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深圳市健康人群水痘-带状疱疹病毒血清流行病学调查 预览 被引量:17

Seroepidemiologicul survey of prevalence of varicella - zoster virus in healthy population in Shenzhen City.
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摘要 目的 了解深圳市人群水痘-带状疱疹病毒(VZV)的流行现状,为制定水痘防制措施提供依据。方法采用酶联免疫吸附试验(ELISA)对深圳市348名健康人群血清血标本进行抗-VZV IgG抗体检测。结果348份血清标本中,抗-VZV流行率为61.49%。1-5岁、6-10岁、11-15岁、16-20岁、21-30岁、31-40岁年龄别流行率分别11.36%,43.59%,70.83%,82.28%,93.18%,94.00%。水痘流行率以1-5岁最低,仅为11.36%,以后随年龄增长而升高。女性高于男性并有统计学意义(x^2=5.314,P〈0.05)。结论水痘病毒在人群中流行率很高,学龄前儿童为水痘的高危人群,托幼机构存在水痘爆发隐患,建议学龄前儿童普种水痘疫苗。 Objective To understand the prevalent status of varicella - zoster virus in the population of Shenzhen City and provide theoretic basis for the prevention of Varicella- zoster. Methods Serum antibody to varicella - zoster virus were detected in 348 samples by using ELISA. Results Age - specific prevalence rate of six age groups of 1 - 5,6 - 10,11 - 15,16 - 20,21 - 30 and 31 - 40 years were 11.36%, 43.59%, 70.83%, 82.28% ,93.18% and 94.00%, respectively. Sere - prevalence rate of 1- 5 age group was the lowest,it rose fast with age. The prevalence rate of varicella - zoster virus was higher in female (67.65 % ) than in male (55.62%). Conclusion The prevalence rate of varicella - zoster virus in popultion of Shenzhen City was high. Preschool children are the high - risk population. There is potential outbreak of varicella - zoster and all children in nuseries and kindergartens be immunized with varicella vaccine.
作者 王雅妮 WANG Ya - ni. ( Shekou Union Hospital, Shenzhen 518067, Guangdong, P, R, China)
出处 《中国热带医学》 CAS 2006年第7期 1166-1167,共2页 China Tropical Medicine
关键词 水痘-带状疱疹病毒(VZV) 流行率 水痘疫苗 Varicella - zoster Virus Sere - prevalence rate Vaccine
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