Objective To investigate the effect of sanjiezhentong capsules on hepatocyte growth factor in patients with endometriosis.Methods 132 patients with endometriosis were equally,randomly divided into study group and control group. Patients in the control group were given gestrinone capsules,while the study group patients orally took sanjiezhentong capsules. The clinical efficacy,pain scores and serum levels of PRL,E2,CA-125,adiponectin,hepatocyte growth factor,AST and ALT of patients between the two groups were compared.Results After treatment,the treatment efficiency and serum adiponectin level of the study group were obviously higher than those of the control group( P < 0. 05). The pain scores and serum levels of PRL,E2,CA-125,hepatocyte growth factor,AST and ALT of the study group patients were significantly lower than those of the control group( P < 0. 05). Conclusion The sanjiezhentong capsules could effectively relieve the pain of endometriosis patients and improve their endocrine disorder,including regulating expression of adiponectin and hepatocyte growth factor,so as to promote their disease recovery.
Anhui Medical Journal