目的观察凉血解毒汤联合窄谱中波紫外线照射治疗玫瑰糠疹的临床疗效。方法将82例玫瑰糠疹患者随机分为治疗组43例和对照组39例,治疗组口服自拟凉血解毒汤和照射窄谱中波紫外线,对照组仅口服自拟凉血解毒汤,治疗1个月后观察两组玫瑰糠疹严重程度评分(pityriasis rosea severity score,PRSS),皮疹止痒、停发、消退时间和临床疗效。结果两组患者治疗后PRSS均显著减少(P<0.05);两组PRSS差值比较,差异无统计学意义(P>0.05)。两组患者皮疹止痒时间、皮疹停发时间、皮疹消退时间比较,差异均有统计学意义(P<0.05)。治疗组临床疗效优于对照组(P<0.05)。结论口服中药联合窄谱中波紫外线照射治疗玫瑰糠疹,疗效优于单用口服中药且不良反应小。
Objective To investigate the clinical effect of Liangxue Jiedu Decoction combined with narrow-band ultraviolet B (NB-UVB) in the treatment of pityriasis rosea. Methods A total of 82 patients with pityriasis rosea were randomly divided into treatment group with 43 patients and control group with 39 patients. The patients in the treatment group were given oral administration of self-made Liangxue Jiedu Decoction combined with NB-UVB, and those in the control group were given Liangxue Jiedu Decoction alone. Pityriasis Rosea Severity Score (PRSS), time to relief of itching, suspension of rash, and disappearance of rash, and clinical outcome were observed after 1 month of treatment. Results Both groups had a significant reduction in PRSS after treatment (P<0.05), and there was no significant difference in the reduction in PRSS between the two groups (P>0.05). There were significant differences between the two groups in the time to relief of itching, suspension of rash, and disappearance of rash (P<0.05). The treatment group had a significantly better clinical outcome than the control group (P<0.05). Conclusion Oral administration of Liangxue Jiedu Decoction combined with NB-UVB irradiation has a better clinical effect than oral administration alone in the treatment of pityriasis rosea, with few adverse effects.
Journal of Anhui University of Chinese Medicine
Narrow-band ultraviolet B