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NS复合乳酸菌制剂对断奶仔猪免疫水平的影响 预览 被引量:14

Effects of NS-Lactobacillus Complex on Immunity Levels in Weaning Piglets
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摘要 选择二元杂交(杜/长)20日龄断奶仔猪90头,平均断奶体重8.99kg±1.60kg,按体重和性别分成3个处理组,每处理3个重复。A组为对照组,饲喂玉米、豆粕基础日粮;B组为基础日粮添加NS复合乳酸茵组2g/kg;C组为基础日粮添加抗生素组(2g/kg金霉素、0.25g/kg阿莫西林和0.125g/kg的支原净)。试验共30d,研究微生态制剂NS复合乳酸茵对断奶仔猪体液免疫和细胞免疫水平的影响。结果表明,试验30d时,NS复合乳酸茵组与对照组相比,断奶仔猪血清中的IgM含量和干扰素INF-7的含量分别高出19.70/4和10.2%,猪瘟病毒抗体阳性率高出33.3%,差异显著(P〈0.05);与NS复合乳酸茵组相比,抗生素组仔猪外周血T细胞CD8^+亚群的比例要高出79.2%,差异显著(P〈0.05)。NS复合乳酸茵制荆对加强仔猪体液免疫,维持仔猪的猪瘟、伪狂犬病毒抗体水平和促进机体细胞免疫具有良好效果。 A total of 90 crossbred piglets (1/2 Large white × 1/2 Duroc, 20-day-old, 8.99 kg±1. 60 kg ) were divided into 3 groups by weight and gender, with 3 replicates in each group and 10 piglets in each replicate. The 3 groups were as follows, control group (fed corn-soybean basal diet), NS-Lactobacillus group (added 2 g/kg NS-Lactobacillus complex in basal diet), antibiotic group (added 2 g/kg aureomycin, 0.25 g/kg amoxicillin and 0. 125 g/kg tiamulin in basal diet). The experiment time was 30 days. The humoral immunity, T lymphocyte subpopulations and the antibody levels of classical swine fever virus (CSFV) and pseudorabies virus (PRV) were assayed. The results showed as follows, the levels of IgM, IFN-y and the CSFV antibody positive rate in blood in NS-Lactobacillus group were increased by 19.7%, 10.2% and 33.3% compared with control group (P〈0.05). T lymphocyte CD8+ subpopulations in antibiotic group increased 79.2% compared with NS-Lactobacillus group (P〈0.05). These suggested that NS-Lactobacillus complex could improve humoral immunity, maintain the antibody levels of CSFV and PRV and increase cellular immunity of piglets.
作者 何颖 赵武 秦毅斌 赖胜基 胡庭俊 梁保忠 李斌 陈忠伟 胡旭 金锋 孙志勇 韦明宇 张恒博 蓝炳顺 HE Ying , ZHAO Wu, QIN Yi-bin , LAI Sheng-ji, HU Ting-jun, LIANG Bao-zhong , LI Bin , CHEN Zhong-wei , HU Xu, JIN Feng , SUN Zhi-yong , WEI Ming-yu , ZHANG Heng-bo , LAN Bin-shun (1. Veterinary Research Institute of Guangxi , Nanning, Guangxi,530001 ,China ; 2. Key Laboratory of Mental Health, Institute of Psychology, ChineseAcademy of Sciences, Beijing,100101,China; 3. University of Guangxi, Nanning, Guangxi,530004,Chinal 4. Livestock Research Institute of Guangxi , Nanning, Guangxi,530001 ,China)
出处 《动物医学进展》 CSCD 北大核心 2011年第12期 51-56,共6页 Progress In Veterinary Medicine
基金 广西科技攻关项目(桂科攻0992014-5)
关键词 NS复合乳酸菌 断奶仔猪 体液免疫 细胞免疫 T淋巴细胞亚群 NS-Lactobacillus complex weaning piglet humoral immunity cellular immunity T lympho-cyte subpopulation
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