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依达拉奉治疗急性脑出血的临床观察 预览 被引量:4

The Clinical Observation of Edaravone in the Treatment of Acute Cerebral Hemorrhage
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摘要 目的急性脑出血患者联合运用依达拉奉治疗,观察用药后临床效果。方法选择2009年6月至2011年12月间我院收治急性脑出血患者84例,随机分为观察组和对照组,各42例。观察组选择常规治疗基础上加用依达拉奉注射液治疗,对照组选择常规治疗,两组患者身高、体质量、出血部位等差异不大,P〉O.05,具有可比性。结果 治疗前两组患者ESS、ADL评分,无明显差异P〉O.05,治疗后两组患者ESS、ADL评分和两组患者治疗前后,都有明显差异P〈O.05,两组患者均未出现过敏反应,两组患者各出现1例肾损害情况,停药后一周复查,均自行好转。结论对于急性脑出血患者,配合运用依达拉奉,具有安全、有效、治疗效果好等优点,值得进一步推广运用。 Objective To observe the clinical effect of edaravone used in acute cerebral hemorrhage patients. Methods Selected 84 cases of acute cerebral hemorrhage patients from June 2009 to December 2011 in our hospital. All patients were randomly divided into two groups. The observation group has 42 cases which applied the edaravone injection treatment on the base of conventional treatment. The control group has 42 cases which applied the conventional treatmen. The height, weight, the site of bleeding and some other things of the two groups are not significant different, P〉0.05, so they are comparable. Results Before the treatment, ESS, ADL score of the two groups were not significantly different (P〉0.05). The ESS, ADL scores are significantly different after the treatment in the two groups and befor and after the treatment in the same group (P〈0.05). All the patients in the two groups don't have allergic reaction. There was one case respectively in the two groups who appeared renal damage. But they showed self improvement in the reexamination one week after stop using the drugs. Conclusion To the acute cerebral hemorrhage patients, with the use of edaravone, it has safe, Effective, better treatment effects and some other advantages. So it's worthy to fiarthe promotion and application.
作者 王雅斌 伍琳 林悦静 WANG Ya-bin, WU Lin, LIN Yue-jing (Shanwei Yihui Foundation Hospital, Shanwei 516600, China)
出处 《中国医药指南》 2012年第14期 28-29,共2页 Guide of China Medicine
关键词 依达拉奉 急性脑出血 疗效观察 Edaravone Acute cerebral hemorrhage Curative effect observation
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