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消毒散联合干扰素对宫颈HR-HPV感染患者效果及HR-HPV的影响 预览

Effect of disinfection powder combined with interferon on HR-HPV in patients with cervical HR-HPV infection
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摘要 目的探讨消毒散联合干扰素对宫颈HR-HPV感染患者效果及HR-HPV的影响。方法选取2016年3月~2017年3月在我院接受治疗的宫颈HR-HPV感染患者68例,按照随机数字表法分为研究组和对照组。对照组应用消毒散进行治疗,研究组在对照组基础上联合应用干扰素治疗,对比两组患者的治疗效果、HPV转阴率及TCT变化情况。结果研究组患者的治疗有效率显著高于对照组(P<0.05);治疗3个月、6个月、12个月后研究组患者的HPV转阴率均显著高于对照组(P<0.05);治疗3个月、6个月、12个月后研究组的TCT未见HILM率显著高于对照组(P<0.05)。结论宫颈HR-HPV感染患者行消毒散联合干扰素治疗效果显著,不仅能够有效提高患者的HPV转阴率,还可以改善患者的TCT情况,值得在临床上进一步推广应用。 Objective To investigate the effect of disinfection powder combined with interferon on the effect of HR-HPV in patients with cervical HR-HPV infection. Methods A total of 68 patients with cervical HR-HPV infection who were treated in our hospital from March 2016 to March 2017 were enrolled. The patients were divided into study group and control group according to the random number table method. The control group was treated with disinfectant powder. The study group was treated with interferon on the basis of the treatment of the control group. The treatment effect, HPV negative rate and TCT change were compared between the two groups. Results The effective rate of treatment in the study group was significantly higher than that in the control group(P<0.05). The HPV negative rate in the study group was significantly higher than that in the control group at 3 months, 6 months, and 12 months after treatment(P<0.05). The HILM rate of TCT in the study group was significantly higher than that in the control group at 3 months, 6 months, and 12 months after treatment(P<0.05). Conclusion Disinfection powder combined with interferon in patients with cervical HR-HPV infection has significant difference, which is not only effective in improving the HPV negative rate, but also improving the patient's TCT.It is worthy of further clinical application.
作者 王燮斌 周燕 兰香 WANG Xiebin;ZHOU Yan;LAN Xiang(Department of Gynecology,Quzhou People's Hospital in Zhejiang Province,Quzhou,324000,China)
出处 《中国现代医生》 2019年第11期82-84,88共4页
基金 浙江省中医药科学研究基金项目(2016ZB138).
关键词 消毒散 干扰素 宫颈HR-HPV感染 治疗效果 转阴率 影响 TCT 不良反应 Disinfection powder Interferon Cervical HR-HPV infection Treatment effect Negative rate Effect TCT Adverse reactions
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