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蛇头穴刺络放血疗法治疗带状疱疹及其免疫机制的研究 被引量:4

A study of the therapy effect and immune mechanism of Snakeheads Hole inject therapy on herpes zoster patients
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摘要 目的探讨蛇头穴刺络放血疗法治疗带状疱疹的疗效及其免疫机制。方法将80例带状疱疹患者随机分成两组,实验组(蛇头穴刺络放血治疗组)40例,对照组(传统治疗组)40例,观察疗效并分别于治疗前及治疗后采集患者血液,检测T淋巴细胞亚群(CD3、CD4、CD8、CD4/CD8)及血清IL-2、IgG,以58例健康人为正常人组,对结果进行对比分析。结果带状疱疹患者治疗前CD3、CD4、CD4/CD8、IL-2、IgG水平显著低于正常人组,而CD。水平与正常人组无显著性差异。实验组治疗后,CD3水平显著上升,但仍低于正常人组,CD。水平显著降低,CD4/CD8、IL-2、IgG水平显著升高,达正常人水平。对照组治疗后,CD3水平显著上升,但仍低于对照组,CD4水平显著高于治疗前,CD8水平较治疗前显著降低,CD4/CD8、IL-2水平显著升高,达正常人水平,IgG水平与治疗前相比无显著性差异,仍低于正常人组。结论带状疱疹患者体内免疫状态的改变,参与了带状疱疹的发生与发展病程;患者CD,水平的持续低下,可能与带状疱疹患者病程迁延和复发有关系;蛇头穴刺络放血疗法对于提高患者IgG的含量,改善患者体液免疫方面,优于传统治疗方法。 Objective To survey the effect and immune mechanism of Snakehead Hole injection on herpes zoster patients. Meth- ods 80 cases of herpes zoster patients were separated into two groups ( experiment and contrast group ) randomly. T cell sub- group and blood IL - 2 IgG were detected with FAM and ELISA, While 58 healthy people were set as control. Results CD3 CD4 CD4/CD8 IL - 2 and IgG in herpes zoster patients were significantly lower than healthy people, after therapy CD3 rise significant- ly but still lower than healthy people, CD4 CD4/CD8 IL -2 and IgG rise and showed no significantly difference compared with normal control. In Snakeheads Hole infect therapy group , IgG rise and showed no significantly difference compared with healthy people, But in traditional therapy group, IgG rise but still lower than normal control. Conclusion Changes of immune function play an important role in the occurrence and development of herpes zoster patients ; Reducing continuously of CD3 may be connect- ed with persistent recurrence of Herpes zoster; Snakeheads Hole injection therapy is more effective in improving IgG level com- pared with traditional method.
作者 范永桥 杨正明 顾进 FAN Yong-qiao,YANG Zheng-ming, GU Jin ( Chinese Traditional Hospital of Lianyungang, Lianyungang, Jiangsu, 222002, China)
机构地区 连云港市中医院
出处 《时珍国医国药》 CAS CSCD 北大核心 2014年第4期1023-1024,共2页 Lishizhen Medicine and Materia Medica Research
关键词 带状疱疹 蛇头穴刺络放血疗法 免疫功能 Herpes zoster Snakehead Hole Injection Immune function
作者简介 作者简介:范永桥(1971-),女(汉族),江苏连云港人,连云港市中医院副主任检验技师,学士学位,主要从事医学检验工作.
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  • 1黄明炜,何小波,李宏.老年人免疫功能变化及对策[J].中国老年保健医学,2007(3):74-77. 被引量:12
  • 2张春梅,李宝强,于立勒.带状疱疹患者外周血T淋巴细胞亚群及迪赛片治疗的研究[J].皮肤病与性病,2004,26(3):10-11. 被引量:8
  • 3张一峰,李惠.水痘-带状疱疹病毒的免疫逃避[J].现代临床医学,2005,31(3):205-207. 被引量:5
  • 4张炜.带状疱疹病毒致病性和防治的研究进展[J].国外医学:皮肤性病学分册,1986,:257-257. 被引量:20
  • 5SCHMADER K. Herpes zoster in older adults [ J ]. Clin Infect Dis, 2001, 32(10) :1481 - 1486. 被引量:1
  • 6VOSSEN M T M, GENT M R, WEEL J F L, et al. Development of virus - specific CD4 + T cells on reexposure to varicella - zoster virus [J]. J Infect Dis, 2004, 190(1) :72 -82. 被引量:1
  • 7SVAHN A, LINDE A, THORSTENSSON R, et al. Development and evaluation of a flow-cytometric assay of specific cell-mediated immune response in activated whole blood for the detection of cell-mediated immunity against varicella - zoster virus [ J ]. Journal of Immunological Methods, 2003,277 ( 1 ) : 17 - 25. 被引量:1
  • 8DONG C, FLAVELL R A. Thl and Th2 cells[J]. Curr Opin Hematol, 2001, 8(1) :47 -51. 被引量:1
  • 9SALEM M L. Estrogen, a double edged sword : modulation of TH-2 and TH-2 mediated inflammations by differential regulation of TH1/TH2 cytokine production [ J ]. Curr Drug Targets Inflamm Allergy, 2004, 3(1) :97 -104. 被引量:1
  • 10ASANUMA H, SHAP M, MAECKER H T, et al. Frequencies of memory T cells specific for varicella-zoster virus, herpes simplex virus, and cytomegalovirus by intracellular detection of cytokine expression [J]. J Infect Dis, 2000, 181 (3) :859 - 866. 被引量:1

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