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戈舍瑞林联合腹腔镜治疗卵巢型子宫内膜异位症的疗效观察 预览 被引量:16

Observation on effect of goserelin and laparoscopy in treating ovarian type endometriosis
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摘要 目的探讨戈舍瑞林联合腹腔镜治疗卵巢型子宫内膜异位症的临床疗效。方法选择该院2014年4月至2016年5月收治的150例卵巢型子宫内膜异位症患者,按入院顺序分为普通组和手术联合组,每组各75例。普通组采用腹腔镜手术,术后口服孕三烯酮胶囊,手术联合组患者在普通组的基础上注射戈舍瑞林,治疗疗程为6个月。结果普通组治疗的有效率为83.90%,而手术联合组的有效率为98.67%,两组比较差异有统计学意义(P〈0.05);手术联合组的不良反应率低于普通组,差异有统计学意义(P〈0.05);两组治疗前的痛经、不孕、月经不调、性交疼痛、周期性直肠刺激症状、周期性膀胱刺激症状积分比较,差异无统计学意义(P〉0.05),治疗后比较差异有统计学意义(P〈0.05)。手术联合组的排卵恢复时间、月经恢复时间少于普通组,2年内妊娠率高于普通组,差异有统计学意义(P〈0.05)。结论戈舍瑞林联合腹腔镜治疗卵巢型子宫内膜异位症在临床治疗效果显著,具有良好的临床应用前景。 Objective To research the clinical effect of goserelin combined with laparoscopy in the treatment of ovarian type endometriosis.Methods One hundred and fifty patients with ovarian type endometriosis in our hospital from April 2014 to March2016were selected and divided into the common group and combined group according to the admission order,75 cases in each group.The common group adopted laparoscopic surgery and took the gestrinone capsule after operation,while the combined group was injected by goserelin on the basis of the common group.The treatment course lasted for 6months.Results The effective rate of the common group was 83.90%,which of the combined group was 98.67%,the difference was statistically significant(P〈0.05);the preoperative dysmenorrhea,infertility,irregular menstruation,dyspareunia,periodical rectal bladder irritation symptoms,periodical bladder irritation symptom scores before treatment had no statistical difference between the two groups(P〉0.05),but which after treatment had statistical difference between the two groups(P〈0.05).The ovulation recovery time and menstruation recovery time in the combined group were less than those in the common group,and pregnancy rate within two years was higher than that in the common group,the differences were statistically significant(P〈0.05).Conclusion Goserelin combined with laparoscopy in treating ovarian type endometriosis has significantly clinical effect and has good prospect of clinical application.
作者 王媛 杨敏 高成英 雷侠 WANG Yuan ,YANG Min ,GAO Chengying ,LEI Xia (Department of Gynecology ,Affiliated Hospital of Yanlan University ,Yanan ,Shaanxi 716000 ,China)
出处 《检验医学与临床》 CAS 2017年第6期781-782,785共3页 Laboratory Medicine and Clinic
关键词 戈舍瑞林 腹腔镜 卵巢型子宫内膜异位症 goserelin laparoscope ovarian type endometriosis
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