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色阻堆叠在阵列基板上形成液晶屏隔垫物的研究 预览
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作者 张翼鹤 曹武 +4 位作者 李轩 林永伦 邱钟毅 Ray 周航 《液晶与显示》 CAS CSCD 北大核心 2019年第2期130-135,共6页
报道了一种新型液晶显示屏间隙支撑隔垫物的关键技术,可以替换传统的半透/灰阶曝光工艺,仅使用一张普通的全透光罩即可实现不同的支撑高度需求,并且达到遮光的效果,大幅节约了制备成本,可用于曲面或柔性显示面板。其中,主要隔垫物由两... 报道了一种新型液晶显示屏间隙支撑隔垫物的关键技术,可以替换传统的半透/灰阶曝光工艺,仅使用一张普通的全透光罩即可实现不同的支撑高度需求,并且达到遮光的效果,大幅节约了制备成本,可用于曲面或柔性显示面板。其中,主要隔垫物由两层色阻材料堆叠衬垫并覆盖平坦化层及黑色的光阻材料形成高度,辅助隔垫物由一层色阻衬垫并覆盖平坦化层及黑色的光阻材料形成高度,主/辅隔垫物的各自高度及它们之间的段差可以通过改变衬垫色阻的尺寸及平坦化层厚度进行调节。这种调节方式可以使主隔垫物高度的调节范围达0.6μm,辅助隔垫物高度的调节范围为0.5μm,它们之间的段差可以在0.2~1.3μm之间调节,理想段差位于此区间内。基于上述技术制备的液晶显示屏具有良好的显示效果,可用于高世代大尺寸液晶显示面板的生产。 展开更多
关键词 间隙隔垫物 色阻堆叠 高度调节
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Optimization and modeling of coagulation-flocculation to remove algae and organic matter from surface water by response surface methodology
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作者 Ziming Zhao Wenjun Sun +3 位作者 Madhumita BRay Ajay K Ray Tianyin Huang Jiabin Chen 《环境科学与工程前沿(英文)》 SCIE EI CAS CSCD 2019年第5期115-127,共13页
Seasonal algal blooms of Lake Yangcheng highlight the necessity to develop an effective and optimal water treatment process to enhance the removal of algae and dissolved organic matter (DOM). In the present study, the... Seasonal algal blooms of Lake Yangcheng highlight the necessity to develop an effective and optimal water treatment process to enhance the removal of algae and dissolved organic matter (DOM). In the present study, the coagulation performance for the removal of algae, turbidity, dissolved organic carbon (DOC) and ultraviolet absorbance at 254 nm (UV254) was investigated systematically by central composite design (CCD) using response surface methodology (RSM). The regression models were developed to illustrate the relationships between coagulation performance and experimental variables. Analysis of variance (ANOVA) was performed to test the significance of the response surface models. It can be concluded that the major mechanisms of coagulation to remove algae and DOM were charge neutralization and sweep flocculation at a pH range of 4.66–6.34. The optimal coagulation conditions with coagulant dosage of 7.57 mg Al/L, pH of 5.42 and initial algal cell density of 3.83 × 106 cell/mL led to removal of 96.76%, 97.64%, 40.23% and 30.12% in term of cell density, turbidity, DOC and UV254 absorbance, respectively, which were in good agreement with the validation experimental results. A comparison between the modeling results derived through both ANOVA and artificial neural networks (ANN) based on experimental data showed a high correlation coefficient, which indicated that the models were significant and fitted well with experimental results. The results proposed a valuable reference for the treatment of algae-laden surface water in practical application by the optimal coagulation-flocculation process. 展开更多
关键词 ALGAE COAGULATION-FLOCCULATION Response surface methodology Artificial neural networks
Curcuma angustifolia ameliorates carbon tetrachloride-induced hepatotoxicity in HepG2 cells and Swiss albino rats
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作者 Sudipta Jena Asit Ray +5 位作者 Diptirani Rath Ambika Sahoo Subhashree Singh Noohi Nasim Durga Madhab Kar Sanghamitra Nayak 《亚太热带医药杂志:英文版》 SCIE CAS 2019年第9期416-424,共9页
