) with either gliclazide (10 mg/kg b.w.) or pioglitazone (10 mg/70kg/b.w.) for 2 weeks were examined on hypoglycemic activity on 0th, 5th, 10th and 14th day of treatment. After 2 weeks of treatment, hypolipidemic and hepatoprotective effects were estimated by serum biochemical markers such as total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), very low density lipoprotein (VLDL), high density lipoprotein (HDL), serum glutamate oxaloacetate transaminases (SGOT), serum glutamate pyruvate trans-aminases (SGPT) and total protein (TP) with the help of commercially available kits. The survival rate, body weight and organ weight were also measured. Alloxan treatment resulted in persistent hyperglycemia, hyperlipidemia and liver dysfunction in rats. Treatment with EEAR at different doses improved hyperglycemia significantly (p th and 14th day of treatment in a dose-dependent mood when compared to the disease control rats, gliclazide treated rats and pioglitazone treated rats. The combination therapy significantly (p th, 10th and 14th day of treatment as compared to that of disease control rats, gliclazide treated rats and pioglitazone treated rats. Proposed adjunct therapy also markedly (p < 0.001;p < 0.01, p < 0.001) improved serum TG, HDL and LD 展开更多
关键词 Diabetes Mellitus Asparagus racemosus GLICLAZIDE PIOGLITAZONE COMBINATION Therapy
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The Role of Color Doppler Ultrasound Arterial Mapping for Decision Making in the Treatment of Patients with Lower Extremity Peripheral Arterial Disease 预览
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作者 Ali Babaei Jandaghi Zahra Mardanshahi +5 位作者 Ahmad Alizadeh Iraj Baghi Hossein Hemmati Narges Tabarzan Baboli Shabnam Alizadeh Arasi Amin Keshavarzzirak 《外科学(英文)》 2013年第10期415-420,共6页
Purpose: To assess the efficacy of color Doppler imaging for decision making in the treatment of patients with lower extremity peripheral arterial disease (PAD) compared to digital subtraction angiography (DSA). Mater... Purpose: To assess the efficacy of color Doppler imaging for decision making in the treatment of patients with lower extremity peripheral arterial disease (PAD) compared to digital subtraction angiography (DSA). Materials and Methods: Color Doppler scan was done on patients suspected for lower limb PAD, a day prior to the DSA which was done by a vascular surgeon. Also, for the patients who were candidates for endovascular intervention based on the color Doppler arterial mapping results, endovascular interventions were performed at the same time if the DSA findings are correlated with the color Doppler map. The grading for evaluated segments was normal, insignificant stenosis (<50%), hemodynamically significant stenosis (≥50%) and occlusion. We yielded the diagnostic efficacy indices of Doppler for detecting arterial stenosis in each 18 different arterial segments below the renal arteries including, infrarenal aorta, common and external iliac, common femoral, superficial femoral (proximal, middle and distal segments), deep femoral, popliteal artery, tibioperoneal trunk, anterior and posterior tibial arteries (proximal, middle and distal segments) and peroneal artery (proximal and distal segments). Then, we yielded the kappa agreement between Doppler and DSA findings considering