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基于体素的形态学分析偏头痛患者灰质异常:Meta分析 预览 被引量:2

Analysis of gray matter abnormalities based on voxel-based morphometry in migraine patients: Meta-analysis
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摘要 目的 采用激活似然估计(ALE)的Meta分析方法,探讨偏头痛患者基于体素的形态学(VBM)分析所得的脑灰质改变。方法 在中国知网、PubMed和Embase数据库中检索从2000年1月—2015年6月间基于VBM的偏头痛患者灰质变化的文献,然后通过GingerALE软件包对所检索结果进行Meta分析。结果 检索后共纳入包括246例偏头痛患者和245名健康对照者的10项研究。偏头痛患者双侧额下回(BA44区)、右侧中央前回(BA43、44区)、双侧额中回(BA6、9区)、双侧扣带回前部(BA32区)、左侧扣带回(BA24区)、右侧颞上回(BA22区)、左侧岛叶(BA13区)、右侧顶下小叶(BA40区)灰质与健康对照者比较均显著减少(P均〈0.05)。结论 偏头痛患者脑灰质结构的改变为进一步研究与疼痛有关的脑神经网络的病理、生理机制提供了形态学依据。 Objective To investigate the changes of brain gray matter in migraine patients obtained by voxel-based morphometry (VBM) with meta-analysis of activation likelihood estimate (ALE).Methods A systematic search in CNKI, PubMed and Embase database from January, 2000 to June, 2015 was performed to identify VBM studies that analyzed changes of brain gray matter of migraine patients. A quantitative meta-analysis was performed using the ALE method.Results Ten studies consisting of 246 migraine patients and 245 healthy controls were included. Regional gray matter atrophy in migraine patients was found in the bilateral inferior frontal gyrus (BA44), right precentral gyrus (BA43, BA44), bilateral medial frontal gyrus (BA6, BA9), bilateral anterior cingulate (BA32), left cingulate gyrus (BA24), right superior temporal gyrus (BA22), right insula (BA13), right inferior parietal lobule (BA40).Conclusion A characteristic pattern of gray matter abnormalities in migraine patients can provide some morphological basis to further researchwork in pathology and physiology of neural network related pain.
作者 郑声妮 王怡洁 胡轶凯 李林 左荣跃 尹维刚 林荣 丁杰 陈一勇 ZHENG Shengni1 , WANG Yijie1 , HU Yikai1 , LI Lin2 , ZUO Rongyue3, YIN Weigang4, LIN Rong4 , DING Jie4 , CHEN Yiyong4(1. College of Science and Technology Ningbo University, Ningbo 315211, China ; 2. Department of Anatomy, Nanjing Medical University, Nanjing 210029, China ; 3. Department of Orthopedics, Affiliated Hospital of School of Medicine of Ningbo University, Ningbo 315000, China ; 4. Medical School of Ningbo University, Ningbo 315211, China)
出处 《中国医学影像技术》 CSCD 北大核心 2016年第10期1480-1484,共5页 Chinese Journal of Medical Imaging Technology
基金 宁波市自然科学基金(2014A610233).
关键词 偏头痛 激活似然估计 META分析 Migraine Activation likelihood estimate Meta-analysis
作者简介 [第一作者]郑声妮(1995-),女,浙江宁波人,在读本科。研究方向:人体解剖学。E-mail:zsnsunny88@qq.com [通信作者]陈一勇,宁波大学医学院,315211。Email:chenyiyong0519@nbu.edu.cn
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参考文献25

