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早期食管癌血清肿瘤标志物的研究进展 认领

Advances in serum tumor markers of early esophageal cancer
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摘要 食管癌是消化系统恶性肿瘤,病死率居中国癌症第4位。食管癌患者确诊时多为中晚期,这是因为本病早期临床症状不典型,也无早期的特异性诊断方法。因此早期肿瘤筛查对本病诊断有关键作用。临床上应用最广泛的肿瘤筛查方法是血清肿瘤标志物检测,它具有快速、微创、简便、可动态观测的特性。血清肿瘤标志物有许多项,其中CA125、CYFRA21-1、CA19-9、CEA、SSC-Ag为目前临床研究的热点,因此本文就此5项标志物与早期食管癌相关性的研究进展进行简要综述。 Esophageal cancer is a malignant tumor of the digestive system,and its fatality rate ranks the fourth in China.Most patients with esophageal cancer are diagnosed in the middle and late stage,because the clinical symptoms of the disease are not typical in the early stage,and there is no early specific diagnostic method.Therefore,early tumor screening plays a key role in the diagnosis of the disease.The most widely used tumor screening method is serum tumor marker detection,which has the characteristics of rapid,minimally invasive,simple,and dynamic observation.There are many serum tumor markers,among which CA125,CYFRA21-1,CA19-9,CEA,and SSC-AG are the hot spots in clinical research at present.Therefore,this paper summarizes the research progress of correlation between the five markers and early esophageal cancer.
作者 黄丛改 汪少华 刘云 易红 杨志惠 Huang Conggai;Wang Shaohua;Liu Yun;Yi Hong;Yang Zhihui(Department of Pathology,The Affiliated Hospital of Southwest Medical University,Luzhou 646000,China)
出处 《国际医药卫生导报》 2020年第19期2846-2849,共4页 International Medicine and Health Guidance News
基金 四川省科技计划项目(2018JY0398)。
关键词 食管癌 早期诊断 血清 肿瘤标志物 Esophageal cancer Early diagnosis Serum Tumor marker
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