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Impact of continuous local lavage on pancreatic juice-related postoperative complications:Three case reports 预览
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作者 Tomohide Hori Kohei Ogawa +16 位作者 Hidekazu Yamamoto Hideki Harada Kazuyoshi Matsumura Michihiro Yamamoto Masahiro Yamada Takefumi Yazawa Katsutoshi Kuriyama Masaki Tani Daiki Yasukawa Yasuyuki Kamada Yuki Aisu Ryotaro Tani Ryuhei Aoyama Shinnosuke Nakayama Yudai Sasaki Koki Nishimoto Masazumi Zaima 《世界临床病例杂志》 2019年第17期2526-2535,共10页
BACKGROUND Postoperative pancreatic leakage readily results in intractable pancreatic fistula and subsequent intraperitoneal abscess.This refractory complication can be fatal;therefore,intensive treatment is important... BACKGROUND Postoperative pancreatic leakage readily results in intractable pancreatic fistula and subsequent intraperitoneal abscess.This refractory complication can be fatal;therefore,intensive treatment is important.Continuous local lavage (CLL) has recently been reevaluated as effective treatment for severe infected pancreatitis,and we report three patients with postoperative intractable pancreatic fistula successfully treated by CLL.We also discuss our institutional protocol for CLL for postoperative pancreatic fistula.CASE SUMMARY The first patient underwent subtotal stomach-preserving pancreaticoduodenectomy,and pancreatic leakage was observed postoperatively.Intractable pancreatic fistula led to intraperitoneal abscess,and CLL near the pancreaticojejunostomy site was instituted from postoperative day (POD) 8.The abscess resolved after 7 d of CLL.The second patient underwent distal pancreatectomy.Pancreatic leakage was observed,and intractable pancreatic fistula led to intraperitoneal abscess near the pancreatic stump.CLL was instituted from POD 9,and the abscess resolved after 4 d of CLL.The third patient underwent aneurysmectomy and splenectomy with wide exposure of the pancreatic parenchyma.Endoscopic retrograde pancreatic drainage was performed on POD 15 to treat pancreatic fistula;however,intraperitoneal abscess was detected on POD 59.We performed CLL endoscopically via the transgastric route because the percutaneous approach was difficult.CLL was instituted from POD 63,and the abscess resolved after 1 wk of CLL.CONCLUSION CLL has therapeutic potential for postoperative pancreatic fistula. 展开更多
关键词 Surgery PANCREAS PANCREATIC FISTULA PANCREATIC JUICE POSTOPERATIVE complications Case report
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Temporal adjustment of short calls according to a partner during vocal turn-taking in Japanese macaques
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作者 Noriko KATSu Kazunori Yamada +1 位作者 Kazuo Okanoya Masayuki Nakamichi 《动物学报:英文版》 SCIE CAS CSCD 2019年第1期99-105,共7页
Turn-taking is a common feature in human speech, and is also seen in the communication of other primate species. However, evidenee of turn-taking in vocal exchanges within a short time frame is still scarce in non hum... Turn-taking is a common feature in human speech, and is also seen in the communication of other primate species. However, evidenee of turn-taking in vocal exchanges within a short time frame is still scarce in non human primates. This study in vestigated whether dynamic adjustme nt during turn-taking in short calls exists in Japanese macaques Macaca fuscata. We observed exchanges of short calls such as grunts, girneys, and short, low coos during social interactions in a free-ranging group of Japanese macaques. We found that the median gap between the turns of two callers was 250 ms. Call intervals varied among individuals, suggesting that call intervals were not fixed among individuals. Solo call intervals were shorter than call intervals interrupted by responses from partn ers (i.e., excha nges) and Ion ger than those between the partner's reply and the reply to that call, indicating that the monkeys did not just repeat calls at certain intervals irrespective of the social situation. The differences in call intervals during exchanged and solo call sequences were explained by the response interval of the partner, suggesting an adjustment of call timing according to the tempo of the part ner's call utterance. These findi ngs suggest that mon keys display dyn amic temporal adjustment in a short time window, which is comparable with turn-taking in human speech. 展开更多
