With the development and utilization of drugs,the cases of drug-induced liver injury( DILI) have been gradually discovered during clinical treatment. By investigating clinical cases,researchers in different countries summarized the clinical classification and manifestations of DILI diagnosis,and found that many DILI patients belong to idiosyncratic type.However,the causes are widely various among individuals,and the clinical manifestations are also complex. And the method of diagnosis is an exclusive diagnosis,which still needs judgement by causal assessment. Therefore,it is still difficult to identify the specific cause of abnormal liver function after medication. By continuously collecting drug information on the risk of liver damage,and continuous discovery of new biomarkers in laboratory,it’ s expected to provide effective help for DILI differential diagnosis in the future.
Drug-induced liver injury