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白癜风发病影响因素的Logistic回归分析

Logistic regression analysis of the influential factors of vitiligo
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摘要 目的:探讨临床上白癜风发病的相关因素,为白癜风的防治提供依据。方法:先对两组相关因素进行差异性分析,再将两组间差异有统计学意义的单因素进行多因素Logistic回归分析。结果:392例被调查者中,白癜风患者146例,非白癜风患者246名。单因素分析有统计学意义的因素:血型、皮肤病史、精神因素、暴晒史、蔬菜摄入量、饮酒、饮食规律、家族史、接触化学物质、日照时间。多因素Logistic回归分析显示,白癜风的独立危险因素有皮肤病史(OR=21.120)、经常接触化学物质(OR=2.340)、家族史(OR=2.430)、暴晒史(OR=2.094)、饮酒(OR=1.604);保护因素为适当的日光照射(OR=0.100)、规律饮食(OR=0.321)。结论:皮肤病史、家族史、经常接触化学物质、饮酒、暴晒史是白癜风发病的潜在独立危险因素,适当的日光照射、规律饮食是一种保护因素。 Objective: To explore the correlative factors of the incidence of vitiligo in clinical trails, and provide the basis for the prevention and treatment of vitiligo. Methods: First, the two groups of correlative factors were analyzed, and multivariate Logistic regression analysis were used to analyze the single factor whose difference between the two groups was statistically significant. Results: A total of 392 patients participated in the clinical trials, among them, 146 cases were vitiligo patients, 246 cases were non-vitiligo. Single factor analysis had statistical significance: blood type, skin history, mental factors, exposure history, vegetable intake, drinking, diet law, family history, exposure to chemical substances, sun exposure. Multivariate Logistic regression analysis showed that the independent risk factors of vitiligo were skin history(OR=21.120), regular contact with chemical substances(OR=2.340), family history(OR=2.430), exposure(OR=2.094), and drinking(OR=1.604);the protective factors were appropriate daylight exposure(OR=0.100), regular diet(OR=0.321). Conclusion: Skin history, family history, exposure to chemical substances, drinking and exposure to exposure history are potential independent risk factors of vitiligo, and appropriate sun exposure and regular diet are protective factors.
作者 韩宪伟 李铁男 张涛 HAN Xian-wei;LI Tie-nan;ZHANG Tao(Department of Dermatology,Shenyang Seventh People’s Hospital,Shenyang 110003,China;Liaoning University of Chinese Medicine,Liaoning 110032,China)
出处 《中华中医药杂志》 CAS CSCD 北大核心 2019年第2期811-814,共4页 China Journal of Traditional Chinese Medicine and Pharmacy
基金 辽宁省自然科学基金计划重点项目(No.20170540827) 沈阳市科技计划项目(No.17-230-9-22).
关键词 白癜风 相关因素 回归分析 危险因素 保护因素 Vitiligo Correlative factor Logistic regression analysis Risk factors Protective factors
作者简介 通讯作者:李铁男,辽宁省沈阳市和平区东纬路13号沈阳市第七人民医院皮肤科,邮编:110003,电话:024-23857361,E-mail:ltn8899@126.com;张涛,辽宁省沈阳市皇姑区崇山东路79号辽宁中医药大学,邮编:110032,电话:024-31961175,E-mail:787527077@qq.com。
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