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胎盘Snail表达与前置胎盘和胎盘植入发病关系的研究 被引量:1

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摘要 目的研究胎盘Snail的表达与胎盘滋养细胞侵袭性及前置胎盘和胎盘植入发病的关系。方法选取60例孕产妇,分为胎盘植入组10例、前置胎盘组20例及对照组30例。采用免疫组织化学、Western Blot和RT-PCR检测各组胎盘母体面Snail的表达情况。结果胎盘植入组和前置胎盘组Snail蛋白的表达水平高于对照组,胎盘植入组Snail m RNA相对水平高于对照组,差异均有统计学意义(P〈0.05)。结论胎盘植入和前置胎盘患者胎盘母体面Snail表达升高可能与胎盘滋养细胞侵袭性增强及胎盘植入发病相关。
出处 《中国妇产科临床杂志》 CSCD 北大核心 2017年第2期173-175,共3页 Chinese Journal of Clinical Obstetrics and Gynecology
基金 国家卫生和计划生育委员会科研基金项目(WKJ-FJ-09) 福建省科技计划重点项目(2014Y0005)
作者简介 通信作者:颜建英Email:yanjy2004@126.com
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