关键词 TURN-TAKING RHYTHM VOCALIZATION PRIMATE
Management of the late effects of disconnected pancreatic duct syndrome: A case report 预览
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作者 Reiko Yamada Yuhei Umeda +8 位作者 Yasunori Shiono Hiroaki Okuse Naoki Kuroda Junya Tsuboi Hiroyuki Inoue Yasuhiko Hamada Kyosuke Tanaka Noriyuki Horiki Yoshiyuki Takei 《世界临床病例杂志》 2019年第9期1053-1059,共7页
BACKGROUND There have been few reports about the late effects of disconnected pancreatic duct syndrome (DPDS). Although few reports have described the recurrence interval of pancreatitis, it might be rare for recurren... BACKGROUND There have been few reports about the late effects of disconnected pancreatic duct syndrome (DPDS). Although few reports have described the recurrence interval of pancreatitis, it might be rare for recurrence to occur more than 5 years later. Herein, we describe a case of recurrence in an 81-year-old man after the treatment of walled-off necrosis (WON) with pancreatic transection 7 years ago. CASE SUMMARY An 81-year-old man visited our hospital with chief complaints of fever and abdominal pain 7 years after the onset of WON due to severe necrotic pancreatitis. His medical history included an abdominal aortic aneurysm (AAA), hypertension, dyslipidemia, and chronic kidney disease. Computed tomography (CT) scan showed that the pancreatic fluid collection (PFC) had spread to the aorta with inflammation surrounding it, and CT findings suggested that bleeding occurred from the vasodilation due to splenic vein occlusion. First, we attempted to perform transpapillary drainage because of venous dilation around the residual stomach and the PFC. However, pancreatic duct drainage failed because of complete main pancreatic duct disruption. Second, we performed endoscopic ultrasound-guided drainage. After transmural drainage, the inflammation improved and stenting for the AAA was performed successfully. The inflammation was resolved, and he has been free from infection for more than 2 years after the procedure. CONCLUSION This case highlights the importance of continued follow-up of patients for recurrence after the treatment of WON with pancreatic transection. 展开更多
关键词 Case report ENDOSCOPY NECROSIS PANCREAS Walled-off NECROSIS Disconnected PANCREATIC DUCT SYNDROME
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A patient presenting painful chest wall swelling:Tietze syndrome 预览
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作者 Kohei Sawada Hiromi Ihoriya +5 位作者 Taihei Yamada Tetsuya Yumoto Kohei Tsukahara Takaaki Osako Hiromichi Naito Atsunori Nakao 《世界急诊医学杂志(英文)》 CAS CSCD 2019年第2期122-124,共3页
Dear editor,Patients frequently visit the emergency room with acute chest pain.While some potentially life-threatening disorders may cause the pain,in approximately 80%of cases,the chest pain source is benign,and musc... Dear editor,Patients frequently visit the emergency room with acute chest pain.While some potentially life-threatening disorders may cause the pain,in approximately 80%of cases,the chest pain source is benign,and musculoskeletal chest pain accounts for nearly 20%– 50%of those cases.^[1–6]Thus,pain caused by benign and pathological conditions of the chest wall encountered in the emergency department is sometimes incorrectly attributed to angina pectoris or pleuritic and other serious cardiopulmonary diseases. 展开更多
关键词 Patients frequently EMERGENCY ROOM LIFE-THREATENING
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ViVi NIGHT IN TOKYO 2018
