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脂联素与急性ST段抬高型心肌梗死患者冠状动脉病变程度的相关性研究 被引量:3

Correlation between adiponectin and the severity of coronary artery disease in patients with acute ST elevation myocardial infarction
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摘要 目的分析血浆脂联素(APN)水平与急性ST段抬高型心肌梗死患者冠状动脉病变程度有无相关性及其临床意义。方法选取80例急性ST段抬高型心肌梗死患者为急性ST段抬高型心肌梗死组,另选择20例同期体检健康者为健康组。于入院次日清晨空腹测定两组APN水平,观察并分析冠状动脉病变程度与APN水平的相关性,比较不同梗死部位的APN水平。结果sT段抬高型心肌梗死组APN水平高于健康组(P〈0.05);血浆APN水平与冠状动脉病变评分呈正相关,相关系数r=0.695,P〈0.05。结论排除心力衰竭因土后,APN水平越高,急性心肌梗死患者冠状动脉病变程度越重。APN测定有助于急性心肌梗死患者的危险分层及预后判断。 Objective To analyze the correlation between plasma adiponectin (APN) level and the severity of coronary artery lesions in patients with acute ST-elevation myocardial infarction and investi- gate its clinical significance. Methods Eighty patients with acute ST-elevation myocardial infarction were selected as acute ST-elevation myocardial infarction group, at the same time, 20 cases of healthy people were selected as healthy group. At the next morning of admission the level of fasting APN in all patients was measured. The correlation between the severity of coronary artery lesions and the level of APN was observed and analyzed, and the APN levels at different infarction sites were compared. Results APN lev- el in acute ST-elevation myocardial infarction group was significantly higher than that in healthy group (P 〈 0. 05 ) ; the APN level was positively correlated with the severity of coronary artery lesions, the correlation co- efficient: r =0. 695, P 〈0. 05. Conclusions Taking no account of heart fail,e, the higher the level of APN, the more severe coronary artery disease in patients with acute myocardial infarction. APN determination con- duces to classify the security of ST-elevation myocardial infraction and assess the prognosis.
作者 师静梅 廉秋芳 梁引红 刘富强 王显利 张会琴 Department of Diabetic Cardiology, Tongde Hospital of Yuncheng City, Yuncheng 044000, China (Shi JM , Liang YH) ; Department of Cardiology, Xianyang Hospital of Yan' an University, Xianyang 712000, China ( Lian QF, Wang XL, Zhang HQ ) ; Department of Cardiology, Shanxi Provincial People' s Hospi- tal, Xi'an 710061, China ( Liu FQ)
出处 《中国实用医刊》 2017年第23期10-12,共3页 Chinese Journal of Practical Medicine
基金 陕西省自然科学基础研究计划项目(2016JM8123)
关键词 急性ST段抬高型心肌梗死 脂联素 冠状动脉 相关性 Acute ST-elevation myocardial infarction Adiponectin Coronary artery Correlation
作者简介 通信作者:廉秋芳,Email:n11528523@126.com
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