the grade of stenosis in 18 arterial segments separately. Results: Totally 115 lower extremities (2045 arterial segments) were evaluated in 90 patients [mean age: 60.8 ± 8.9 (range: 47 - 84 years old)] of which 68 (75.6%) were men. The sensitivity of color Doppler for all arterial segments was 90% or higher except for common iliac artery, distal segment of superficial femoral artery and proximal segments of anterior and posterior tibialis and peroneal arteries. However, the specificity was 89% or higher, in all arterial segments. Kappa agreement was 0.72 or higher in all segments (All P-Values 0.001). Conclusion: This study suggests that considering excellent capability of color Doppler sonography in the evaluation of lower extremity art 展开更多
关键词 Lower EXTREMITY Peripheral ARTERIAL Disease Color Doppler SONOGRAPHY ARTERIAL MAPPING Digital SUBTRACTION ANGIOGRAPHY
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Hepatitis B and Hepatitis C among Human Immunodeficiency Virus Infected Patients at a District Hospital in Mwanza, Tanzania 预览
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作者 Mariam M. Mirambo Benson R. Kidenya +7 位作者 Vitus Silago Emmanuel Mkumbo Awadh Mujuni Kennedy J. Mmanga Japhet J. Mwihambi Shimba Henerico Carolyne A. Minja Stephen E. Mshana 《艾滋病(英文)》 2019年第1期1-10,共10页
Human immunodeficiency virus (HIV), hepatitis B virus (HBV) and Hepatitis C virus (HCV) infections have been a major public health problem. HIV patients with HBV and HCV infection are at high risk of liver diseases wh... Human immunodeficiency virus (HIV), hepatitis B virus (HBV) and Hepatitis C virus (HCV) infections have been a major public health problem. HIV patients with HBV and HCV infection are at high risk of liver diseases which is associated with increased mortality. This study aims at determining the prevalence of hepatitis B surface antigen (HBsAg), HCV antibodies and HBV antibodies (anti-HBsAg) among HIV seropositive adults attending care and treatment clinic at Sengerema district hospital in Mwanza, Tanzania. A cross-sectional hospital based study was conducted between February and March 2017 among 243 HIV adult patients at Sengerema designated district hospital, Mwanza, Tanzania. Socio-demographic and other relevant information were collected using pre-tested questionnaires. Detection of HBsAg and HCV antibodies was done by commercial rapid immunochromatographic test while the detection of anti-HBsAg was done using enzyme linked immunosorbent assay. Data were analyzed by using STATA version 13. The median age of the study participants was 43, interquartile range (IQR): 37 - 51 years. The majority 172 (70.8) of study participants were female and the majority (88%) of participants had CD4 count of greater than 200 counts/μl. The prevalence of HBsAg, HCV antibodies and anti-HBsAg were 26/243 (10.7%, 95% confidence interval [CI]: 7 - 14), 20/243 (8.2%, 95% CI: 4.7 - 11.6) and (100/243) 41.2%, 95% CI: 35 - 47, respectively. Co-infection with HCV (OR: 4.45, 95% CI: 1.51 - 13.21, P = 0.007) was independenlty found to predict HbsAg positivity. History of blood transfusion (OR: 2.34, 95% CI: 1.08 - 5.06, P = 0.028) was significantly associated with anti-HBsAg among HIV infected individuals while, the rate of anti-HBsAg was found to decrease by 2.02 IU/L in a year increase in age. About one tenth of HIV infected individuals are co-infected with HCV and HBV with more than one third being positive for anti-HBsAg. There is a paramount need to emphasize the need for regular screening and proper management of these patients to r 展开更多