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作者 Tatsuyo Hamamura(图) Tohru Daimon(图) Yurin Yamada 《美眉》 2019年第1期160-161,共2页
10月23号在豊洲PIT举办的ViVi NIGHT的report.fan meeting、人气选手MILK的SP LIVE,还有世界第一可爱的ViVi的模特们的fashion show盛大举行.还有最后玲奈和Tina在晚宴上的毕业发言让人流泪……
关键词 流泪 世界 毕业 晚宴 人气
Initial management for acute lower gastrointestinal bleeding 预览
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作者 Tomonori Aoki Yoshihiro Hirata +1 位作者 Atsuo Yamada Kazuhiko Koike 《世界胃肠病学杂志:英文版》 SCIE CAS 2019年第1期69-84,共16页
Acute lower gastrointestinal bleeding(LGIB)is a common indication for hospital admission.Patients with LGIB often experience persistent or recurrent bleeding and require blood transfusions and interventions,such as co... Acute lower gastrointestinal bleeding(LGIB)is a common indication for hospital admission.Patients with LGIB often experience persistent or recurrent bleeding and require blood transfusions and interventions,such as colonoscopic,radiological,and surgical treatments.Appropriate decision-making is needed to initially manage acute LGIB,including emergency hospitalization,timing of colonoscopy,and medication use.In this literature review,we summarize the evidence for initial management of acute LGIB.Assessing various clinical factors,including comorbidities,medication use,presenting symptoms,vital signs,and laboratory data is useful for risk stratification of severe LGIB,and for discriminating upper gastrointestinal bleeding.Early timing of colonoscopy had the possibility of improving identification of the bleeding source,and the rate of endoscopic intervention,compared with elective colonoscopy.Contrast-enhanced computed tomography before colonoscopy may help identify stigmata of recent hemorrhage on colonoscopy,particularly in patients who can be examined immediately after the last hematochezia.How to deal with nonsteroidal antiinflammatory drugs(NSAIDs)and antithrombotic agents after hemostasis should be carefully considered because of the risk of rebleeding and thromboembolic events.In general,aspirin as primary prophylaxis for cardiovascular events and NSAIDs were suggested to be discontinued after LGIB.Managing acute LGIB based on this information would improve clinical outcomes.Further investigations are needed to distinguish patients with LGIB who require early colonoscopy and hemostatic intervention. 展开更多
关键词 Lower GASTROINTESTINAL BLEEDING PREDICTIVE model COLONOSCOPY COMPUTED tomography MEDICATION
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Colon perforation due to antigenemia-negative cytomegalovirus gastroenteritis after liver transplantation: A case report and review of literature 预览
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作者 Takahiro Yokose Hideaki Obara +19 位作者 Masahiro Shinoda Yutaka Nakano Minoru Kitago Hiroshi Yagi Yuta Abe Yohei Yamada Kentaro Matsubara Go Oshima Shutaro Hori Sho Ibuki Hisanobu Higashi Yuki Masuda Masanori Hayashi Takehiko Mori Miho Kawaida Takumi Fujimura Ken Hoshino Kaori Kameyama Tatsuo Kuroda Yuko Kitagawa 《世界胃肠病学杂志:英文版》 SCIE CAS 2019年第15期1899-1906,共8页
BACKGROUND Cytomegalovirus (CMV) remains a critical complication after solid-organ transplantation. The CMV antigenemia (AG) test is useful for monitoring CMV infection. Although the AG-positivity rate in CMV gastroen... BACKGROUND Cytomegalovirus (CMV) remains a critical complication after solid-organ transplantation. The CMV antigenemia (AG) test is useful for monitoring CMV infection. Although the AG-positivity rate in CMV gastroenteritis is known to be low at onset, almost all cases become positive during the disease course. We treated a patient with transverse colon perforation due to AG-negative CMV gastroenteritis, following a living donor liver transplantation (LDLT). CASE SUMMARY The patient was a 52-year-old woman with decompensated liver cirrhosis as a result of autoimmune hepatitis who underwent a blood-type compatible LDLT with her second son as the donor. On day 20 after surgery, upper and lower gastrointestinal endoscopy (GE) revealed multiple gastric ulcers and transverse colon ulcers. The biopsy tissue immunostaining confirmed a diagnosis of CMV gastroenteritis. On day 28 after surgery, an abdominal computed tomography revealed transverse colon perforation, and simple lavage and drainage were performed along with an urgent ileostomy. Although the repeated remission and aggravation of CMV gastroenteritis and acute cellular rejection made the control of immunosuppression difficult, the upper GE eventually revealed an improvement in the gastric ulcers, and the biopsy samples were negative for CMV. The CMV-AG test remained negative, therefore, we had to evaluate the status of the CMV infection on the basis of the clinical symptoms and GE. CONCLUSION This case report suggests a monitoring method that could be useful for AGnegative CMV gastroenteritis after a solid-organ transplantation. 展开更多
关键词 CYTOMEGALOVIRUS gastrointestinal disease COLON PERFORATION ANTIGENEMIA negative Liver transplantation Case report
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Glutamine or Glutamine Dipeptide Supplementation Improves Gluconeogenesis and Liver Glycogenosis in Type 1 Diabetic Rats 预览
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作者 Silvia Carla S.F.Azevedo Carlos Vinicius D.da Rosa +10 位作者 Ana Luiza M.Wunderlich Laís A.Yamada Isabela R.Mariano Camila Bataglini Nayra T.D.Branquinho Scarlett R.Raposo Roberto B.Bazotte Edmara A.Baroni Maria Raquel M.Natali Maria Montserrat D.Pedrosa Vilma A.F.de Godoi 《药剂与药理学:英文版》 2019年第7期398-407,共10页
The effects of the supplementation with L-glutamine(GLN)or L-alanyl-L-glutamine(GDP)on the progression of the systemic and hepatic metabolic status of rats having untreated type 1 diabetes mellitus(T1DM)were investiga... The effects of the supplementation with L-glutamine(GLN)or L-alanyl-L-glutamine(GDP)on the progression of the systemic and hepatic metabolic status of rats having untreated type 1 diabetes mellitus(T1DM)were investigated.Male Wistar diabetic rats(streptozotocin,60 mg/kg)were allotted to four groups supplemented by gavage for thirty days as follows:control and diabetic receiving saline;diabetic receiving GLN(248 mg/kg);and diabetic receiving GDP(400 mg/kg).Body weight,plasmatic parameters and kidney function were analyzed.Isolated hepatocytes were used to assess gluconeogenic capacity.Liver and kidney were used for morphological analyses.T1DM decreased the number and increased the area of the hepatocytes,possibly because of the observed enlargement of glycogen stores.Kidney weight,glomerular area and proteinuria increased,and glomerular filtration rate decreased,in non-supplemented T1DM rats.Glomerular area and proteinuria were reversed by both supplementations.The T1DM hepatocytes released less glucose,which could have been diverted to glycogen synthesis and secondary glycogenosis observed in T1DM;this was partially reversed by the supplementations.The results point to a possible beneficial effect of glutamine on the metabolic and hepatic impairments of T1DM. 展开更多
关键词 TYPE 1 diabetes mellitus L-GLUTAMINE GLUTAMINE DIPEPTIDE GLUCONEOGENESIS GLYCOGENOSIS
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Clinical outcomes of ampullary neoplasms in resected margin positive or uncertain cases after endoscopic papillectomy 预览
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作者 Arata Sakai Masahiro Tsujimae +16 位作者 Atsuhiro Masuda Takao Iemoto Shigeto Ashina Kohei Yamakawa Takeshi Tanaka Shunta Tanaka Yasutaka Yamada Ryota Nakano Yu Sato Manabu Kurosawa Takuya Ikegawa Seiji Fujigaki Takashi Kobayashi Hideyuki Shiomi Yoshifumi Arisaka Tomoo Itoh Yuzo Kodama 《世界胃肠病学杂志:英文版》 SCIE CAS 2019年第11期1387-1397,共11页
