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热毒宁注射液联合甲强龙治疗小儿支原体肺炎的临床效果 预览

Clinical effect of Resin injection combined with methylprednisolone in the treatment of children with mycoplasmal pneumonia
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摘要 目的:分析热毒宁联合甲强龙治疗小儿支原体肺炎疗效及对血清炎症因子、病毒抗原转阴率的影响。方法:在本院2016年5月至2018年5月间收治的所有小儿支原体肺炎患儿中随机挑选70例患儿作为研究对象,采用单盲法将其分为研究组和对照组,每组中均纳入35例患儿。对照组患儿实施甲强龙治疗,研究组患儿实施热毒宁和甲强龙联合治疗方案。观察两组患儿血清炎症因子的变化,同时对比其治疗有效率和病毒抗原转阴率。结果:本次研究结果显示,和研究组相对比,对照组患儿的血清IL-2R、IL-6、TNF-α较高,而对比病毒抗原转阴率和治疗有效率,研究组分别为91.43%和97.14%,明显优于对照组的65.71%和80.00%,差异具有统计学意义(P<0.05)。结论:热毒宁联合甲强龙对于小儿支原体肺炎的治疗效果明显优于单一的药物治疗,能够降低患儿的炎症反应,同时病毒抗原转阴率较高,是一种安全有效的治疗方式。 Objective:To analyze the efficacy of Resin-Ning combined with Jiaqianglong in the treatment of children with mycoplasmal pneumonia and its effect on serum inflammatory factors and viral antigen conversion rate.Methods:70 children with pediatric mycoplasmal pneumonia admitted to our hospital from May 2016 to May 2018 were randomLy selected as experimental subjects.They were divided into experimental group and control group by single blind method.All of the 35 children were included.The control group was treated with methylprednisolone,and the experimental group was treated with the combination of Rexin and Jiaqianglong.The changes of serum inflammatory factors in the two groups were observed,and the therapeutic efficiency and viral antigen conversion rate were compared.Results:The results of this study showed that compared with the experimental group,the serum IL-2R,IL-6,and TNF-αwere higher in the control group,while the contrast ratio of the virus antigen and the effective rate of treatment were compared.91.43%and 97.14%were significantly better than the control group of 65.71%and 80.00%,the difference was statistically significant(P<0.05).Conclusion:Resin-Ning combined with methylprednisolone is better than single drug therapy in treating children with mycoplasmal pneumonia.It can reduce the inflammatory reaction of children and has a high rate of viral antigen conversion.It is a safe and effective treatment.
作者 杜林军 Du Linjun(Liaocheng Third People's Hospital,Liaocheng,Shandong 252000)
出处 《中外女性健康研究》 2019年第15期7-8,共2页 Women's Health Research
关键词 热毒宁 甲强龙 小儿支原体肺炎 血清炎症因子 病毒抗原转阴率 Resin Methylprednisolone Pediatric mycoplasma pneumonia Serum inflammatory factors Viral antigen conversion rate
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