  • 1Cutrer FM, Black DP'. Imaging findings of migraine. Headache,2006,46(7):1095-1107. 被引量:1
  • 2Schwedt TJ, Dodick DW. Advanced neuroimaging of migraine.Lancet Neurol, 2009, 8(6) : 560-568. 被引量:1
  • 3Bhaskar S, Saeidi K, Horhani f),et al. Recent progress in mi-graine pathophysiology : Role of cortical spreading depression andmagnetic resonance imaging. Eur J Neurosci, 2013, 38( 1 1): 3540-3551. 被引量:1
  • 4Dai Z, Zhong J,Xiao I), et al. Gray matter correlates of migraineand gender effect : A meta analysis of voxel-based morphometrystudies. Neuroscience, 2015,299:88-96. 被引量:1
  • 5Matharu MS, Good C'D, May A, et al. No change in the struc-ture of the brain in migraine: A voxel-based morphometric .study.Eur J Neurol, 2003,10( 1): 53-57. 被引量:1
  • 6Tessitore A, Russo A, Giordano 八,et al. Disrupted defaultmode network connectivity in migraine without aura. J HeadachePain, 2013,14:89. 被引量:1
  • 7Obermann M, Wurthmann S, Steinberg BS, et al. Central ves-tibular system modulation in vestibular migraine. Cephalalgia,2014,34(13):1053-1061. 被引量:1
  • 8Rocca MA,Ceccarelli A, Falini A, et al. Brain gray matter chan-ges in migraine patients with T2-visible lesions: A 3-T MRIstudy. Stroke, 2006,37(7):1765-1770. 被引量:1
  • 9Kim JH,Suh SI, Seol HY, et al. Regional grey matter changesin patients with migraine: A voxe卜based morphometry study.Cephalalgia, 2008,28(6) : 598-604. 被引量:1
  • 10Schmidt-Wilcke T, Ganssbauer S,Neuner T, et al. Subtle greymatter changes between migraine patients and healthy controls.Cephalalgia, 2008, 28(1) : 1-4. 被引量:1

二级参考文献43

  • 1Muslimovic D, Post B, Speelman JD, et al. Cognitive profile of patients with newly diagnosed Parkinson disease. Neurology, 2005,65(8) : 1239-1245. 被引量:1
  • 2Aarsland D, Zaccai J, Brayne C. A systematic review of preva lenee studies of dementia in Parkinson's disease. Mov Disord, 2005,20(10) : 1255-1263. 被引量:1
  • 3Fernandez HH, Crueian GP, Okun MS, et al. Mild cognitive im pairment in Parkinson's disease: The challenge and the promise. Neuropsyehiatr Dis Treat, 2005,1 (1) : 37-50. 被引量:1
  • 4Gill DJ, Freshman A, Blender JA, et al. The montreal cognitive assessment as a screening tool for cognitive impairment in Parkinson's disease. Movement Disord, 2008, 23(7) : 1043-1046. 被引量:1
  • 5Pan PL, Song W, Shang HF. Voxel-wise meta-analysis of gray matter abnormalities in idiopathic Parkinson's disease. Eur J Neurol, 2012,19(2):199-206. 被引量:1
  • 6Burton EJ, McKeith IG, Burn DJ, et al. Cerebral atrophy in Parkinson's disease with and without dementia: A comparison with Alzheimer's disease, dementia with Lewy bodies and controls. Brain, 2001,127(Pt 4) :791-800. 被引量:1
  • 7Summerfield C, Junque C, Tolosa E, et al. Structural brain changes in Parkinson disease with dementia: A voxel-based mor phometry study. Arch Neurol, 2005,62(2) :281-285. 被引量:1
  • 8Benninger DH, Thees S, Kollias SS, et al. Morphological differences in Parkinson's disease with and without rest tremor. J Neurol, 2009,256(2):256-263. 被引量:1
  • 9Marvel CL, Desmond JE. Functional topography of the cerebellum in verbal working memory. Neuropsychol Rev, 2010. 20 (3) :271-279. 被引量:1
  • 10Beyer MK. Janvin CC, Larsen JP, et al. A magnetic resonance imaging study of patients with Parkinson's disease with mild cognitive impairment and dementia using voxel based morphometry. J Neurol Neurosurg Psychiatry, 2007,28(3):254-259. 被引量:1

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