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红景天苷药物动力学的研究进展 被引量:1

Research Progress in Pharmacokinetics of Salidroside
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摘要 综述国内外近年来红景天苷在生物样品中的提取方法、检测方法,动物体内吸收、分布、代谢、排泄规律以及药物动力学参数,分析红景天苷药物动力学研究中尚存在的问题,提出进一步开展红景天苷吸收机制、红景天苷代谢产物和生物利用度等研究,为红景天苷进一步研发和利用提供参考。 This paper reviewed the extraction methods and detection methods of salidroside,and its absorption,distribution,metabolism,excretion and even pharmacokinetic parameters in experimental animal during recent years.The still existed problems about pharmacokinetic study of salidroside were also analyzed.It is suggested that the further research on mechanism of absorption,metabolites and bioavailability of salidroside is needed,which is expected to provide evidence for the further development and application of salidroside.
作者 郭娜 韩雪娇 朱美宣 杨谦 GUO Na,HAN Xuejiao,ZHU Meixuan,YANG Qian[1. School of Municipal and Environmental Engineering,Harbin Institute of Technology, Harbin 150090 Heilongjiang, China; 2. Alkali Soil Natural Environmental Science Center, Northeast Forestry University, Key Laboratory of Saline-alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, Harbin 150040 Heilongjiang, China; 3. School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001 Heilongjiang, China)
出处 《中药新药与临床药理》 CAS CSCD 北大核心 2015年第2期264-267,共4页 Traditional Chinese Drug Research & Clinical Pharmacology
关键词 红景天苷 药物动力学 Salidroside Pharmacokinetics
作者简介 郭娜,女,博士,研究方向:生物活性物质利用。Email:guona0329@126.com 通讯作者:杨谦,博士,教授,博士生导师,研究方向:生物医学工程。Email:yangq@hit.edu.cn
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