BACKGROUND Endoscopic papillectomy(EP) for benign ampullary neoplasms could be a lessinvasive alternative to pancreatoduodenectomy(PD). There are some problems and limitations with EP. The post-EP resection margins of... BACKGROUND Endoscopic papillectomy(EP) for benign ampullary neoplasms could be a lessinvasive alternative to pancreatoduodenectomy(PD). There are some problems and limitations with EP. The post-EP resection margins of ampullary tumors are often positive or uncertain because of the burning effect of EP. The clinical outcomes of resected margin positive or uncertain cases after EP remain unknown.AIM To investigate the clinical outcomes of resected margin positive or uncertain cases after EP.METHODS Between January 2007 and October 2018, all patients with ampullary tumors who underwent EP at Kobe University Hospital were included in this study. The indications for EP were as follows: adenoma, as determined by preoperative endoscopic biopsy, without bile/pancreatic duct extension, according to endoscopic ultrasound or intraductal ultrasound. The clinical outcomes of resected margin positive or uncertain cases after EP were retrospectively investigated.RESULTS Of the 45 patients, 29 were male, and 16 were female. The mean age of the patients was 65 years old. Forty-one patients(89.5%) underwent en bloc resection,and 4 patients(10.5%) underwent piecemeal resection. After EP, 33 tumors were histopathologically diagnosed as adenoma, and 12 were diagnosed as adenocarcinoma. The resected margins were positive or uncertain in 24 patients(53.3%). Of these cases, 15 and 9 were diagnosed as adenoma and adenocarcinoma, respectively. Follow-up observation was selected for all adenomas and 5 adenocarcinomas. In the remaining 4 adenocarcinoma cases,additional PD was performed. Additional PD was performed in 4 cases, and residual carcinoma was found after the additional PD in 1 of these cases. In the follow-up period, local tumor recurrence was detected in 3 cases. Two of these cases involved primary EP-diagnosed adenoma. The recurrent tumors were also adenomas detected by biopsy. The remaining case involved primary EPdiagnosed adenocarcinoma. The recurrent tumor was also an adenocarcinoma.All of the recurrent tumors were successfu 展开更多
关键词 Ampullary NEOPLASM ENDOSCOPIC PAPILLECTOMY Resected MARGIN Clinical OUTCOME
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A Fundamental Study on Multi-agent Pedestrian Model Based on Risk Avoidance Behavior during Road Blockage and Evacuation Simulation of Regional Urban Disaster 预览
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作者 Hideaki Takayanagi Tatsuto Kihara +5 位作者 Yosuke Kurita Kazuhide Kawaguchi Hidetoshi Kawaguchi Takaaki Furukawa Takuhi Ono Shogo Yamada 《土木工程与建筑:英文版》 2019年第4期219-237,共19页
Regional cities in Japan are at the risk of experiencing big fire accidents or earthquakes every day.However,neither the number nor the capacity of shelters has increased because local governments might not consider t... Regional cities in Japan are at the risk of experiencing big fire accidents or earthquakes every day.However,neither the number nor the capacity of shelters has increased because local governments might not consider them owing to budget shortfall.By contrast,wide-area evacuation simulations can easily provide an antagonizing image of regional urban disasters.After a disaster,the city collapses and the evacuation routes are closed;consequently,evacuees feel anxious and they cannot move as usual.This anxiety behavior has not been considered in previous related studies and simulations.In this study,a wide-area evacuation simulation is developed;this model can not only calculate the possibility of blocking escape routes when the city is broken but also provide safe and more realistic evacuation plans before a disaster occurs by incorporating into the simulation the risk avoidance behaviors of evacuees from road blockage,such as“the route re-seeking behavior”and“the shelter re-selecting behavior”. 展开更多
关键词 Wide-area EVACUATION simulation MULTI-AGENT model risk AVOIDANCE BEHAVIOR regional DISASTER prevention plan
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Z-bpy,a New C2-Symmetric Bipyridine Ligand and Its Application in Enantioselective Copper(Ⅰ)-Catalyzed Cyclopropanation of Olefins
