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2005~2017年扬州市成人艾滋病患者抗病毒治疗生存分析 被引量:1

Analysis on survival of antiviral therapy among adult AIDS patients,Yangzhou city,2005-2017
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摘要 目的了解接受艾滋病高效联合抗反转录病毒治疗患者基本特征和治疗生存时间,分析影响其治疗生存时间的主要危险因素。方法收集整理国家艾滋病综合防治信息系统中扬州市2005~2017年相关资料,回顾性调查治疗病例的生存时间,并应用SPSS 19.0软件作数据分析。结果接受抗病毒治疗患者1 166例,因艾滋病相关死亡98例,治疗总病死率为2.50/100人年(98/3 916.91人年)。治疗后第0.5、1.0、2.0、3.0、4.0、5.0年生存率分别为98.20%、97.17%、94.51%、93.31%、92.71%、92.20%。65.31%(64/98)治疗病例的死亡发生在治疗后两年以内;职业、感染途径、婚姻状态及基线CD4+T细胞值等因素对抗病毒治疗患者生存时间有影响(P <0.01、<0.05)。结论扬州市成人艾滋病抗病毒治疗生存率高于全国平均水平。 Objective To understand the basic characteristics and survival time of HIV-infected/AIDS patients(HIV/AIDS)who received highly active anti-retroviral therapy(HAART)during 2005-2017 in Yangzhou city,and to analyze the main risk factors which affecting the survival time. Methods Data was collected from the National AIDS Comprehensive Data Information System during 2005-2017.Survival time of adult HIV-infected/AIDS patients were retrospectively investigated,and analyzed by SPSS 19.0 software. Results There were 98 death cases among 1 166 HIV-infected/AIDS cases received HAART,with the mortality of 2.50%/person-year(98/3 916.91person-year).The survival rate was 98.20%,97.17%,94.51%,93.31%,92.71%,92.20% respectively after 0.5,1.0,2.0,3.0,4.0,5.0 years of HAART.There was 65.31%(64/98) of the patients died within 2 years after HAART.Patients’ survival time was affected by occupations,routes of infection,marriage status,and baseline CD4+T cell value(P <0.01,P <0.05). Conclusion The survival rate of adult HIV/AIDS patients who received HAART in Yangzhou city is higher than the national average level.
作者 韦正亚 曹颖 WEI Zheng-ya;CAO Ying(Yangzhou City Center for Disease Control and Prevention,Yangzhou,Jiangsu,225001,China)
出处 《预防医学论坛》 2018年第11期864-865,868共3页 Preventive Medicine Tribune
关键词 获得性免疫缺陷综合征 高效抗反转录病毒治疗 生存分析 Acquired immunodeficiency syndrome Highly active anti-retroviral therapy Survival analysis
作者简介 韦正亚(1978~),男,硕士,主管医师,研究方向:艾滋病防治
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