目的了解拟输血者输血前血清中4项指标的基本状况,探讨相关检查的价值和必要性。方法对2007年11月-2011年12月在医院治疗有输血可能的住院患者74 212例,用酶联免疫法（ELISA）检测血清中乙型肝炎表面抗原（HBsAg）、丙型肝炎病毒抗体（抗-HCV）、苍白密螺旋体抗体（Anti-TP）和人类免疫缺陷病毒抗体（抗HIV1＋2）,并将结果进行统计分析。结果 74 212例拟输血者的HBsAg、抗-HCV、抗-HIV和Anti-TP有6 378例检出阳性,总阳性率为8.59%,2007-2011年分别为8.67%、5.22%、9.01%、9.81%和9.29%,以HBV阳性率最高,占6.52%,TP次之,占0.80%,HIV第3位,占0.63%,抗-HCV较少占0.26%,1项以上阳性者也占有较大的比例约占0.34%;年龄以30~39岁和40~49岁阳性数最多,分别占总阳性数的22.53%和22.81%。结论住院患者在拟输血前已有不同程度相关传染性疾病的感染,检测相关传染病感染指标对医务工作者的自我保护、有效控制医源性感染、为处理输血相关医疗纠纷提供证据以及方便患者及时治疗等均具有重要意义。
OBJECTIVE To study 4 indicators of serum before transfusion, and discuss the value and necessity of related inspection. METHODS A total of 74,212 cases （From Nov. 2007 to Dec. 2011） of inpatients with transfu- sion potential in our hospital were selected and collected. The hepatitis B surface antigen （HBsAg）, hepatitis C virus antibody （anti-HCV）, Treponema pallidum antibody （Anti-TP） and human immunodeficiency virus anti- body （anti-HIV1 ＋2） were detected by using enzyme-linked immunosorbent assay （ELISA） . All results were further analyzed through SPSS package. RESULTS A total of 6378 case in 74,212 were detected in one or more than one positive of HBsAg, anti-HCV, anti-HIV and Anti-TP 6378 cases detected. The total positive rate was 8.59%. The annual positive rate from 2007 to 2011 up to 8.67%, 5.22%, 9.01%, 9.81% and 9.29% , respec- tively. The HBsAg positive rate was the highest （6.52%）, and the rank form high to low as follows, Anti- TP was 0.82%, anti-HIV 0.62%, anti-HCV 0. 22%. Also there was high amount of patients with more than one index positive, around 0.34%. The age period between 30～39 and 40～49 showed more positive cases than other stage, up to 22.53% and 22.81% respectively. CONCLUSION Some of the hospitalized patients who need blood transfusion had varying degrees of infectious disease. Detection of infectious disease indicators will protect medical workers against secondary infection, and further provide effective control of iatrogenic infection. Taking together, transfusion-related medical detection will develop great treatment and care on patients and help to deal with med ical dispute.
Chinese Journal of Nosocomiology