Objective:To determine the antioxidant and hepatoprotective potential of methanol extract of rhizome of Curcuma angustifolia(MECA)against carbon tetrachloride(CCl4)-induced hepatic damage in vitro and in vivo.Methods:... Objective:To determine the antioxidant and hepatoprotective potential of methanol extract of rhizome of Curcuma angustifolia(MECA)against carbon tetrachloride(CCl4)-induced hepatic damage in vitro and in vivo.Methods:DPPH,ABTS and reducing power assays were performed to estimate the antioxidant effect of MECA.In vitro cytotoxicity of MECA against HepG2 cells was evaluated,whereas serum biochemical parameters and levels of antioxidative enzymes were measured in vivo and in vitro.Additionally,histopathological studies were estimated in order to investigate the hepatoprotective efficacy of MECA.Furthermore,GC-MS analysis of the extract was performed to identify the chemical components.Results:MECA exhibited strong antioxidant activity and attenuated CCl4-induced decrease in the viability of HepG2 cells.Additionally,MECA significantly restored the ALT,AST,ALP,TP and albumin level in comparison with the CCl4 group.After pre-treatment with MECA,effects of SOD,CAT and GSH were increased as well as lipid peroxidation amount decreased on CCl4-induced hepatotoxicity in in vitro and in vivo model.Furthermore,histopathological observation confirmed that MECA reduced liver injury induced by CCl4 in rats.GC-MS analysis confirmed the presence of bioactive constituents such as α-tocopherol(12.27%),phytol(7.61%),squalene(3.71%),β-sitosterol(2.19%),eugenol(2.59%),curcumenol(1.20%),β-elemene(1.00%)and eucalyptol(0.89%).Conclusions:MECA contains antioxidant and hepatoprotective constituents such asα-tocopherol,phytol,squalene and eugenol and exerts hepatoprotective effect both in vitro and in vivo. 展开更多
关键词 CURCUMA angustifolia HEPATOPROTECTIVE ACTIVITY Carbon TETRACHLORIDE Antioxidant ACTIVITY HepG2 cells
基于DArT-Seq SNP的高密度遗传图谱的构建及野生型和栽培型西瓜杂交遗传群体偏分离基因组区域的鉴定 预览
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作者 任润生 羊杏平(编译) +6 位作者 Rumiana Ray 李苹芳 徐锦华 张曼 刘广 姚协丰 Andrzej Kilian 《中国瓜菜》 CAS 北大核心 2019年第8期172-173,共2页
目的与意义:西瓜[Citrullus lanatus (Thunb.) Matsum.et Nakai]是重要的蔬菜作物,在全世界范围内都广泛种植.构建高密度的西瓜遗传图谱和不断利用新开发的标记构建饱和遗传图谱仍然是目前西瓜基因组学研究的重要内容之一.本项研究主要... 目的与意义:西瓜[Citrullus lanatus (Thunb.) Matsum.et Nakai]是重要的蔬菜作物,在全世界范围内都广泛种植.构建高密度的西瓜遗传图谱和不断利用新开发的标记构建饱和遗传图谱仍然是目前西瓜基因组学研究的重要内容之一.本项研究主要以西瓜自交系‘K3’和野生西瓜种‘PI189225’为亲本构建F2分离群体,利用以DArTseq为基础的SNP标记构建西瓜高密度遗传连锁图谱. 展开更多
关键词 SNP标记 遗传图谱 基因组学 西瓜种 高密度 野生型 遗传群体 偏分离
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基于DArTSeq的SNP标记的西瓜核心种质遗传多样性和群体结构分析 预览
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作者 任润生 羊杏平(编译) +6 位作者 Ray 徐锦华 李苹芳 张曼 刘广 姚协丰 Andrzej Kilian 《中国瓜菜》 CAS 北大核心 2019年第8期174-175,共2页
目的与意义:亲本材料是进行育种工作的基础,遗传基础狭窄导致难以培育出突破性品种,因此亟需加强遗传资源的引进及其农艺性状特征和遗传基础的了解与掌握,对现有优良西瓜品种和育种亲本材料进行遗传多样性研究,可有效减少相似遗传背景... 目的与意义:亲本材料是进行育种工作的基础,遗传基础狭窄导致难以培育出突破性品种,因此亟需加强遗传资源的引进及其农艺性状特征和遗传基础的了解与掌握,对现有优良西瓜品种和育种亲本材料进行遗传多样性研究,可有效减少相似遗传背景的组合,减少育种的工作量。同时,随着分子生物学技术的发展,分子标记种类及检测手段日趋完善,利用分子标记技术对植物进行聚类分析,可以快速了解植物的遗传多样性、亲缘关系和品种鉴定等。本研究对37份核心西瓜种质进行遗传多样性分析,确定这些西瓜核心种质材料间的遗传背景差异,为后期育种工作中的亲本组配、等位基因发掘和标记辅助选择等提供参考。 展开更多
关键词 SNP标记 遗传图谱 基因组学 西瓜种 高密度 野生型 遗传群体 偏分离
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Primary implantation of non-valved glaucoma-drainage-device in sulcus in iridocorneal endothelial syndrome
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作者 Vanita Pathak Ray Divya P Rao Isha Gulati 《国际眼科杂志:英文版》 SCIE CAS 2019年第11期1809-1811,共3页