关键词 HEPATITIS B HEPATITIS C HIV Sengerema Tanzania
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Clinico-Angiographic Profile and Prevalence of Restenosis in Patients Undergoing Percutaneous Transluminal Coronary Angioplasty to Left Main Coronary Artery: An Observational Cohort Study 预览
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作者 Dolly Mathew C. G. Sajeev 《心血管病(英文)》 2017年第11期413-422,共10页
Background: Patients who underwent percutaneous coronary intervention in left main coronary artery (LMCA) requires special concern, being high risk and increasing patient population. The aim of this study was to asses... Background: Patients who underwent percutaneous coronary intervention in left main coronary artery (LMCA) requires special concern, being high risk and increasing patient population. The aim of this study was to assess the clinical profile, angiographic status, and prevalence of restenosis in patients who underwent percutaneous transluminal coronary angioplasty (PTCA) in LMCA. Materials and Methods: This observational cohort study included 17 patients who underwent PTCA in LMCA during one-year study period at tertiary care centers in Government Medical College, Kozhikode, India. Data including various risk factors, clinical and angiographic details, stent used, procedural complications and outcomes including rate of restenosis were analyzed. Results: A total of 17 patients (mean age 53.88 ± 9.80 years) with 76.47% of males were included in the study. Smoking and hypertension were the most common risk factors presented in 52.94% and 47.06% of patients respectively. Single vessel disease (SVD) of LMCA was the most common pattern observed in 47.10%;the rate of restenosis was observed in 11.76% patients. Revascularization was performed in one patient (5.88%) with coronary artery bypass graft and in one patient (5.88%) with PTCA using drug eluting stent (DES). The overall procedural success was 88.24% in this study. Survival rate was 100% at one-year follow-up period. Conclusion: Our study involved patients who underwent PTCA in LMCA, showed smoking as a most prevalent risk factor for coronary artery disease and SVD as a most common pattern, comparatively low rate of restenosis and 100% of survival rate at one-year follow-up period. 展开更多
关键词 CORONARY ARTERY Disease Drug Eluting Stent In-Stent RESTENOSIS Left Main CORONARY ARTERY Percutaneous TRANSLUMINAL CORONARY ANGIOPLASTY
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Temporal Trends in Radiation Dose Associated with Coronary Computed Tomography Angiography 预览
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作者 Paolo Marraccini Alessandro Mazzarisi +7 位作者 Clara Carpeggiani Mathis Schluter Marco Brambilla Massimiliano Bianchi Lorenzo Faggioni Giuseppe Coppini Carlo Bartolozzi Eugenio Picano 《放射学期刊(英文)》 2014年第1期101-110,共10页
