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上唇Warthin瘤合并黏液表皮样癌病例报道及文献复习 预览

Mucoepidermoid carcinoma arising in Warthin's tumor of the upper lip:a case report and review
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摘要 目的探讨1例上唇Warthin瘤合并黏液表皮样癌患者的诊断、治疗和预后,为此类疾病的诊断及治疗提供参考。方法分析吉林大学口腔医院1例上唇Warthin瘤合并黏液表皮样癌,整理患者的临床表现、治疗方法、病理特点及预后资料,同时结合文献对此类病例回顾分析。结果患者临床表现为左上唇一无痛性肿物1月余,行上唇肿物切除术,术后病理检查显示肿物为由Warthin瘤及黏液表皮样癌组成的杂交瘤,患者术后34个月无复发及远处转移。该类病例临床资料有限,经系统的治疗后,大多预后较好,未见复发及转移,生存率较高。结论上唇Warthin瘤合并黏液表皮样癌的杂交瘤临床罕见,其诊断需结合临床表现、影像学及病理学检查,扩大切除术后复发风险较低。 Objective To provide a reference for the diagnosis and treatment of mucoepidermoid carcinoma arising in Warthin's tumor of the lip by investigating the diagnosis,treatment and prognosis of the disease.Methods A case of mucoepidermoid carcinoma arising in Warthin's tumor of lip was reported,including the clinical manifestation,treat-ment,pathological characteristics and prognosis.The related literature was also reviewed and analyzed.Results A painless mass on the left lip lasting more than one month was found.Resection of the left lip was performed.Pathologi-cal examination showed that the tumor was a hybridoma composed of mucoepidermoid carcinoma and Warthin's tumor.There was no recurrence or distant metastasis after 34 months.To date,this type of disease has been rarely reported.Af-ter thorough resection,the prognosis and survival rate are promising in most cases,with no recurrence or metastasis.Conclusion Mucoepidermoid carcinoma in Warthin's tumor of the lip is rare.Clinical manifestations,imaging features and histological examination are useful when diagnosing the disease.Thorough resection will reduce the risk of disease recurrence.
作者 张宁 胡月 乔春燕 及昕 韩茹钰 孙兰芳 李明贺 韩成敏 ZHANG Ning;HU Yue;QIAO Chunyan;JI Xin;HAN Ruyu;SUN Lanfang;LI Minghe;HAN Chengmin(Department of Oral and Maxillofacial Surgery,Stomatology Hospital,Jilin University,Changchun 130021,China;Department of Oral Pathology,Stomatology Hospital,Jilin University,Changchun 130021,China)
出处 《口腔疾病防治》 2019年第4期250-254,共5页 Journal of Dental Prevention and Treatment
基金 吉林省卫生计生青年科技骨干培养计划项目(2016Q025) 吉林省科技发展计划优秀青年人才基金项目(20170520016JH) 吉林省科技厅优秀青年人才基金项目(20180520058H) 吉林省教育厅“十三五”科学技术项目(JJKH20170866KJ).
关键词 WARTHIN瘤 黏液表皮样癌 小唾液腺 病理诊断 手术治疗 Warthin tumor Mucoepidermoid carcinoma Minor salivary glands Pathological diagnosis Surgical treatment
作者简介 张宁,在读医学硕士,Email:465864076@qq.com;通信作者:李明贺,副主任医师,博士,Email:87832900@qq.com,Tel:0086-431-85579361;通信作者:韩成敏,教授,本科,Email:han-cm@sohu.com,Tel:0086-431-85579361.
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