Objective To evaluate the potentially inappropriate medication(PIM)in senile dementia inpatients.Methods A total of 398 senile dementia and/or cognitive impairment inpatients(≥65 years)in the Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University from January 2018 to December 2019 were collected according to the systematic sampling method.The Beers criteria(2015)and Anticholinergic Cognitive Burden(ACB)scale were used to evaluate the PIM situation.The Logistic test was used to analyze the correlation between the two evaluation results,and the Kappa test was used to test the consistency of the two evaluation results.Results Among the 398 inpatients,the incidence of at least 1 kind of PIM was 119 cases(29.90%),78 cases(19.60%)had high-risk medications for cognitive impairment;the two criteria for evaluating the highest incidence of PIM were all antipsychotic drugs;the ACB scale evaluation of cardiovascular system drugs and respiratory system drugs also showed a slight risk of cognitive impairment.The risk factor analysis results showed that the increase in the number of hospitalization days,the number of diagnoses,and the number of medications all increased the incidence of PIM(P<0.05);the two criteria that evaluated the consistency of the incidence of this PIM was general(Kappa=0.634).Conclusion Both the Beers criteria and ACB scale have important value in evaluating the PIM risks of senile dementia inpatients.The combined application of the two may further increase the reasonable medication level of senile dementia patients.
senile dementia inpatients
Anticholinergic Cognitive Burden scale
potentially inappropriate medication
rational drug use