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肠内营养联合大黄对重症急性胰腺炎的临床疗效分析 预览 被引量:2

Efficacy of enteral nutrition combined Rhubarb in treatment of severe acute pancreatitis
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摘要 目的探讨肠内营养(EN)联合大黄对重症急性胰腺炎(SAP)的临床治疗效果。方法随机选择2005年8月~2012年8月本院的重症急性胰腺炎患者60例,根据数字表法将其分为对照组(EN)和观察组(EN+大黄),每组30例,观察并比较两组患者的临床疗效。结果治疗前,两组患者各项指标差异无统计学意义,治疗后均明显降低,与治疗前比较差异具有统计学意义(P均〈0.001);观察组血清C反应蛋白(CRP)、白细胞介素6(IL-6)、降钙素原(PCT)水平均低于对照组,差异具有统计学意义(P〈0.001);观察组患者肠内营养供给天数及住院天数均短于对照组,差异具有统计学意义(P〈0.001),治疗前,两组患者APACHEⅡ评分差异无统计学意义,治疗后均明显降低,观察组低于对照组,差异具有统计学意义(P〈0.05)。结论肠内营养联合大黄有助于控制SAP患者炎症反应,改善患者健康状况,具有积极的临床应用价值。 Objective To explore the clinical effects of enteral nutrition combined with Rhubarb in treatment of severe acute pancreatitis(SAP). Methods From August 2005 to August 2012 60 patients with severe acute pancreatitis cared at our hospital were selected,a random number table method was used to allocate the patients to a control group(EN,n=30)and an observation group(EN+Rhubarb,n =30).The clinical effect were observed and compared between the two groups. Results Group paired comparison of pre-treatment indexes between the observation group and the control group yielded no statistical difference(P〈0.05),post-treatment indexes all decreased significantly,there were statistically significant differences by comparing with pre-treatment indexes(P 0.001).The serum C-reactive protein(CRP),interleukin-6(IL-6),procalcitonin(PCT)levels of the observation group were lower than those of the control group,compared observation group with the control group,there were statistically significant differences(P 0.001);the observation group had shorter enteral nutrition time and hospitalization time than the control group,there were statistically significant differences by group paired comparison(P 0.001).Before treatment,group paired comparison of APACHEⅡ scores showed no statistical difference,after treatment the APACHEⅡ scores in the two groups decreased significantly,the APACHEⅡ scores of the observation group were lower than that of the control group,compared the APACHEⅡ scores between the observation group and the control group,there were statistically significant differences(P〈0.05). Conclusion Enteral nutrition combined with Rhubarb can contribute to control inflammation reaction in SAP patients,to improve the patients' health condition,and has positively clinical application value.
作者 邹浩 Zou Hao (Department of Gastroscope , Yangchun People ' s Hospital, Yangchun 529600,Guangdong,China)
出处 《右江民族医学院学报》 2015年第4期555-556,564共3页 Journal of Youjiang Medical College For Nationalities
关键词 胰腺炎 肠内营养 大黄 severe acute pancreatitis enteral nutrition Rhubarb
作者简介 E—mail:543376615@qq.com
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