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作者 Yizhao Ouyang Miao Zhan +4 位作者 Jing Zhou Jiao Jiao Hao HU Yoichi M.A.Yamada Pengfei Li 《中国化学:英文版》 SCIE CAS CSCD 2019年第8期807-810,共4页
Summary of main observation and conclusion A rigid C2-symmetric chiral bipyridine ligand Z-bpy with a triptycene-like backbone was designed and synthesized from simple chemicals in a scalable route.Using this new liga... Summary of main observation and conclusion A rigid C2-symmetric chiral bipyridine ligand Z-bpy with a triptycene-like backbone was designed and synthesized from simple chemicals in a scalable route.Using this new ligand,copper(Ⅰ) catalyzed cyclopropanation of styrenes with commercial ethyl diazoacetate produced various corresponding cyclopropanes in high yields,diastereoselectivity and enantioselectivity up to 97% ee. 展开更多
关键词 ITS was
Model combining pre-transplant tumor biomarkers and tumor size shows more utility in predicting hepatocellular carcinoma recurrence and survival than the BALAD models 预览
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作者 Nicha Wongjarupong Gabriela M Negron-Ocasio +17 位作者 Roongruedee Chaiteerakij Benyam D Addissie Essa A Mohamed Kristin C Mara William S Harmsen J Paul Theobald Brian E Peters Joseph G Balsanek Melissa M Ward Nasra H Giama Sudhakar K Venkatesh Denise M Harnois Michael R Charlton Hiroyuki Yamada Alicia Algeciras-Schimnich Melissa R Snyder Terry M Therneau Lewis R Roberts 《世界胃肠病学杂志:英文版》 SCIE CAS 2018年第12期1321-1331,共11页
AIM To assess the performance of BALAD,BALAD-2 and their component biomarkers in predicting outcome of hepatocellular carcinoma(HCC)patients after liver transplant.METHODS BALAD score and BALAD-2 class are derived fro... AIM To assess the performance of BALAD,BALAD-2 and their component biomarkers in predicting outcome of hepatocellular carcinoma(HCC)patients after liver transplant.METHODS BALAD score and BALAD-2 class are derived from bilirubin,albumin,alpha-fetoprotein(AFP),Lens culinaris agglutinin-reactive AFP(AFP-L3),and des-gammacarboxyprothrombin(DCP).Pre-transplant AFP,AFP-L3 and DCP were measured in 113 patients transplanted for HCC from 2000 to 2008.Hazard ratios(HR)for recurrence and death were calculated.Univariate and multivariate regression analyses were conducted.C-statistics were used to compare biomarker-based to predictive models.RESULTS During a median follow-up of 12.2 years,38 patients recurred and 87 died.The HRs for recurrence in patients with elevated AFP,AFP-L3,and DCP defined by BALAD cut-off values were 2.42(1.18-5.00),1.86(0.98-3.52),and 2.83(1.42-5.61),respectively.For BALAD,the HRs for recurrence and death per unit increased score were 1.48(1.15-1.91)and 1.59(1.28-1.97).For BALAD-2,the HRs for recurrence and death per unit increased class were 1.45(1.06-1.98)and 1.38(1.09-1.76).For recurrence prediction,the combination of three biomarkers had the highest c-statistic of 0.66 vs.0.64,0.61,0.53,and 0.53 for BALAD,BALAD-2,Milan,and UCSF,respectively.Similarly,for death prediction,the combination of three biomarkers had the highest c-statistic of 0.66 vs 0.65,0.61,0.52,and 0.50 for BALAD,BALAD-2,Milan,and UCSF.A new model combining biomarkers with tumor size at the time of transplant(S-LAD)demonstrated the highest predictive capability with c-statistics of 0.71 and 0.69 for recurrence and death.CONCLUSION BALAD and BALAD-2 are valid in transplant HCC patients,but less predictive than the three biomarkers in combination or the three biomarkers in combination with maximal tumor diameter(S-LAD). 展开更多
关键词 alpha-fetoprotein AFP-L3 des-gammacarboxyprothrombin BALAD BALAD-2 Hepatocellular carcinoma Liver TRANSPLANT RECURRENCE Outcome
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Sessile serrated adenoma detection rate is correlated with adenoma detection rate 预览
