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肝脏转运体表达和功能的变化对肝疾病的影响 认领 被引量:2
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作者 王鹤鹏 孙鹏远 刘克辛 《世界华人消化杂志》 CAS 2017年第16期1427-1437,共11页
转运体是药物吸收、分布、代谢和排泄的重要决定因素,在肝脏表达尤为广泛.肝脏转运体可以摄取大多数内源性物质、营养物质和外源性物质进入肝脏,在肝脏内经过一系列的代谢转化,最终将其外排入胆汁并由胆汁排到肝外.越来越多的证据表明... 转运体是药物吸收、分布、代谢和排泄的重要决定因素,在肝脏表达尤为广泛.肝脏转运体可以摄取大多数内源性物质、营养物质和外源性物质进入肝脏,在肝脏内经过一系列的代谢转化,最终将其外排入胆汁并由胆汁排到肝外.越来越多的证据表明肝脏疾病状态下转运体的表达和功能会发生改变,影响药物在体内的处置过程,进而增加药物相互作用的可能性,同时加大了疾病药物治疗的难度.本文从肝脏摄取型和外排型转运体两方面出发,针对肝脏转运体表达和功能的变化对肝疾病的影响作一综述. 展开更多
关键词 转运体 表达变化 功能变化 肝疾病
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Establishment of in vitro culture of Populus euphratica Olivier 认领
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作者 Zhao Peng Dong Zhan-yuan +2 位作者 Sun Hong-bin Zhao Ju-ying Wang Hua-fang 《中国林学:英文版》 CAS 2006年第4期 10-14,共5页
<正>The purpose of our study was to establish a regeneration system for micropropagation of Populus euphratica Olivier. On the basis of an analysis of plant leaf mineral nutrients, a special medium was proposed,... <正>The purpose of our study was to establish a regeneration system for micropropagation of Populus euphratica Olivier. On the basis of an analysis of plant leaf mineral nutrients, a special medium was proposed, called MP2. In optimizing media for in vitro plant cultures including MS, B5 and MP2 media we employed hormones, auxin IAA, cytokine benzyladenine (BAP) and gibberellic acid (GA) in our factorial experiments on media. Adventitious shoots were derived from cuttings of adult plants taken from Xingjiang, west China, on selected media with MP2+0.5 mg·L-1 BA+ 0.1 mg·L-1 NAA. The shoots were elongated on a medium with 0.25 mg·L-1 BAP, 0.1 mg·L-1 NAA and 2 mg·L-1 GA and were then rooted on a medium with 0.2-0.5 mg·L-1 IBA. All the media were incorporated with 30 g·L-1 sucrose and an adjusted pH at 6.3. 展开更多
关键词 杨树 植物激素 体外培养 微细增殖
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