Background: In 2010, the International Atomic Energy Agency launched the “3A’s campaign” as an effective tool for primary cancer prevention. In 2011, the American Association of Physicists in Medicine recommended t... Background: In 2010, the International Atomic Energy Agency launched the “3A’s campaign” as an effective tool for primary cancer prevention. In 2011, the American Association of Physicists in Medicine recommended the size specific dose estimate (SSDE). Objectives: To audit doses of Coronary CT Angiography (Coronary CTA) in tertiary care referral center. Methods: We reviewed 998 consecutive Coronary CTA (from 2007 to 2012). Doses (CTDIvol mGy), DLP (mGy*cm), effective dose (DLP*0.014, mSv) were on-line archived. SSDE was estimated retrospectively. Appropriateness score was evaluated for exams performed from the 2010. Results: Overall median dose per Coronary CTA was 49.7 mGy for CTDIvol, 55.5 mGy for SSDE, 994.96 mGy*cm for DLP, 13.9 mSv for effective dose. Median DLP decreased over time (1452.94 in 2007, 1605.56 in 2008, 1113.49 in 2009, 759.99 in 2010, 448.61 in 2011 and 497.88 mGy*cm in 2012, p < 0.0001). SSDE was proportional to the size dependent factor (SDF);in patients with SDF > 1 (88%) CTDIvol underestimated SSDE (48.49 vs 57.19 mGy), whilst in patients with SDF < 1 (12%) CTDIvol overestimated SSDE (56.46 vs 50.3 mGy). Scans were appropriate in 58%, uncertain in 24%, and inappropriate in 18% of cases. Doses were similar in appropriate, uncertain or inappropriate examinations and in excellent-to-good (81%) vs. sufficient-to-poor (19%) image quality exams. Conclusions: Coronary CTA reference doses can be very misleading. SSDE can allow individual technique optimization. The dose is similar in appropriate and inappropriate examinations, and unrelated to image quality. The rate of inappropriate examinations is still too high even after dissemination of guidelines. 展开更多
关键词 ISCHEMIC Heart Disease X RAY CARDIAC COMPUTED Tomography CARDIOVASCULAR Imaging Radiation DOSING
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Sodium Fluoride Induces Hepato-Renal Oxidative Stress and Pathophysiological Changes in Experimental Animals 预览
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作者 Azab Elsayed Azab Mohamed Omer Albasha +1 位作者 J. M. Jbireal Almokhtar A. Adwas 《细胞凋亡(英文)》 2018年第1期1-23,共23页
The liver is a primary site for xenobiotics detoxification, and its metabolism is readily altered by toxicity. The kidney is a common target for toxic xenobiotics due to its capacity to extract and concentrate toxic s... The liver is a primary site for xenobiotics detoxification, and its metabolism is readily altered by toxicity. The kidney is a common target for toxic xenobiotics due to its capacity to extract and concentrate toxic substances by highly specialized cells. So, they are the target organs of sodium fluoride toxicity. The aim of this review is to highlight on hepatorenal oxidative stress and pathophysiological changes induced by treatment of experimental animals with sodium fluoride. Our review shows fluoride toxicosis caused an elevation in the serum activities of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, lactate dehydrogenase, acid phosphatase, and the level of total bilirubin, and reduction in the serum levels of total protein, albumin, and globulins, and serious histopathological changes in the hepaic tissues. Also, NaF administration caused increases in serum urea, creatinine, uric acid, sodium ions, and chloride ions levels and serious histopathological changes in the kidney tissues. Treatment of experimental animals with NaF induced oxidative stress in hepatic and renal tissues. It can be concluded that administration of sodium fluoride to experimental animals induced oxidative stress, serious hepatorenal histopathological changes, and disturbance in liver and kidney functions. So, human should be advised to decrease exposure to sodium fluoride to decrease the harmful effects of NaF on liver and kidney. 展开更多
