Objective: To investigate the effect of a traditional Chinese medicine( Wen Baoyin) for treatment of delayed menorrhea caused by follicular development and ovulation delayed owing to Kidney-Yang-Deficient. Methods: 60 patients of such condition were randomly divided into experimental( Wen Baoyin) and control( oral gynecological reconstruction capsule) group with 30 patients in each group. After the treatment for three months,the curative effects,ovulation and the change of progesterone of patients were investigated. Results: 1. The improvement of curative effect of TCM syndrome: the effective rate of the experimental group was86.7% while the control group was 80%. There was no significant difference between two groups( P>0. 05); 2.Changes of TCM syndrome score: the symptom scores of patients decreased obviously for two groups after treatment with Wen Baoyin,group difference was statistically significant( P<0. 01),the observation group of TCM syndrome integral decreased significantly compared with the control group,there was significant differences between two groups( P<0. 05); 3. The ovulation rate is 60% for experimental group and 33. 3% for the control group. Obviously,two groups are significantly different from each other in this aspect.( P<0. 05); 4. The serum progesterone level in luteal stage: the experimental group was 52. 94±21. 384 nmol/L,while the control group was 37. 30 ± 12. 356 nmol/L,thus this value is statistically significant difference for two groups( P < 0. 05);Conclusions: The effect of both Wenbaoyin Decoction treatment and oral gynecological reconstruction capsule is significant for treatment of delayed menorrhea which caused by follicular development and ovulation delayed owing to Kidney-Yang-Deficient. Both of them can effectively improve the menstrual cycle and the related diseases,but the former significantly promote the follicular development,ovulation and luteal function.
Journal of Guiyang College of Traditional Chinese Medicine
reform of Wenbaoyin
Follicular development and ovulation