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2017年北美及欧洲儿科胃肠肝脏病和营养学会婴儿胆汁淤积性黄疸评估指南的胆道闭锁评估解读 被引量:4

Understanding the 2017 guideline of evaluation of cholestatic jaundice in infants recommended by the NASPGHAN and ESPGHAN from a biliary atresia perspective
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摘要 胆汁淤积(cholestasis)按病因可分为胆管性(梗阻、肝外胆管扩张或肝内胆管过小)和肝细胞性(膜转运体缺陷,遗传或代谢性障碍)。胆汁淤积性黄疸在足月产婴儿发病率约为1/2500,临床上常与新生儿内科性黄疸相混淆。婴儿胆汁淤积性黄疸常见的病因包括胆道闭锁(25%~40%)、遗传性疾病(25%)、胆总管结石或胆总管囊肿导致的肝外梗阻、代谢障碍(酪氨酸血症I型、半乳糖血症、先天性胆汁酸代谢障碍)、全垂体功能减退、Alagille综合征、感染及肠外营养相关的肝脏疾病。
作者 付康 李丹丹 冯杰雄 Fu Kang ,Li Dandan, Feng Jiexiong (Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030,China)
出处 《中华小儿外科杂志》 CSCD 2017年第7期495-499,共5页 Chinese Journal of Pediatric Surgery
基金 国家自然科学基金(81571478)
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