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维生素A、E水平对子痫前期妊娠结局的影响

Effect of vitamin A and E levels on preeclampsia pregnancy outcome
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摘要 目的探讨子痫前期孕妇不同维生素A、E水平对妊娠结局的影响。方法选取义乌市妇幼保健院妇产科自2017年3月-2018年3月间收治的子痫前期孕妇120例作为实验对象,依据其12~20周测定血清维生素A、E水平进行分组,维生素A、E均正常组30例(对照组),维生素A正常/E缺乏组30例(观察a组),维生素A缺乏/E正常组30例(观察b组),维生素A、E均异常组30例(观察组),对比4组孕妇早产率、引产率、死胎以及新生儿窒息情况。结果观察组孕妇早产率高于其他3组,引产/死胎率略高于观察a组、观察b组和对照组,观察组新生儿窒息率显著高于其他3组,差异具有统计学意义(均P<0.05);对照组患者产后出血6例(20.00%),观察a组11例(36.67%),观察b组13例(43.33%),观察组17例(56.67%),观察组患者出血量高于其他3组,观察a组和b组平均出血量与对照组比较差异无统计学意义,新生儿Apgar评分对照组高于其他3组。结论子痫前期患者血清维生素A、E缺乏会增加早产、新生儿窒息、产后出血等不良妊娠结局,因此针对PE患者需加强对孕期维生素A、E等水平的监测,适当补充以改善妊娠结局。 Objective To investigate the effects of different vitamin A and E levels on pregnancy outcome in pregnant women with preeclampsia. Methods One hundred and twenty cases of preeclampsia pregnant women admitted to our hospital from March 2017 to March 2018 in Ukrainian Maternal and Child Health Hospital Obstetrics and Gynecology were selected as experimental subjects. The serum vitamin A and E levels were determined according to their 12-20 weeks. Vitamin A and E were normal. 30 patients in the group(control group), 30 patients with normal vitamin/E deficiency(observation group a), 30 patients with vitamin A deficiency/E normal group(observed group b), and 30 patients with abnormal vitamin A and E(observation group), comparing the preterm birth rate, induction rate, stillbirth and neonatal asphyxia in 4 groups of pregnant women. Results The preterm birth rate of the observation group was higher than that of the other 3 groups. The induction/abortion rate was slightly higher than that of the observation group a, the observation group b and the control group(all P>0.05). The neonatal asphyxia rate in the observation group was significantly higher than that in the other 3 groups. The significance of learning(all P<0.05);6 cases(20.00%) of postpartum hemorrhage in the control group, 11 cases(36.67%) in group a, 13 cases(43.33%) in group b, and 17 cases(56.67%) in observation group, observed The bleeding volume of the patients in the group was higher than that in the other 3 groups. The average blood loss of the group a and the b group was not significantly different from that of the control group. The neonatal Apgar score control group was higher than the other 3 groups. Conclusion Serum vitamin A and E levels in patients with preeclampsia have a greater impact on pregnancy outcomes. Pregnant women with normal vitamin levels have higher maternal and child safety.
作者 王璐 黄莉 WANG Lu;HUANG Li(Department of Obstetrics and Gynecology, Yiwu Maternal and Child Health Hospital, Yiwu, Zhejiang 322000, China)
出处 《中华全科医学》 2019年第7期1154-1156,共3页 Applied Journal Of General Practice
基金 国家卫生计生委医药卫生科技发展研究中心临床科研专项项目(W2015CAE047)。
关键词 子痫前期 维生素A 维生素E 妊娠结局 Preeclampsia Vitamin A Vitamin E Pregnancy outcome
作者简介 通信作者:王璐,E-mail:13868960581@163.com.
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