Objective To explore the clinical effects of enteral nutrition combined with Rhubarb in treatment of severe acute pancreatitis（SAP）. Methods From August 2005 to August 2012 60 patients with severe acute pancreatitis cared at our hospital were selected,a random number table method was used to allocate the patients to a control group（EN,n=30）and an observation group（EN＋Rhubarb,n =30）.The clinical effect were observed and compared between the two groups. Results Group paired comparison of pre-treatment indexes between the observation group and the control group yielded no statistical difference（P〈0.05）,post-treatment indexes all decreased significantly,there were statistically significant differences by comparing with pre-treatment indexes（P 0.001）.The serum C-reactive protein（CRP）,interleukin-6（IL-6）,procalcitonin（PCT）levels of the observation group were lower than those of the control group,compared observation group with the control group,there were statistically significant differences（P 0.001）;the observation group had shorter enteral nutrition time and hospitalization time than the control group,there were statistically significant differences by group paired comparison（P 0.001）.Before treatment,group paired comparison of APACHEⅡ scores showed no statistical difference,after treatment the APACHEⅡ scores in the two groups decreased significantly,the APACHEⅡ scores of the observation group were lower than that of the control group,compared the APACHEⅡ scores between the observation group and the control group,there were statistically significant differences（P〈0.05）. Conclusion Enteral nutrition combined with Rhubarb can contribute to control inflammation reaction in SAP patients,to improve the patients＇ health condition,and has positively clinical application value.
Journal of Youjiang Medical College For Nationalities
severe acute pancreatitis