期刊文献+

短时程脊髓电刺激治疗亚急性期带状疱疹性神经痛的短期疗效

Short-term spinal cord electrical stimulation for the treatment of patients with sub-acute herpetic neuralgia
收藏 分享 导出
摘要 目的观察短时程脊髓电刺激治疗亚急性期带状疱疹性神经痛的短期疗效。方法收集2016年1月至2018年6月贵州省人民医院疼痛科、神经内科收治的亚急性带状疱疹神经痛患者23例,年龄60~80岁,性别不限,行短时程脊髓电刺激治疗,将电极置入硬膜外腔,刺激脊髓后角感觉神经元及后柱传导束,治疗10~14d后拔出电极。评估治疗前后不同时点的VAS评分,采用睡眠质量评分法评估不同时点睡眠质量,并评价治疗后不同时点的疗效。结果术后1、3、7d及1、3个月时VAS评分分别为(1.48±1.27)、(1.35±1.19)、(1.13±0.97)、(2.96±1.94)、(3.34±2.14),较治疗前(6.57±1.53)明显降低,差异有统计学意义(P<0.01)。睡眠质量明显改善,术后各评价时点睡眠质量评分较术前差异有统计学意义(P<0.01);术后1、3、7d、1及3个月总体有效率分别为82.6%(19/23例),87.0%(20/23例),91.3%(21/23例),21.7%(5/23例),17.4%(4/23例)。结论短时程脊髓电刺激治疗亚急性期带状疱疹性神经痛短期效果佳,可迅速降低患者疼痛,明显改善睡眠质量。 Objective To observe the short-term effects of short-term spinal cord electrical stimulation (SCS) for the treatment of patients with sub-acute herpetic neuralgia. Methods Twenty-three patients with sub-acute herpetic neuralgia of both sexes, aged 60-80 years, were treated with short-term spinal electrical cord stimulation from January 2016 to June 2018 in the Department of Pain Medicine and Department of Neurology of Guizhou Provincial People's Hospital. SCS is a neuromodulation method by placing the stimulating electrode in the epidural space and using current to stimulate the posterior horn sensory neurons and posterior column conduction bundle. VAS was assessed before the treatment and at the 1 day, 3 days, 1 week, 1 month and 3 months after the treatment. Sleep quality score was evaluate quality of sleep at different times. Results The pain relief was remarkable at different times after SCS in all patients. The VAS was 1.48±1.27, 1.35±1.19, 1.13±0.97, 2.96±1.94, 3.34±2.14 at 1 day, 3 days, 1 week, 1 month and 3 months after the treatment respectively, with statistical difference compared with the pretreatment (6.57±1.53)(P<0.01). The effective rates were 82.6%(9/23), 87.0%(20/23), 91.3%(21/23), 21.7%(5/23), 17.4%(4/23) at 1 day, 3 days, 1 week, 1 month and 3 months after treatment respectively. The sleep quality scores were significantly increased at different times after stimulation SCS. Conclusion Short-term spinal cord electrical stimulation can alleviate pain and improve the quality of sleep for the patients with sub-acute herpetic neuralgia.
作者 余倩 黄玉瑛 贺纯静 Yu Qian;Huang Yuying;He Chunjing(Department of Neurology, Guizhou Provincial People's Hospital. Guiyang City 550002, China;Department of Pediatric, Guizhou Provincial People's Hospital, Guiyang City 550002, China;Department of Pain Medicine, Guizhou Provincial People's Hospital, Guiyang City 550002, China)
出处 《实用疼痛学杂志》 2019年第3期182-185,共4页 Pain Clinic Journal
关键词 电刺激 脊髓 带状疱疹 神经痛 亚急性 Electric stimulation Spinal cord Herpes zoster Neuralgia Sub-acute
作者简介 通信作者:黄玉瑛,Email: 1499084940@qq.com,电话:0851-85937171.
  • 相关文献

参考文献6

二级参考文献144

  • 1谭宪湖,谭冠先,何睿林,秦科.7神经阻滞联合药物治疗老年胸背部带状疱疹后神经痛的临床观察[J].临床麻醉学杂志,2005,21(1):33-35. 被引量:15
  • 2金小高,罗爱林,王金韬,张广雄,万丽,安珂,徐颖,田玉科.脊髓神经元和胶质细胞激活在三种神经病理性疼痛大鼠模型脊髓水平致痛机制中的作用[J].中华麻醉学杂志,2006,26(1):71-74. 被引量:11
  • 3黄宇光,徐建国.神经病理性疼痛临床诊疗学.北京:人民卫生出版社,2010:173. 被引量:2
  • 4Epstein LJ, Palmieri M. Managing chronic pain with spinal cord stimulation[J]. Mt Sinai J Med, 2012, 79(1) : 123-132. 被引量:1
  • 5Yang F, Carteret AF, Wacnik PW, et al. Bipolar spinal cord sti- mulation attenuates mechanical hypersensitivity at an intensity that activates a small portion of A-fiber afferents in spinal nerve-injured rats[J]. Neuroscienee, 2011, 29(199):470-480. 被引量:1
  • 6Shechter R, Yang F, Xu Q, et al. Conventional and kilohertz-freq- uency spinal cord stimulation produces intensity- and frequency- dependent inhibition of mechanical hypersensitivity in a rat model of neuropathic pain[J]. Anesthesiology, 2013, 119(2) :422-432. 被引量:1
  • 7Salo KL, Johanek LM, Sanada LS, et al. Spinal cord stimulation reduces mechanical hyperalgesia and glial cell activation in animals with neuropathic Pain[J]. Anesth Analg, 2014, 118(2):464-472. 被引量:1
  • 8Feldman P, Due MR, Ripsch MS, et al. The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain[Jl. J Neuroinflammation, 2012,9(180) :2-11. 被引量:1
  • 9Shibasaki M, Sasaki M, Miura M, et al. Induction of high mobility group box-1 in dorsal root ganglion contributes to pain hypersensitivity after peripheral nerve injury[Jl. Pain, 2010, 3(149):514-521. 被引量:1
  • 10Bennett GJ, Xie YK. A peripheral mononeuropathy in rat that prod- uces disordes of pain sensation like those seen in man [ J ] Pain, 1988,33 ( 1 ) : 87-107. 被引量:1

共引文献227

投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈
新型冠状病毒肺炎防控与诊疗专栏