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作者 Daisuke Ohki Yosuke Tsuji +15 位作者 Tomohiro Shinozaki Yoshiki Sakaguchi Chihiro Minatsuki Hiroto Kinoshita Keiko Niimi Satoshi Ono Yoku Hayakawa Shuntaro Yoshida Atsuo Yamada Shinya Kodashima Nobutake Yamamichi Yoshihiro Hirata Tetsuo Ushiku Mitsuhiro Fujishiro Masashi Fukayama Kazuhiko Koike 《世界胃肠肿瘤学杂志:英文版(电子版)》 CAS 2018年第3期82-90,共9页
AIM To investigated the association between adenoma detection rate(ADR)and sessile serrated ADR(SSADR)and significant predictors for sessile serrated adenomas(SSA)detection.METHODS This study is a retrospective,single... AIM To investigated the association between adenoma detection rate(ADR)and sessile serrated ADR(SSADR)and significant predictors for sessile serrated adenomas(SSA)detection.METHODS This study is a retrospective,single-center analysis.Total colonoscopies performed by the gastroenterologists at the University of Tokyo Hospital between January and December 2014 were retrospectively identified.Polyps were classified as low-grade or high-grade adenoma,cancer,SSA,or SSA with cytological dysplasia,and the prevalence of each type of polyp was investigated.Predictors of adenoma and SSA detection were examined using logistic generalized estimating equation models.The association between ADR and SSADR for each gastroenterologist was investigated by calculating a correlation coefficient weighted by the number of each gastroenterologist’s examination.RESULTS A total of 3691 colonoscopies performed by 35 gastroenterologists were assessed.Overall,978(26.5%)lowand 84(2.2%)high-grade adenomas,81(2.2%)cancers,66(1.8%)SSAs,and 2(0.1%)SSAs with cytological dysplasia were detected.Overall ADR was 29.5%(men 33.2%,women 23.8%)and overall SSADR was 1.8%(men 1.7%,women 2.1%).In addition,672 low-grade adenomas(68.8%of all the detected lowgrade adenomas),58(69.9%)high-grade adenomas,29(34.5%)cancers,52(78.8%)SSAs,and 2(100%)SSAs with cytological dysplasia were found in the proximal colon.Adenoma detection was the only significant predictor of SSA detection(adjusted OR:2.53,95%CI:1.53-4.20;P<0.001).The correlation coefficient between ADR and SSADR weighted by the number of each gastroenterologist’s examinations was 0.606(P<0.001).CONCLUSION Our results demonstrated that ADR is correlated to SSADR.In addition,patients with adenomas had a higher prevalence of SSAs than those without adenomas. 展开更多
关键词 Sessile serrated ADENOMA Sessile serrated ADENOMA DETECTION RATE ADENOMA DETECTION RATE COLONOSCOPY INTERVAL colorectal cancer
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Decision-Making Process in Japanese Board Room. Audit & Supervisory Board as a Source of Information to Outside Board Members: A Systematic Review 预览
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作者 Maria Vasileva Ilieva Jin-ichiro Yamada 《现代会计与审计:英文版》 2018年第1期17-34,共18页
关键词 会计学 审计工作 财务管理 审计学
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Integrated in-process chatter monitoring and automatic suppression with adaptive pitch control in parallel turning
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作者 Shuntaro Yamato Yuki Yamada +3 位作者 Kenichi Nakanishi Norikazu Suzuki Hayato Yoshioka Yasuhiro Kakinuma 《先进制造进展:英文版》 CAS CSCD 2018年第3期291-300,共10页
Responses of the Adult Rat Glucose Metabolism to Early Life Feeding, Caloric Restriction and Refeeding 预览
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作者 Nayra T. D. Branquinho Monica S. M. Loiola +7 位作者 Leticia D. Crepaldi Lais A. Yamada Silvia C. S. F. Azevedo Camila Bataglini Marcia N. Brito Vilma A. F. de Godoi Maria Montserrat D. Pedrosa Maria Raquel M. Natali 《药剂与药理学:英文版》 2018年第4期370-379,共10页
关键词 新陈代谢 葡萄糖 老鼠 热量 成年 生活 胰岛素抵抗 VIVO
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Clinical efficacy of a combination of Percoll continuous density gradient and swim-up techniques for semen processing in HIV-1 serodiscordant couples
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作者 Osamu Inoue Naoaki Kuji +7 位作者 Hiroe Ito Mitsutoshi Yamada Toshio Hamatani Aimi Oyadomari Shingo Kato Hideji Hanabusa Keiichi Isaka Mamoru Tanaka 《亚洲男性学杂志:英文版》 SCIE CAS CSCD 2017年第2期208-213,共6页