Dear Editor,I ridocorneal endothelial syndrome(ICE)is a rare,usually unilateral,acquired condition,hypothesized to be secondary to a viral etiology[1].It affects females more often than males and comprises of three di... Dear Editor,I ridocorneal endothelial syndrome(ICE)is a rare,usually unilateral,acquired condition,hypothesized to be secondary to a viral etiology[1].It affects females more often than males and comprises of three distinct clinical types related to endothelial proliferation and its structural abnormalities.Proliferation of endothelium over the iridocorneal angle leads to progressive secondary angle closure and that over the iris leads to typical changes of polycoria and atrophy.Three clinical entities included in the syndrome are Chandlers(predominant corneal involvement),progressive iris atrophy(predominant iris involvement with polycoria and‘holes’)and Cogan Reese(iris nodules with loss of stromal features).No matter what the clinical type,it is a progressive condition and controlling intraocular pressure(IOP)and maintaining corneal clarity in the long term is usually a challenge. 展开更多
关键词 CORNEAL INVOLVEMENT predominant
New Optical Soliton Solutions of Nolinear Evolution Equation Describing Nonlinear Dispersion
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作者 Saud Owyed M.A.Abdou +1 位作者 Abdel-Haleem Abdel-Aty S.Saha Ray 《理论物理通讯:英文版》 CSCD 2019年第9期1063-1068,共6页
In this work, we examine two algorithm schemes, namely, Kudryashov expansion and Auxiliary equation method for obtaining new optical soliton solutions of the discrete electrical lattice models in nonlinear scheme(Sale... In this work, we examine two algorithm schemes, namely, Kudryashov expansion and Auxiliary equation method for obtaining new optical soliton solutions of the discrete electrical lattice models in nonlinear scheme(Salerno equation). Our solutions obtained here are include the hyperbolic, rational, and trigonometric functions. Our two used methods are proved to be effective and powerful methods in obtaining the exact solutions of nonlinear evolution equations(NLEEs). 展开更多
关键词 discrete electrical LATTICE generalized Kudryashov expansion METHOD AUXILIARY equation METHOD EXACT SOLUTIONS
商业利益、透明度与独立性:征稿帮助推动从商业利益到独立性的发展
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作者 Ray Moynihan Helen Macdonald +3 位作者 Carl Heneghan Lisa Bero Fiona Godlee 罗丹(译) 《英国医学杂志中文版》 2019年第8期433-435,共3页
十年前,针对医学研究、教育和实践中的利益冲突问题,美国医学研究所(Institute of Medicine, IOM)颁布了一份具有划时代意义的报告。针对临床医生、研究人员和企业合作研发新产品的行为,这份报告强调了他们对健康事业进步带来的推动作用... 十年前,针对医学研究、教育和实践中的利益冲突问题,美国医学研究所(Institute of Medicine, IOM)颁布了一份具有划时代意义的报告。针对临床医生、研究人员和企业合作研发新产品的行为,这份报告强调了他们对健康事业进步带来的推动作用,但同时也提出担忧——广泛存在的商业关联会对专业性判断产生过度的影响。 展开更多
关键词 利益冲突 商业 透明度 医学研究所 临床医生 研究人员 健康事业
Evaluation of a locked nucleic acid form of antisense oligo targeting HIF-1α in advanced hepatocellular carcinoma 预览
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作者 Jennifer Wu Merly Contratto +5 位作者 Krishna P Shanbhogue Gulam A Manji Bert H O’Neil Anne Noonan Robert Tudor Ray Lee 《世界临床肿瘤学杂志(英文版)》 2019年第3期149-160,共12页
BACKGROUND Hypoxia-inducible factor 1α(HIF-1α) is a gene that regulates tumor survival,neovascularization and invasion. Overexpression of HIF-1α correlates with poor prognosis in hepatocellular carcinoma(HCC). RO70... BACKGROUND Hypoxia-inducible factor 1α(HIF-1α) is a gene that regulates tumor survival,neovascularization and invasion. Overexpression of HIF-1α correlates with poor prognosis in hepatocellular carcinoma(HCC). RO7070179 is a HIF-1α inhibitor that decreases HIF-1α mRNA and its downstream targets, it could be a potential treatment in HCC.AIM To evaluate safety and preliminary activity of RO7070179 in patients with previously treated HCC, with focus on a patient with prolonged response to RO7070179.METHODS In the preclinical study of RO7070179 in a HCC xenograft model, the mice wereseparated into 4 groups with each group received doses of 0, 3, 10 and 30 mg/kg for total 10 doses. HCC patients who failed at least one line of systemic treatment,received RO7070179 as a weekly infusion, each cycle is 6 wk. We evaluated the safety and HIF-1α mRNA levels of RO7070179.RESULTS Preclinical evaluation of RO7070179 in