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当归和黄芪的比例变化对当归补血汤活性成分含量的影响 被引量:22

Affect of Ratio Changes of Radix Angelicae Sinensis to Radix Astragali in DangguJi Buxue Tang(DBT) on the Contents of Effective Constituents
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摘要 目的:通过研究当归、黄芪的比例变化对当归补血汤活性成分含量的影响探讨当归补血汤中当归、黄芪配伍比例的合理性,,方法:利用高效液相色谱法和比色法,测定了当归和黄芪配伍比例分别为:1:1,1:3,1:5,1:7,1:10的当归补血汤中阿魏酸、藁本内酯、黄芪甲苷、芒柄花素、毛蕊异黄酮及总多糖的含量。结果:在5个比例的当归补血汤中,李东垣的经典方当归、黄芪(1:5)中阿魏酸、黄芪甲苷、芒柄花素、毛蕊异黄酮及总多糖的含量最高。结论:当归补血汤中当归和黄芪1:5的配伍是合理的.应该遵循古人的用药经验。 Objective: To study the rationality of weight ratio of Radix Angelicae Sinensis to Radix Astragali in DBT by determined the contents of effective constituents in the different ratio of DBT. Method: The contents of astragaloside IV, calycosin, formononetin, ferulic acid, ligustilide and total polysaccharide in 5 ratios of DBT( Radix Angelicae Sinensis to Radix Astragali: 1 : 1, 1 : 3, 1 : 5,1 : 7, 1:10) were determined by HPLC and UV spectrophotometry. Result: Significantly, higher contents of astragaloside IV, calycosin, formononetin, ferulic acid and total polysaccharide were found in DBT with Radix Angelicae Sinensis and Radix Astragali in a 1 : 5 ratio. Conclusion : The 1 : 5 ratio of Radix Angelicae Sinensis and Radix Astragali in DBT described in 1247 A.D. by Li Dongyuan is reasonable and we should not change the formulation of DBT easily.
作者 赵奎君 钟萌 杨恩来 董婷霞 詹华强 Zhao Kuijun, Zhong Meng, Yang Enlai, Dong Tingxia, Zhan Huaqiang( Beijing Friendship Hospital, Capital Medical University, Beijing 100050, P. R. China;Department of Biology, The Hong Kong University of Science and Technology)
出处 《中国药师》 CAS 2006年第11期 1032-1034,共3页 China Pharmacist
关键词 当妇补血汤 配伍比例 活性成分含量 Danggui buxue Tang(DBT) Ratio of formulation Content of effective constituents
作者简介 赵奎君,男,硕士,教授,硕士生导帅,主研方向:中药活性物质及质量分析。Tel:(010)63138520 E-mail:zha01959@hotmail.com
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