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增材制造技术在骨缺损修复治疗中的应用 预览

Application of additive manufacturing technology in bone defects
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摘要 背景:增材制造技术凭借其能快速精准制备出假体的优点,在骨缺损治疗方面应用广泛。目的:对增材制造技术在骨缺损方面的临床应用现状做一综述。方法:由第一作者检索PubMed、CNKI、万方数据库2000至2018年收录的有关增材制造与骨缺损的文献,中文检索词为'骨缺损,增材制造,3D打印技术,骨肿瘤',英文检索词为'Bone defect,Additive Manufacturing(AM),3D Printing,Bone tumour'。结果与结论:①增材制造技术能结合现代影像技术,快速进行体外的假体三维重建;②治疗骨缺损时不仅能在术前构建骨缺损模型进行模拟手术,熟悉和对比手术方式,有效减少实际手术时间;还能快速精准的制备出形状各异的植入物,明显提高手术成功率;③增材制造技术展现出在骨缺损临床应用方面的优势。 BACKGROUND: Additive material manufacturing technology is widely used in the treatment of bone defects because of its advantages of rapid and accurate preparation of prostheses.OBJECTIVE: To review the current situation of material addition technology applied in bone defects.METHODS: The first author searched the articles related to additive manufacturing and bone defect repair in PubMed, CNKI, and WanFang databases published from 2000 to 2018. The keywords were 'bone defect,additive manufacturing(AM), 3D printing, bone tumour' in Chinese and English, respectively.RESULTS AND CONCLUSION:(1) The additive manufacturing technology can rapidly reconstruct the three-dimensional prosthesis in vitro with modern imaging technology.(2) In the treatment of bone defects, we cannot only establish the model of bone defects before operation to simulate the operation, familiarize and compare the operation methods, and effectively reduce the operation time, but also can quickly and accurately prepare different varieties of implants, significantly improving the success rate of surgery.(3) Additive manufacturing technology shows good prospects in the clinical application of bone defects.
作者 方旭 董军峰 Fang Xu;Dong Junfeng(Department of Spinal Surgery,the First Clinical Medical College of Three Gorges University(Yichang Central People’s Hospital),Yichang 443003,Hubei Province,China;Institute for Spinal Medicine and Trauma,Three Gorges University,Yichang 443003,Hubei Province,China)
出处 《中国组织工程研究》 CAS 北大核心 2019年第18期2915-2920,共6页 Journal of Clinical Rehabilitative Tissue Engineering Research
基金 国家自然科学基金(青年基金项目)(31600779) 宜昌市医疗卫生科研项目(A18-301-30).
关键词 增材制造 骨缺损 骨修复 骨肿瘤 三维重建 模拟手术 快速精准制造 植入物 国家自然科学基金 additive manufacturing bone defects bone repair bone tumor three-dimensional reconstruction simulating surgery quick and accurate preparation implants the National Natural Science Foundation of China
作者简介 方旭,男,1994年生,湖北省荆州市人,三峡大学外科学在读硕士,主要从事脊柱外科、生物材料与骨组织工程研究;通讯作者:董军峰,博士,副主任医师,硕士生导师,三峡大学第一临床医学院(宜昌市中心人民医院)脊柱外科,湖北省宜昌市443003.
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