orthotopic HCC xenograft model showed no significant differences in HCC tumor weight between the 3 and 10 mg/kg groups. However, dose of 10 mg/kg of RO7070179, has shown 76% reduction of the amount of HIF-1α mRNA in HCC tissue. In the phase 1 b study of RO7070179 in previously treated HCC patients, 8 out of 9 were evaluable: 1 achieved PR and1 SD. The patient with PR responded after 2 cycles treatments, which has been maintained for 12 cycles. This patient also showed reduction in perfusion of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) after 1 cycle of treatment. After 1 cycle of treatment, both patients with PR and SD showed decrease in HIF-1α mRNA at the root of biopsies(each biopsy was divided into 2 specimens, the tip and the root).CONCLUSION RO7070179 can reduce HIF-1α mRNA level in HCC patients with SD or PR. It is well tolerated at 10 mg/kg, with transaminitis as the dose of increased toxicity.This study indicates that RO7070179 might benefit HCC patients, and an early signal for clinical benefit can potentially be predicted through changes in either m RNA level or DCE-MRI withi 展开更多
关键词 HEPATOCELLULAR carcinoma Hypoxia-inducible factor RO7070179 Superresponder Dynamic contrast-enhanced-magnetic RESONANCE imaging
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Higher-order approximate solutions of fractional stochastic point kinetics equations in nuclear reactor dynamics 预览
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作者 S. Singh S. Saha Ray 《核技术:英文版》 SCIE CAS CSCD 2019年第3期114-126,共13页
Stochastic point kinetics equations (SPKEs) are a system of Ito stochastic differential equations whose solution has been obtained by higher-order approximation. In this study, a fractional model of SPKEs has been ana... Stochastic point kinetics equations (SPKEs) are a system of Ito stochastic differential equations whose solution has been obtained by higher-order approximation. In this study, a fractional model of SPKEs has been analyzed. The efficiency of the proposed higher-order approximation scheme has been discussed in the results section. The solutions of SPKEs in the presence of Newtonian temperature feedback have also been provided to further discuss the physical behavior of the fractional model. 展开更多
关键词 FRACTIONAL STOCHASTIC POINT reactor kinetics equations FRACTIONAL CALCULUS HIGHER-ORDER approximation Caputo derivative NEUTRON population
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宁愿吃生活的苦,也不愿吃学习的苦? 预览
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作者 Ray 先森 《当代职校生》 2018年第9期30-31,共2页
中职阶段的实习,有一部分学生会去到流水线工厂。每天站在流水线前,干着相同的工作,从早8点到晚8点。但观察身边的工作人员,有可能会发现同龄人,当问到“为什么在本该上学的年龄出来打工”,除去一部分人是因为家境贫寒,出于无奈... 中职阶段的实习,有一部分学生会去到流水线工厂。每天站在流水线前,干着相同的工作,从早8点到晚8点。但观察身边的工作人员,有可能会发现同龄人,当问到“为什么在本该上学的年龄出来打工”,除去一部分人是因为家境贫寒,出于无奈需要贴补家用,大多数人的回答是:“上学太痛苦,不如打工赚钱来得容易。”这令人感到疑惑:“为什么大多数人宁愿吃生活的苦,也不愿吃学习的苦?” 展开更多
关键词 生活 学习 工作人员 流水线 学生会 同龄人 打工 实习
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Geochemical cycling during subduction initiation:Evidence from serpentinized mantle wedge peridotite in the south Andaman ophiolite suite 预览
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作者 Abhishek Saha M.Santosh +3 位作者 Sohini Ganguly C.Manikyamba Jyotisankar Ray Jagadish Dutta 《地学前缘:英文版》 CAS CSCD 2018年第6期1755-1775,共21页
