目的探讨产前抑郁与产后抑郁症的关系。方法选择银川市妇幼保健院与中卫市中医院2所医院的200名住院待产妇,采用抑郁自评量表(self rating depression scale,SDS)与爱丁堡产后抑郁量表(Edinburgh postnatal depression scale,EPDS)分别调查产前与产后抑郁状况。结果 200名产妇产前抑郁检出率为20.0%,产后3 d抑郁检出率为26.0%,产后42 d检出率为15.5%。有产前抑郁的产妇产后3 d(χ^2=9.381,P=0.002)、产后42 d(χ^2=11.923,P=0.001)抑郁检出率高于无产前抑郁者。Pearson相关分析显示,产前SDS得分与产后3 d的EPDS得分、与产后42 d的EPDS得分均呈正相关(均有P<0.05)。广义估计方程分析亦得出产前抑郁与产后3 d抑郁、产后42 d抑郁均呈正相关(均有P<0.05)。多因素Logistic回归分析模型显示产前抑郁是产后3 d抑郁(OR=2.678,95%CI:1.241~5.781,P=0.012)、产后42 d抑郁(OR=3.180,95%CI:1.303~7.763,P=0.011)的危险因素。结论产前抑郁与产后抑郁症呈正相关,产前抑郁增加了产后抑郁症的危险性。
Objective To explore the relationship between prenatal depression and postpartum depression. Methods Self rating depression scale(SDS) and Edinburgh postnatal depression scale(EPDS) was used to investigated the prenatal and postpartum depression status in 200 pregnant women from the Yinchuan maternal and child health hospital and the Zhongwei traditional chinese medicine hospital. Results The prevalence rate of prenatal depression in 200 women was 20.0%, the prevalence rate of 3 days postpartum depression was 26.0%, and the prevalence rate of 42 days postpartum depression was 15.5%. The prevalence rate of 3 days postpartum depression with prenatal depression in female were higher than that in female without prenatal depression(χ^2=9.381, P=0.002). So were female that 42 days postpartum depression with prenatal depression(χ^2 =11.923, P=0.001). The difference was statistically significant. Pearson correlation analysis showed that SDS score was positively correlated with EPDS score at 3 days postpartum and 42 days postpartum(all P < 0.05). Generalized estimating equation analysis also showed that prenatal depression was positively correlated with depression at 3 days postpartum and 42 days postpartum(all P < 0.05). Multivariate logistic regression analysis showed that prenatal depression was a risk factor for depression at 3 days postpartum(OR=2.678,95% CI:1.241-5.781, P=0.012) and 42 days postpartum depression(OR =3.180,95% CI:1.303-7.763, P=0.011). Conclusion Prenatal depression is positively associated with postpartum depression, and prenatal depression increases the risk of postpartum depression.
Chinese Journal of Disease Control & Prevention