To observe the curative effect, IL-6, IL-12 and IL-18 detection in patients with acute cerebral infarction by fasudil hydrochloride, for accumulating clinical experience, directing clinical work. [Meth- ods ] 118 patients with acute cerebral infarction were divided into two groups. The routine treatment were applied in the control group, the routine treatment and fasudil hydrochloride were applied in the observation group. The cura- tive effect and the changes of IL-6, IL-12 and IL-18 detection were observed in two groups. [Results] The total ef- fective rate was obviously higher in the observation group than in the control group. The change values of IL-6, IL- l2 and IL--18 detection were obviously higher in the observation group than in the control group after treatment. [Conclusion] The fasudil hydrochloride can improve the curative effect, regulate the expressions of IL-6, IL-12 and IL-18 ：in patients with acute cerebral infarction, is worthy of being recommended in clinical treatment.
China Journal of Modern Medicine