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氟哌噻吨美利曲辛片联合头痛宁胶囊治疗慢性偏头痛的临床效果 预览

Clinical study of flupentixol militacin tablets combined with headache capsule in the treatment of chronic migraine
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摘要 目的观察氟哌噻吨美利曲辛片联合头痛宁胶囊治疗慢性偏头痛的临床效果。方法选取慢性偏头痛患者98例,随机分为两组,每组49例。对照组予以头痛宁胶囊治疗,实验组在此基础上予以氟哌噻吨美利曲辛片治疗。两组均连续治疗4周,对比两组治疗疗效、不良反应发生率及治疗前后发作程度(发作时疼痛程度、发作次数、单次持续时间)、焦虑(HAMA)、抑郁(HAMD)情况。结果实验组总有效率较对照组高(P<0.05);与对照组比较,实验组治疗后发作次数及单次发作时间较对照组少,HAMA、HAMD评分及发作时疼痛程度评分较对照组低(P<0.05);两组不良反应发生率无差异(P>0.05)。结论对慢性偏头痛患者予以氟哌噻吨美利曲辛片、头痛宁胶囊联合治疗,可显著降低患者发作程度及负性情绪,进一步提高治疗效果,且安全性高。 Objective To explore the clinical effect of flupentixol militacin tablets combined with headache capsule in the treatment of chronic migraine.Methods A total of 98 patients with chronic migraine were enrolled and randomly divided into two groups,49 cases in each group.The control group was treated with headache capsules.The experimental group was treated with flupentixol melitracen tablets on the basis of the control group.Both groups were treated continuously for four weeks.The total effective rate,the incidence of adverse reactions,and the degree of attack before and after treatment(pain degree at the time of onset,number of episodes,single duration time),anxiety(HAMA),and depression(HAMD)were compared between the two groups.Results The total effective rate of the experimental group was higher than that of the control group(P<0.05).Compared with the control group,the number of episodes and single duration time in the experimental group were less than those in the control group;HAMA,HAMD score and pain degree at the time of onset were lower than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The flupentixol melitraceol tablets combined with headache capsule can significantly reduce the degree of episodes and negative emotions,further improve the treatment effect,which has high safety and worthy of promotion.
作者 任璐 REN Lu(Henan Provincial Staff Hospital,Zhengzhou 450000,Henan)
机构地区 河南省职工医院
出处 《菏泽医学专科学校学报》 2019年第3期28-30,共3页 Journal of Heze Medical College
关键词 慢性偏头痛 氟哌噻吨美利曲辛片 头痛宁胶囊 Chronic migraine Flupentixol militacin tablets Headache capsule
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