关键词 Sodium FLUORIDE TOXICITY Oxidative Stress Hepatorenal HISTOPATHOLOGICAL CHANGES Hepatorenal Pathophysiological CHANGES
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缬沙坦与氨氯地平联合治疗57例冠心病合并高血压的疗效 预览
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作者 任楼生 《临床研究》 2014年第12期76-76,共1页
目的:探讨缬沙坦、氨氯地平联合应用在57例冠心病合并高血压中的疗效。方法2012年1月到2014年7月我院共收治3113例冠心病合并高血压患者,并随机分为对照组(n=1556例)和观察组(n=1557)。给予对照组缬沙坦治疗,给予观察组缬沙坦、氨氯地... 目的:探讨缬沙坦、氨氯地平联合应用在57例冠心病合并高血压中的疗效。方法2012年1月到2014年7月我院共收治3113例冠心病合并高血压患者,并随机分为对照组(n=1556例)和观察组(n=1557)。给予对照组缬沙坦治疗,给予观察组缬沙坦、氨氯地平联合治疗,对比两组血压控制情况、心绞痛改善情况。结果治疗后观察组的DBP、SBP显著低于对照组(tDBP=43.396,P=0.000;tSBP=29.467,P=0.000)。对照组、观察组的心绞痛改善总有效率分别为86.8%、95.0%,观察组的总有效率显著高于对照组(X2总有效率=63.572,P=0.000)。结论联合应用缬沙坦、氨氯地平能够有效地控制血压,改善心绞痛病情,值得推广。 展开更多
关键词 缬沙坦 氨氯地平 冠心病合并高血压
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高龄老年COPD合并心绞痛采用比索洛尔治疗的临床效果分析 预览
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作者 郭辉 《临床研究》 2014年第4期92-92,共1页
目的:分析探讨高龄老年COPD合并心绞痛患者采用比索洛尔治疗的临床疗效。方法选取68例COPD合并心绞痛高龄老年患者作为研究对象,按照患者治疗方法将其分为研究组与对照组,对照组行常规治疗,研究组在常规治疗的基础上行比索洛尔治疗,比... 目的:分析探讨高龄老年COPD合并心绞痛患者采用比索洛尔治疗的临床疗效。方法选取68例COPD合并心绞痛高龄老年患者作为研究对象,按照患者治疗方法将其分为研究组与对照组,对照组行常规治疗,研究组在常规治疗的基础上行比索洛尔治疗,比较两组治疗效果。结果研究组治疗总有效率达94.1%,对照组治疗总有效率为79.4%,研究组治疗效果明显优于对照组(P<0.05);研究组治疗过程中出现的不良反应患者均可耐受,两组不良反应发生情况方面无显著差异(P>0.05)。结论对COPD合并心绞痛老年患者行比索洛尔治疗具有较为显著的有效性与安全性,可以推广应用。 展开更多
关键词 高龄 慢性阻塞性肺疾病 心绞痛 比索洛尔 疗效
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硝苯地平加美托洛尔治疗原发性高血压112例临床分析 预览
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作者 张建军 雷球英 《医学信息:医学与计算机应用》 2014年第20期228-228,共1页
目的探讨硝苯地平加美托洛尔在原发性高血压中的治疗效果。方法将我院2012年8月~2013年9月收治的224例原发性高血压患者随机分为观察组和对照组,对照组采用硝苯地平治疗,观察组在对照组的基础上采用美托洛尔治疗,比较两组的治疗效果及... 目的探讨硝苯地平加美托洛尔在原发性高血压中的治疗效果。方法将我院2012年8月~2013年9月收治的224例原发性高血压患者随机分为观察组和对照组,对照组采用硝苯地平治疗,观察组在对照组的基础上采用美托洛尔治疗,比较两组的治疗效果及不良反应。结果观察组的总有效率为87.5%高于对照组的72.3%,治疗的收缩压和舒张压低于对照组,不良反应少于对照组,有统计学意义(<0.05)。结论硝苯地平加美托洛尔能够显著提高原发性高血压的治疗效果,并能有效减少不良反应,值得推广。 展开更多
关键词 硝苯地平 美托洛尔 原发性高血压 治疗
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盐敏感性老年高血压患者低盐饮食认知调查及健康教育 预览
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作者 李桂珍 《医学信息:医学与计算机应用》 2014年第24期412-413,共2页
盐敏感性高血压定义为相对高盐摄入所引起的血压升高,盐敏感者在高血压人群中为28%~74%[1]。高盐饮食是高血压发病的重要危险因素,膳食钠盐摄入量平均增加2g/d收缩压和舒张压分别增高2.0mmHg和1.2mmHg。特别是盐敏感老年高血压患者,为... 盐敏感性高血压定义为相对高盐摄入所引起的血压升高,盐敏感者在高血压人群中为28%~74%[1]。高盐饮食是高血压发病的重要危险因素,膳食钠盐摄入量平均增加2g/d收缩压和舒张压分别增高2.0mmHg和1.2mmHg。特别是盐敏感老年高血压患者,为了有效地防治高血压,我卫生服务中心采用自制的调查问卷,对辖区内的300例盐敏感性老年高血压患者低进行低盐饮食认知情况调查,现报道如下。 展开更多
关键词 盐敏感性高血压 老年 高血压患者 低盐饮食 认知调查 卫生服务中心 认知情况调查 现报道如下 盐摄入量 血压升高 危险因素 高盐饮食 高盐摄入 调查问卷 舒张压 收缩压 自制 辖区 膳食 人群
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烧伤后肠道屏障功能障碍与防治措施 预览 被引量:1
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作者 王来红 《医学信息:医学与计算机应用》 2014年第10期500-501,共2页