为了评估从 HIV-1 的精液为人的免疫不全病毒类型 1 的移动( HIV-1 )包括 Percoll 连续密度坡度和修改游泳起来技术的联合的一个过程的临床的功效,感染了男性, 129 的一个总数结合 HIV-1 积极男搭挡和 HIV-1 在在2002年1月和2012年4... 为了评估从 HIV-1 的精液为人的免疫不全病毒类型 1 的移动( HIV-1 )包括 Percoll 连续密度坡度和修改游泳起来技术的联合的一个过程的临床的功效,感染了男性, 129 的一个总数结合 HIV-1 积极男搭挡和 HIV-1 在在2002年1月和2012年4月之间的 Keio 大学医院被对待的否定女搭挡( serodiscordant 夫妇)被检查。从 129 HIV-1 的 183 精液的一个总数感染了男性被处理。在游泳起来以后,我们成功地在恢复收集了能动精子在 normozoospermia (126/126 精液) 的情况下象 100.0% 一样高的率, oligozoospermia (6/6 ) ,和 asthenozoospermia (36/36 ) 。oligoasthenozoospermia 的恢复率是 86.7%(13/15 ) 。在处理精液,仅仅四精液(4/181:2.2%) 在感染的男性的血显示出与那些一致的病毒的核苷酸序列。在使用这些精子以后,女病人的水平感染和新生儿的没有垂直感染都没被观察。而且,没有明显的不利效果在后代被观察。这个协议允许我们收集在高度的否定能动精子评估的 HIV-1,甚至在男因素盒子中。我们断定我们的协议为减少的 HIV-1 感染并且为产出一个健康孩子是临床上有效的。 展开更多
采用高强度钢减轻连杆质量 预览
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作者 T.Kaiho S.Yamada +4 位作者 T.Tsuruda M.Kubota S.Teramoto 高英英 朱炳全 《国外内燃机》 2017年第2期40-43,共4页
为了提高汽车的燃油经济性,需要进一步减轻零部件的质量。减轻运动件(例如连杆)的质量对于降低相邻运动件的质量尤为重要。采用高强度钢能减小连杆杆身横截面,从而减轻连杆的质量。然而,传统高强度钢的机加工性能很差。因此,开发了1种... 为了提高汽车的燃油经济性,需要进一步减轻零部件的质量。减轻运动件(例如连杆)的质量对于降低相邻运动件的质量尤为重要。采用高强度钢能减小连杆杆身横截面,从而减轻连杆的质量。然而,传统高强度钢的机加工性能很差。因此,开发了1种连杆用的新高强度钢,它以中碳微合金钢为基础,并添加了能够提高屈强比的钒元素。与传统钢相比,新开发的高强度钢的强度提高了10%。采用新高强度钢制造的连杆其质量能减轻8%。这种连杆已从2013年开始进行批量生产,应用于车用发动机。 展开更多
关键词 高强度钢 连杆 轻量化 机械特性
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First successful perinatal management of pregnancy after ABO-incompatible liver transplantation 预览
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作者 Hisanobu Higashi Hideaki Obara +12 位作者 Kei Miyakoshi Masahiro Shinoda Minoru Kitago Naoki Shimojima Yuta Abe Taizo Hibi Hiroshi Yagi Kentaro Matsubara Yohei Yamada Osamu Itano Ken Hoshino Tatsuo Kuroda Yuko Kitagawa 《世界胃肠病学杂志:英文版》 SCIE CAS 2017年第3期547-550,共4页
Many papers have reported on pregnancy and delivery after liver transplantation, but there have been no reports on pregnancy after ABO-incompatible liver transplantation. This paper reports the first successful pregna... Many papers have reported on pregnancy and delivery after liver transplantation, but there have been no reports on pregnancy after ABO-incompatible liver transplantation. This paper reports the first successful pregnancy and delivery of a newborn after ABOincompatible liver transplantation for fulminant hepatic failure. The patient was a 39-year-old female. She had an ABO-incompatible liver transplantation, donated from her husband, due to subacute fulminant hepatitis of unknown etiology. She was taking tacrolimus, methylprednisolone, and mizoribine orally for the maintenance of immunosuppression at the time of discharge. She was discharged uneventfully on postoperative day 38 without any rejection episodes. At 1 year and 6 mo after transplantation, she indicated a wish to become pregnant. Therefore, treatment with mycophenolate mofetil was interrupted at that time. After two miscarriages, she finally became pregnant and delivered transvaginally 3 years after the transplantation. All of the pregnancies were conceived naturally. The newborn was female with a birth weight of 3146 g;the Apgar scores were 9 and 10. Delivery was performed smoothly, and the newborn exhibited no malformations. The mother and the newborn were discharged uneventfully. We suggest that pregnancy is possible for recipients after ABO-incompatible liver transplantation. 展开更多
关键词 PREGNANCY Liver transplantation Delivery FULMINANT HEPATIC failure ABO-INCOMPATIBLE Living DONOR
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Rat Hepatocyte Glucose Metabolism Is Affected by Caloric Restriction but not by Litter Size Reduction 预览
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作者 Nayra Thais Delatorre Branquinho Gabriel Henrique de Paula Cruz +5 位作者 Arielle da Cunha Silvéio Leticia Diniz repaldi Lais Akemi Yamada Isabela Ramos Mariano Vilma Aparecida Ferreira de Godoi Maria ontserrat Diaz Pedrosa 《药剂与药理学:英文版》 2017年第7期408-415,共8页
关键词 葡萄糖代谢 大鼠肝脏 热量限制 肝细胞 产仔数 哺乳期饲养 胰岛素抵抗 相关疾病
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