期刊文献+

腹膜原发性腺癌3例临床病理分析 预览

Clinicopathological Characteristics of Primary Peritoneal Adenocarcinoma:an Analysis of 3 Cases
在线阅读 下载PDF
收藏 分享 导出
摘要 目的探讨腹膜原发性腺癌的病理形态学特征、诊断及鉴别诊断。方法对3例腹膜原发性腺癌进行形态学观察及免疫组化标记,并结合文献复习。结果患者均为老年女性,平均年龄67.7岁,以腹胀、腹水为主要临床表现;组织学表现2例为浆液性乳头状腺癌,1例为黏液腺癌。免疫组化:EMA、广谱CK、CEA、p53均阳性。结论腹膜原发性腺癌罕见,预后差,与卵巢癌、恶性间皮瘤及胃肠道转移癌易混淆;应依据形态学特点、结合免疫组化结果鉴别。 Objective To investigate the pathological features,diagnosis and differential diagnosis of primary peritoneal adenocarcinoma.Methods 3 cases of primary peritoneal adenocarcinoma were studied by light microscopy and immunohistochemistry,and the literature were reviewed.Results All cases were older female with a mean age of 67.7 years and the common clinical symptoms were abdominal distention and ascites,two cases were identified as serious papillary adenocarcinoma and the other was diagnosed as mucinous adenocarcinoma.Immunohistochemical staining showed positive in EMA,pan-CK,CEA,p53.Conclusion Primary peritoneal adenocarcinoma is a rare neoplasm with poor prognosis,which is easily confused with ovary carcinomas,malignant mesothelial tumors and metastatic tumors of digestive system,and immunohistochemistry helps in the differential diagnosis,combined with morphologicl features.
作者 张莹 ZHANG Ying.(Department of Pathology,Xishan People′s Hospital of Wuxi City,Wuxi 214011,China)
出处 《医学综述》 2011年第23期 3666-3668,共3页 Medical Recapitulate
关键词 腹膜原发性腺癌 临床病理 免疫组化 鉴别诊断 Primary peritoneal adenocarcinoma Clinical pathology Immunohistochemistry Differential diagnosis
  • 相关文献

参考文献10

二级参考文献40

  • 1张超 ,崔恒 ,赵彦 ,梁旭东 ,王朝华 ,李小平 ,沈丹华 ,王世军 ,魏丽惠 .原发性腹膜恶性肿瘤的治疗及预后分析[J].中华妇产科杂志,2005,40(7):464-468. 被引量:14
  • 2任艳彩,胡秀赟,张君娜.腹膜原发性腺癌的临床病理学观察[J].第四军医大学学报,2006,27(7):650-650. 被引量:5
  • 3李桂梅,李祥周,张佃乾,乐美兆.腹膜浆液性乳头状癌1例[J].诊断病理学杂志,2007,14(3):237-237. 被引量:3
  • 4Swerdlow M. Mesothelioma of the pelvic peritoneum resembling papillary cystadenocarcinoma of the ovary[J]. Am J Obstet Gynecol, 1959,77(1) : 197 - 200. 被引量:1
  • 5Lauchlan SC. The secondary Mullerian system revisited [ J ]. Int J Gynecol Pathol, 1994,13( 1 ) : 73 - 79. 被引量:1
  • 6Chu CS, Menzin AW, Leonard DG, et al. Primary peritoneal carcinoma: a review of the literature [ J ]. Obstet Gynecol Surv, 1999, 54(5) :323 - 335. 被引量:1
  • 7Shmueli E, Leider-Trejo L, Schwartz I, et al. Primary papillary serous carcinoma of the peritoneum in a man[J]. Ann Oncol, 2001, 12(4) : 563 - 567. 被引量:1
  • 8Khalifeh I, Munkarah AR, Lonardo F, et ol. Expression of Cox-2, CD34, Bcl-2, and p53 and survival in patients with primary peritoneal serous carcinoma and primary ovarian serous carcinoma [J]. Int J Gynecol Pathol, 2004,23(2):162- 169. 被引量:1
  • 9Mtaras MM, Bemheim J, Zehavi T, et al.Papillary serous carcinoma of the peritonecum coexisting with or after endometrial carcinoma [J]. Gynecol Oncol,2002,84(2):245 - 251. 被引量:1
  • 10Ordonez NG. Role of immunohistochemistry in distinguishing epithelial peritoneal mesotheliomas from peritoneal and ovarian serous carcinomas[J]. Am J Surg Pathol, 1998,22(10) : 1203 - 1214. 被引量:1

共引文献24

投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