The ophiolite suite from south Andaman Islands forms part of the Tethyan Ophiolite Belt and preserves the remnants of an ideal ophiolite sequence comprising a basal serpentinized and tectonised mantle peridotite follo... The ophiolite suite from south Andaman Islands forms part of the Tethyan Ophiolite Belt and preserves the remnants of an ideal ophiolite sequence comprising a basal serpentinized and tectonised mantle peridotite followed by ultramafic and mafic cumulate units,basaltic dykes and spilitic pillow basalts interlayered with arkosic wacke.Here,we present new major,trace,rare earth(REE)and platinum group(PGE)element data for serpentinized and metasomatized peridotites(dunites)exposed in south Andaman representing the tectonized mantle section of the ophiolite suite.Geochemical features of the studied rocks,marked by Al2O3/TiO2>23,LILE-LREE enrichment,HFSE depletion,and U-shaped chondrite-normalized REE patterns with(La/Sm)N>1 and(Gd/Yb)N<1,suggest contributions from boninitic mantle melts.These observations substantiate a subduction initiation process ensued by rapid slab roll-back with extension and seafloor spreading in an intraoceanic fore-arc regime.The boninitic composition of the serpentinized peridotites corroborate fluid and melt interaction with mantle manifested in terms of(i)hydration,metasomatism and serpentinization of depleted,MORB-type,sub-arc wedge mantle residual after repeated melt extraction;and(ii)refertilization of refractory mantle peridotite by boninitic melts derived at the initial stage of intraoceanic subduction.Serpentinized and metasomatized mantle dunites in this study record bothMOR and intraoceanic arc signatures collectively suggesting suprasubduction zone affinity.The elevated abundances of Pd(4.4e12.2 ppb)with high SPPGE/SIPGE(2e3)and Pd/Ir(2e5.5)ratios are in accordance with extensive melt-rock interaction through percolation of boninitic melts enriched in fluid-fluxed LILE-LREE into the depleted mantle after multiple episodes of melt extraction.The high Pd contents with relatively lower Ir concentrations of the samples are analogous to characteristic PGE signatures of boninitic magmas and might have resulted by the infiltration of boninitic melts into the depleted and residual mantle 展开更多
关键词 South Andaman OPHIOLITE MANTLE PERIDOTITE METASOMATISM Geochemical CYCLING SUBDUCTION initiation
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对于有症状重度主动脉瓣狭窄且外科手术风险低至中危的患者,是选择经导管还是外科主动脉瓣置换:临床实践指南
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作者 Per O Vandvik Catherine M Otto +13 位作者 Reed A Siemieniuk Rodrigo Bagur Gordon H Guyatt Lyubov Lytvyn Richard Whitlock Trond Vardal David Brieger Bert Aertgeerts Susanna Price Farid Foroutan Michael Shapiro Ray Mertz 郑骏楠 李伟栋 《英国医学杂志:中文版(BMJ)》 2018年第1期40-46,共7页
对于有症状重度主动脉瓣狭窄且外科心脏手术风险相对较低的患者,微创操作同直视手术相比孰优孰劣?结合最近的一项临床试验结果,专家组根据3个相关综述文献提出了如下几条建议。
关键词 症状 主动脉瓣狭窄 外科手术 患者
Emerging roles of the neural adaptor FE65 in neurite outgrowth 预览
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作者 Wen Li Wai Wa Ray Chan +1 位作者 Jacky Chi Ki Ngo Kwok-Fai Lau 《中国神经再生研究:英文版》 SCIE CAS CSCD 2018年第12期2085-2086,共2页
关键词 神经原 适配器 神经网络 身体 通讯 互连
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Elimination of ESD Events and Optimizing Waterjet Deflash Process for Reduction of Leakage Current Failures on QFN-mr Leadframe Devices 预览
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作者 Frederick Ray I.Gomez Tito T.Mangaoang Jr. 《电气工程:英文版》 2018年第4期238-243,共6页
关键词 高漏电流故障 故障分析 漏电保护 静电
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鸡源益生菌的体外和体内生物学模拟 预览
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作者 刘正旭(译) 王晶晶(校) +1 位作者 罗静如(制图表) Susim Mukul Ray 《国外畜牧学:猪与禽》 2018年第12期47-49,共3页
本文对鸡源益生菌进行了体外和体内的生物学模拟,分析了在两种情况下益生菌生长曲线4个阶段的不同特点,为实际生产条件下益生菌的有效应用提供参考。
关键词 鸡源益生菌 体外 体内 生物学模拟
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圆桌论坛二:互联与合作 预览
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作者 Satoru(Tomo)Yamadera Ray Yuen +2 位作者 Davin Cheung O’delle Burke Danny Missotten 《债券》 2018年第12期29-32,共4页
