Objective To investigate the effect of grade Ⅱ-Ⅲ chemical burns( acid/alkali) on retinal nerve fiber layer( RNFL) thickness. Methods Patients with grade Ⅱ-Ⅲ chemical burns who revisited our hospital between January 2015 and June 2018 were recruited. Eyes with chemical burns were further divided into two groups,the acid chemical burns group and alkaline chemical burns group. While eyes without chemical burns were defined as the normal group. Intraocular pressure,average RNFL thickness,as well as RNFL thickness in the superior temporal,superior nasal,nasal,inferior nasal,inferior temporal and temporal quadrants were measured. Results Intraocular pressure showed no statistical difference among the three groups( P = 0. 973). No statistical differences were found in the average RNFL thickness or RNFL thickness in the superior temporal,superior nasal,nasal and temporal quadrants among the three groups( all with P> 0. 05). But there were statistical differences among the three groups in inferior temporal and inferior nasal RNFL thickness( P = 0. 008 and 0. 000,respectively). Conclusions Grade Ⅱ-Ⅲ chemical burns do not affect intraocular pressure,but it would result in a thinner RNFL thickness in some quadrants.
Journal of Clinical Ophthalmology
Acid/alkaline chemical burns
Retinal nerve fiber layer thickness