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观察盐酸米诺环素联合替硝唑治疗慢性牙周炎的疗效和安全性 预览 被引量:2

To observe the efficacy and safety of minocycline combined with tinidazole in the treatment of chronic periodontitis
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摘要 目的分析盐酸米诺环素联合替硝唑治疗慢性牙周炎的效果以及安全性。方法选择来我院就医的慢性牙周炎患者(98例、2016年11月-2017年11月),通过就诊顺序单双号分组(分2组)。分别给予替硝唑、盐酸米诺环素联合替硝唑治疗,对比2组牙周相关临床指标情况、龈沟液相关炎症指标情况、不良反应发生情况。结果观察组牙周相关临床指标情况、龈沟液相关炎症指标情况与对照组数据之间相比较,P〈0.05,在不良反应发生情况中,2组数据均无差异性,P〉0.05。结论盐酸米诺环素联合替硝唑治疗慢性牙周炎安全有效。 Objective To analyze the effect and safety of minocycline combined with tinidazole in the treatment of chronic periodontitis. Methods A total of 98 patients with chronic periodontitis(98 patients, from November 22, 2016 to November 11, 2017) were enrolled in this study. The patients were treated with tinidazole and minocycline plus tinidazole respectively. The clinical data of periodontal related to the two groups were compared, and the status of gingival crevicular fluid-related inflammation and the incidence of adverse reactions were compared. Results The periodontal related clinical indexes, gingival crevicular fluid inflammation index in the observation group were compared with those in the control group(P〈0.05). There was no difference in the incidence of adverse reactions between the two groups(P〈0.05). Conclusion Minocycline combined with tinidazole is safe and effective in the treatment of chronic periodontitis.
作者 舒绍兵 罗金英 钟建鑫 SHU Shao-bing1 , LUO Jin-ying 2, ZHONG Jian-xin3 (1. Department of Stomatology, The First Clinic of Armed Police Corps Hospital, Chongqing, 401147,China;2.Department of Stomatology, Chongqing Sixth People's Hospital, Chongqing 400060,China;3. Department of Stomatology, the 324 Hospital of Chinese People's Liberation Army, Chongqing 400020,China
出处 《全科口腔医学杂志(电子版)》 2018年第12期1-2,共2页
关键词 盐酸米诺环素 替硝唑 慢性牙周炎 Minocycline hydrochloride Tinidazole Chronic periodontitis
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