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凉血通瘀方治疗慢性每日头痛40例临床观察 被引量:4

Clinical Observation on 40 Cases Chronic Daily Headache Treated with Liangxue Tongyu Decotion (凉血通瘀方)
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摘要 目的观察凉血通瘀方治疗慢性每日头痛的临床疗效及安全性。方法将80例慢性每日头痛患者随机分为治疗组和对照组各40例,治疗组给予凉血通瘀方口服,每日1剂;对照组给予普瑞巴林片1:7服,每次75mg,每日2次,两组均治疗60天。比较两组临床疗效,并分别于治疗前、治疗30天、治疗60天观察两组患者头痛发作频率、头痛持续时间、疼痛程度及伴随焦虑和抑郁情况。结果两组患者头痛发作频率、持续时间、疼痛程度在治疗30天及60天均较治疗前明显下降(P〈0.01),且治疗组头痛发作频率和持续时间在治疗30天时较对照组明显减少(P〈0.01)。治疗60天对照组焦虑状态的改善优于治疗组(P〈0.01)。治疗组临床控制率(25.00%)及总有效率(97.50%)均高于对照组(分别为5.00%及92.50%)(P〈0.01)。对照组共计8例患者出现不良反应,治疗组无明显不良反应。结论凉血通瘀方治疗慢性每日头痛疗效肯定,且安全性好。 Objective To observe the clinical efficacy and safety of Liangxue Tongyu Decoction (凉血通瘀方) in the treatment of chronic daily headache. Methods Eighty cases of chronic daily headache patients were randomly divided into treatment group and control group, with 40 cases in each group. The treatment group was given Liangxue Tongyu Decoction, 1 dose daily ; the control group was given pregabalin tablets orally, 75 mg each time, twice a day. Both groups were treated for 60 days, and the clinical efficacy were compared. The headache attack frequency, head- ache duration, pain degree and the accompanied anxiety and depression were observed before treatment, the 30th day and the 60th day of the treatment. Results The headache attack frequency, duration time and pain degree of the patients in two groups were significantly decreased at the 30th day and the 60th day of treatment compared with those before treatment (P 〈 0. 01 ). The headache attack frequency and duration time of headache in treatment group at the 30th day of treatment were significantly decreased compared with control group (P 〈0. 01 ). The improvement of anxiety state at the 60th day of the treatment in the control group was better than that in the treatment group (P 〈 0. 01 ). The clinical control rate (25%) and total effective rate (97.50%) in the treatment group were higher than those in the control group (5% and 92.50% respectively, P 〈 0.01). In the control group, there were 8 cases of adverse reactions, the treatment group had no obvious adverse reactions. Conclusion Liangxue Tongyu Decotion seems to have definite curative effect and good security in the treatment of chronic daily headache.
作者 仓志兰 CANG Zhilan (Traditional Chinese Medicine Hospital of Jiangsu Province, Nanjing, 210029)
出处 《中医杂志》 CSCD 北大核心 2016年第1期58-61,共4页 Journal of Traditional Chinese Medicine
关键词 慢性每日头痛 瘀热内阻 凉血通瘀方 普瑞巴林片 chronic daily headache blood stasis and heat resistance Liangxue Tongyu Decotion pregabalin tablets
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