目的 评估大肠癌患者情绪状态及主观幸福度水平,为大肠癌患者制定合理的心理干预模式提供依据。方法 选取在中国医科大学附属第一医院肛肠外科手术前的大肠癌患者140例,健康对照组100例。应用汉密尔顿抑郁量表（HAMD）、汉密尔顿焦虑量表（HAMA）、纽芬兰纪念大学幸福度量表（MUNSH）。结果 大肠癌组与正常对照组在性别、年龄、婚姻、文化程度、职业及经济状况方面无统计学差异（P〉0.05）。大肠癌组抑郁、焦虑、负性情感、负向体验评分高于对照组,主观幸福度低于健康对照组（P〈0.05）。大肠癌伴抑郁状态患者的总体幸福度、正性体验评分低于非抑郁状态组;负性情感、负性体验评分高于非抑郁状态患者,差异有统计学意义（P〈0.01）。大肠癌患者抑郁评分与主观幸福度、正性情感、正性体验负相关,抑郁评分与负性情感、负向体验正相关（P〈0.01）。结论 不良情绪与主观幸福感之间可能具有相互影响、相互制约作用。
Objective To assess the emotional state and subjective well-being of patients with colorectal cancer, and to provide a basis for the development of a reasonable psychological intervention model for patients with colorectal cancer. Methods One hundred and forty cases of colorectal cancer in Department of Anorectal Surgery of the First Affiliated Hospital of China Medical University were selected, and 100 cases of healthy control group were selected. Results The differences between different genders, ages, marriage states, education levels, occupations and economic conditions of the coloreetal cancer group and normal control group had no statistical significance （P 〉 0. 05 ）. Depression, anxiety, negative emotion, negative experience score of the colorectal cancer group were higher than the control group, but subjective well-being was lower than that of the healthy control group （ P 〈 0. 05 ）. General well-being and the positive experience of patients with colorectal cancer in depression was lower than the non depressed state group of patients with colorectal cancer; negative emotion, negative experience scores were higher than non depressed patients, the difference was statistically significant （P 〈 0. 01）. There was positive correlation between depression scores and subjective well-being, positive emotions, positive experience, depression scores and negative emotions, positive correlation in patients with colorectal cancer （P 〈 0. 01 ）. Conclusion There may have mutual influence and restriction between negative emotion and subjective well-being.
Journal of Harbin Medical University