Satoru(Tomo)Yamadera:中国债券市场在近些年取得了令人瞩目的发展成绩,在市场规模上也已与日本债券市场旗鼓相当。目前,日本债券市场在全球(债券)指数所占份额大约是20%,倘若人民币债券被纳入全球指数中,我认为人民币债券也将占据相当... Satoru(Tomo)Yamadera:中国债券市场在近些年取得了令人瞩目的发展成绩,在市场规模上也已与日本债券市场旗鼓相当。目前,日本债券市场在全球(债券)指数所占份额大约是20%,倘若人民币债券被纳入全球指数中,我认为人民币债券也将占据相当的份额。就经济体量和债券市场规模而言,不少亚洲国家已经可以比肩部分欧洲国家,如何更好地使用这些国家的债券是当前值得我们思考的问题。 展开更多
关键词 债券市场 人民币债券 合作 论坛 市场规模 欧洲国家 亚洲国家 经济体
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Mid-infrared silicon photonic waveguides and devices [Invited]
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作者 YI Zou SWAPNAJIT CHAKRAVARTY +2 位作者 CHI-JUI CHUNG XIAOCHUAN XU RAY T. CHEN 《光子学研究:英文版》 2018年第4期254-276,共23页
关键词 光电子产业 硅电子 发展现状 通讯技术
Cancer and comorbidity:The role of leptin in breast cancer and associated pathologies 预览
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作者 Amitabha Ray 《世界临床病例杂志》 2018年第12期483-492,共10页
Obesity is an important risk factor for postmenopausal breast cancer and also a poor prognostic factor among cancer patients.Moreover,obesity is associated with a number of health disorders such as insulin resistance/... Obesity is an important risk factor for postmenopausal breast cancer and also a poor prognostic factor among cancer patients.Moreover,obesity is associated with a number of health disorders such as insulin resistance/type-2 diabetes mellitus,hypertension,and other cardiovascular diseases.Frequently,these health disorders exhibit as components/complications of the metabolic syndrome.Nevertheless,obesity-related diseases may coexist with postmenopausal breast cancer;and these comorbid conditions could be substantial.Therefore,it may be assumed that different diseases including breast cancer could originate from a common pathological background in excessive adipose tissue.Adipocyte-released hormone-like cytokine(or adipokine)leptin behaves differently in a normal healthy state and obesity.A growing body of evidence suggests an important role of leptin in our major obesity-related health issues such as insulin resistance,hypertension,and neoplasia.In this context,this review describes the relationships of the abovementioned pathologies with leptin. 展开更多
关键词 Hypertension Obesity POSTMENOPAUSAL BREAST CANCER COMORBIDITY Diabetes
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Design and Optimization of A Direct-Conversion Double-Balanced Mixer for RF Receiver Front-End 预览
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作者 Frederick Ray I. Gomez 《电工电子工程进展》 2018年第3期12-20,共9页
Differential implementation is becoming highly favoured in RFIC (radio frequency integrated circuit) design, notably its high immunity to common-mode noises, acceptable rejection of parasitic coupling, and increased d... Differential implementation is becoming highly favoured in RFIC (radio frequency integrated circuit) design, notably its high immunity to common-mode noises, acceptable rejection of parasitic coupling, and increased dynamic range. One specific RF front-end building block that is usually designed as a differential circuit is the mixer. This technical paper presents a study of a differential mixer, notably the double-balanced mixer implemented on a direct-conversion architecture in a standard 90nm CMOS (complementary metal-oxide semiconductor) process. Operating frequency is set at 5GHz, which is a typical frequency for RF (radio frequency) receiver. Impedance matching was essential to fully optimize the mixer design. The direct-conversion double-balance mixer design eventually achieved conversion gain of 11.463dB and noise figure of 16.529dB, comparable to mixer designs from past research and studies. 展开更多
关键词 Double-Balanced MIXER Direct CONVERSION CONVERSION Gain Noise FIGURE RF FRONT-END
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