长期以来,人们对肠道功能的认识仅局限于它是一个消化器官。在烧(创)伤、感染等所致危重病的救治中,临床医生的注意力多集中在心、肺、肾等脏器,而忽视了肠道屏障功能在危重症发生、发展中的作用。20世纪80年代以来,随着临床营养学和危... 长期以来,人们对肠道功能的认识仅局限于它是一个消化器官。在烧(创)伤、感染等所致危重病的救治中,临床医生的注意力多集中在心、肺、肾等脏器,而忽视了肠道屏障功能在危重症发生、发展中的作用。20世纪80年代以来,随着临床营养学和危重症医学的发展,关于肠道在调节机体代谢及营养中的作用,特别是肠道屏障功能等方面的知识也在不断丰富,并逐渐形成新的观点:肠道不仅是消化和吸收营养素的器官,也是阻止肠腔内细菌、毒素等有害物质侵入体内的重要屏障,以及调控机体应激反应、生成炎症介质的重要器官,在MODS的发生、发展中起重要作用。基于此点,国内外不少学者相继提出'肠源性感染'、'在病理状态下肠道是一个未获引流的脓肿'、'肠道是外科应激的中心器官'等观点,并推论肠道可能成为MODS的启动器官。现结合国内外文献的相关研究报道,从不同侧面研究了烧伤后肠道屏障的变化、发生机制及防治策略,对此作一阐述。 展开更多
关键词 烧伤 后肠道 屏障功能障碍 肠道屏障 重要器官 临床营养学 危重症医学 机体应激反应 肠源性感染 有害物质 炎症介质 消化器官 相关研究 外科应激 临床医生 机体代谢 国内 防治策略 发生机制 肠道功能
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阿托伐他汀治疗对急性冠脉综合征患者血清sCD40、sCD40L和MMP-9的影响 预览
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作者 陈芳 《医学信息:医学与计算机应用》 2014年第10期168-169,共2页
目的:探讨急性冠脉综合征患者血清血清sCD40、sCD40L和MMP-9的变化,以及阿托伐他汀治疗对其的影响,初步探讨阿托伐他汀对急性冠脉综合征的预防与治疗机制。方法将120例急性冠脉综合征患者随机分为A组(n=60)和B组(n=60),A组常规治疗,B组... 目的:探讨急性冠脉综合征患者血清血清sCD40、sCD40L和MMP-9的变化,以及阿托伐他汀治疗对其的影响,初步探讨阿托伐他汀对急性冠脉综合征的预防与治疗机制。方法将120例急性冠脉综合征患者随机分为A组(n=60)和B组(n=60),A组常规治疗,B组在常规治疗基础上加服阿托伐他汀,在治疗前后分别测定每组患者血清sCD40、sCD40L和MMP-9水平。结果急性冠脉综合征血清sCD40、sCD40L和MMP-9水平较对照组显著升高(P<0.05);B组治疗后较治疗前及A组治疗后血清sCD40、sCD40L和MMP-9显著降低(P<0.05),A 组治疗前后血清sCD40、sCD40L和MMP-9差异无统计学意义(P>0.05)。结论血清sCD40、sCD40L和MMP-9可能与急性冠脉综合征发生发展有关,阿托伐他汀能显著降低急性冠脉综合征患者 sCD40、sCD40L和MMP-9水平,治疗急性冠脉综合征的机制可能与调节血清sCD40、sCD40L和MMP-9水平有关。 展开更多
关键词 阿托伐他汀 急性冠脉综合征 SCD40L MMP-9
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上消化道出血的诊断与治疗 预览 被引量:2
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作者 林政章 《医学信息:医学与计算机应用》 2014年第17期511-511,共1页
目的:探讨上消化道出血的诊断方式与治疗方法。方法通过对60例上消化道出血患者的临床观察,分析和总结所运用的诊断方式与治疗方法。结果十二指肠球部溃疡是导致上消化道出血的主要原因。胃溃疡、肝硬化、Mal ory-Weiss 综合征、急性胃... 目的:探讨上消化道出血的诊断方式与治疗方法。方法通过对60例上消化道出血患者的临床观察,分析和总结所运用的诊断方式与治疗方法。结果十二指肠球部溃疡是导致上消化道出血的主要原因。胃溃疡、肝硬化、Mal ory-Weiss 综合征、急性胃粘膜病是导致上消化道出血的重要原因;胃镜检查是安全的,内镜诊断检查率逐年增加。结论上消化道出血发病机理各种各样,治疗手段也与时俱进,应该采用积极综合的办法做出正确诊断、迅速治疗抢救患者生命。 展开更多
关键词 上消化道出血 临床表现 诊断 治疗
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有创序贯无创机械通气配合中医药治疗慢性阻塞性肺疾病急性呼吸衰竭临床观察 预览 被引量:1
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作者 要莉莉 贾丽静 +1 位作者 提长斌 马增香 《文摘版:医药卫生》 2015年第12期114-114,共1页
目的:观察有创序贯无创机械通气配合中医药治疗慢性阻塞性肺疾病(COPD)急性呼吸衰竭临床疗效。方法:选择我院收治的符合条件的COPD急性呼吸衰竭患者27例,随机分为实验组和对照组,实验组18例,对照组9例。两组患者采用有创序贯无... 目的:观察有创序贯无创机械通气配合中医药治疗慢性阻塞性肺疾病(COPD)急性呼吸衰竭临床疗效。方法:选择我院收治的符合条件的COPD急性呼吸衰竭患者27例,随机分为实验组和对照组,实验组18例,对照组9例。两组患者采用有创序贯无创机械通气的方法进行治疗,实验组在此基础上配合中医辨证理论进行治疗。比较实验组和对照组通气及血氧饱和度、肺部感染出现时间、有创通气时间、机械通气总时间、ICU住院时间、重新气管插管例数、撤机例数、死亡例数。结果:实验组患者拔管3h后能维持良好通气指标,与治疗前无显著性差异(P>0.05)。治疗组出现肺部感染的时间与对照组相比有所减少,(P<0.05);患者通气、心率指标均比机械通气前有所好转,两组间各指标差异不明显(P>0.05)。实验组有创机械通气时间和机械通气总时间、ICU住院时间比对照组明显缩短(P<0.05)。 结论:有创序贯无创机械通气配合中医药治疗慢性阻塞性肺疾病急性呼吸衰竭能改善通气效率,能在较短的时间内控制肺部感染,缩短机械通气总时间及ICU住院观察时间,临床疗效显著。 展开更多
关键词 慢性阻塞性肺疾病 机械通气 中医药治疗 序贯治疗
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阿托伐他汀钙片降脂疗效的临床观察 预览
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作者 田洪宇 《医药界》 2019年第19期0045-0045,共1页
目的:观察阿托伐他汀钙片对高脂血患者的治疗效果。方法:随机从 2018 年 1 月至 2018 年 9 月来我院进行高脂血治疗的患者中抽取 50 例,随机分为对照组和研究组,研究 组的 25 例患者在服用硝酸脂类、β- 受体阻滞剂和抗血小板药物的基础... 目的:观察阿托伐他汀钙片对高脂血患者的治疗效果。方法:随机从 2018 年 1 月至 2018 年 9 月来我院进行高脂血治疗的患者中抽取 50 例,随机分为对照组和研究组,研究 组的 25 例患者在服用硝酸脂类、β- 受体阻滞剂和抗血小板药物的基础上,服用阿托伐他汀钙片;对照组的 25 例患者只使用硝酸脂类、β- 受体阻滞剂和抗血小板药物,进而比较两组 患者的血脂情况。结果:通过对两组患者进行治疗观察,表明研究组的血脂情况有明显的改善,对照组患者的血脂情况没有明显的变化。结论:阿托伐他汀钙片在治疗高脂血疾病中有 明显的疗效,副作用比较小,可以在临床中大力推广和应用。 展开更多
关键词 阿托伐他汀钙片 高脂血 强效降脂 疗效
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