Objective:To observe the clinical effect of using Buzhong Yiqi Decoction combined with Compound Glutamine Enteric-coated Capsule in the treatment of diarrhea-predominant irritable bowel syndrome(IBS-D) of spleen-kidney Yang-deficiency syndrome.Methods:IBS-D of spleen-kidney Yang-deficiency syndrome was randomly divided into treatment group and controlled group.The treatment group was treated with Buzhong Yiqi Decoction plus Compound Glutamine Enteric-Coated Capsule,while the controlled group was only treated with Compound Glutamine Enteric-Coated Capsule.The two groups were treated for one month.The TCM syndrome index,IBS symptom severity score and health status before and after treatment were observed and recorded.Living quality index,etc.Results:The total clinical effective rate of the treatment group was better than that of the controlled group(88.9% vs 80.4%,P<0.05).The improvement of TCM syndromes(diarrhea,abdominal pain,fecal discharge,etc.) in the treatment group was better than that in the controlled group(P<0.05).The improvement of IBS symptom severity score and IBS related quality of life score in the treatment group were better than those in the controlled group(P<0.05).Conclusion:Buzhong Yiqi Decoction combined with Compound Glutamine Enteric-Coated Capsule has good clinical efficacy and safety in treating IBS-D of spleen-kidney Yang-deficiency syndrome.
Journal of Sichuan of Traditional Medicine
Irritable bowel syndrome
Buzhong Yiqi Decoction