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稳心颗粒联合酒石酸美托洛尔治疗冠心病合并心律失常临床 疗效及安全性分析 预览

Clinical Efficacy and Safety of Wenxin Granule Combined with Metoprolol Tartrate in Treatment of Patients with Coronary Heart Disease Associated by Arrhythmia
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摘要 目的探讨稳心颗粒联合酒石酸美托洛尔治疗冠心病合并心律失常的临床疗效及安全性。方法选取我院2018年2—10月收治的冠心病合并心律失常82例,根据治疗方案分为观察组和对照组各41例,对照组予以酒石酸美托洛尔片口服,观察组在此基础上给予稳心颗粒口服。观察2组临床疗效、心功能及心电图改善情况及不良反应发生率。结果观察组总有效率高于对照组,心功能指标及心电图改善情况优于对照组,不良反应发生率低于对照组(P<0.05,P<0.01)。结论稳心颗粒联合酒石酸美托洛尔治疗冠心病合并心律失常临床疗效更好,安全性更高。 Objective To investigate clinical efficacy and safety of Wenxin granule combined with Metoprolol Tartrate in treatment of patients with coronary heart disease associated by arrhythmia.Methods A total of 82 patients with coronary heart disease associated by arrhythmia admitted from February to October 2018 were divided into observation group(n=41)and control group(n=41)according to different treatments.Control group was given Metoprolol Tartrate orally,while observation group was supplemented with Wenxin granule orally on the basis of treatment for control group.Clinical efficacy,improved conditions of heart function and electrocardiogram and incidence rate of adverse reactions were observed in two groups.Results In observation group,the total effective rate was significantly higher,and improved conditions of heart function and electrocardiogram were significantly better,and incidence rate of adverse reactions was significantly lower than those in control group(P<0.05,P<0.01).Conclusion Wenxin granule combined with Metoprolol Tartrate in treatment of patients with coronary heart disease associated by arrhythmia may achieve good clinical efficacy with good safety.
作者 张媛媛 高行军 康启 赵运 ZHANG Yuan-yuan;GAO Xing-jun;KANG Qi;ZHAO Yun(Department of Pharmacy,the Second Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine,Xianyang,Shaanxi 712000,China;Department of Cardiology,the Second Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine,Xianyang,Shaanxi 712000,China)
出处 《解放军医药杂志》 CAS 2020年第1期89-92,共4页 Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
基金 陕西省卫生计生科研基金项目(2016D056)。
关键词 冠心病 心律失常 稳心颗粒 酒石酸美托洛尔 每搏输出量 心电描记术 Coronary disease Arrhythmias Wenxin granules Metoprolol tartrate Stroke volume Electrocardiography
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