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含金属纳米颗粒化妆品(皂和香波)的制备及性能评价 预览

Incorporation of Metallic Nanoparticles into Cosmetic Preparations and Assessment of Their Physicochemical and Utility Properties
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摘要 以绿茶提取物为还原剂和稳定剂制备了银和金纳米颗粒,进而化妆品中植入纳米银或纳米金,从而赋予了配方抗菌活性。通过UV-vis吸收光谱分析确认了金属纳米颗粒的成功制备及其在化妆品配方中的成功植入。通过动态光散射分析了金属纳米颗粒的尺寸大小及分布。利用扫描电子显微镜-X射线能谱对金属纳米颗粒和含金属纳米颗粒的妆品配方的微观结构进行了分析,评价了金属纳米颗粒从化妆品中的释放、在模拟皮肤中的渗透等生理性能,以黑曲霉菌为目标,测量了含金属纳米颗粒化妆品的抗菌性能。结果显示,金属纳米颗粒的引入并不会破坏化妆品配方的稳定性;它们虽然可以穿透皮肤,但短时间内是无法完成的;含金属纳米颗粒的化妆品对黑曲霉菌显示了较强的抗菌活性。 A method was developed for introducing metallic nanoparticles(nanoAg and nanoAu)into cosmetic compositions(shampoos and soaps).Embedding of silver or gold nanoparticles into the composition imparts antimicrobial activity.Physicochemical properties of the prepared formulations were characterized.To confirm the presence of metallic nanoparticles,a UV–vis study was conducted.The size of embedded nanoparticles was determined using dynamic light scattering.The micrometric structure of the obtained products was characterized using scanning electron microscopy with energydispersive X-ray spectroscopy(SEM-EDS)microscopy.A technique was developed for the assessment of nanoparticle release from cosmetic products as well as for the analysis of the penetration of nanoparticles through a model dermal membrane.The evaluation of accumulation of nanoparticles in model human body fluids was a crucial step in this study.The antimicrobial properties of final cosmetic formulations were studied using Aspergillus niger.The results confirmed that stable cosmetic formulations with embedded metallic nanoparticles were obtained.It was determined that nanoparticles are able to penetrate through a model dermal membrane.However,after 20 min of washing,the migration of nanoparticles was not confirmed.The obtained products exhibited biocidal activity against A.niger.
机构地区 江南大学
出处 《中国洗涤用品工业》 2019年第2期47-60,共14页 China Cleaning Industry
关键词 银纳米颗粒 金纳米颗粒 香波 肥皂 抗菌活性 silver nanoparticles gold nanoparticles shampoos soaps antimicrobial activity
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