期刊文献+

分子水平上益生菌研究进展 预览 被引量:16

Investigation of Probiotics through Molecular Biology
在线阅读 下载PDF
收藏 分享 导出
摘要 益生菌是指能在生物体内存活,对生物体的健康有益的一类微生物.目前已经对益生菌的作用机理进行了深入和广泛的研究,获得了许多使用益生菌的经验.近些年来,分子生物学特别是基因工程技术的发展将益生菌的理论和应用研究推向了一个新的高度.从益生菌菌株的鉴定、菌株的遗传学修饰、益生菌功能基因组学和安全性等几个方面,综述了近年来国际上在分子水平上研究益生菌的技术方法、获得的主要研究成果和面临的挑战,并提出了益生菌研究的发展方向. Probiotics is commonly defined as viable microorganisms which exhibit a beneficial influences on the health of the host when they are ingested.History of research and applications is long enough.Mechanism of probiotics has been investigated widely and thoroughly,and lots of results are practicable in applications.Nowadays the development of molecular biology, especially genetic engineering technology, promotes both the theoretical research and applications of probiotics.This paper reviews the probiotics research progresses and trends in molecular biology,from the identification of strain,safety to genetic modification of probiotics.Moreover,future recommendation for the development of probiotics is given.
作者 袁铁铮 姚斌 YUAN Tie zheng YAO Bin (Feed Research Institute,Chinese Academy of Agricultural Sciences, Beijing 100081, China)
出处 《中国生物工程杂志》 CAS CSCD 2004年第10期 27-33,共7页 China Biotechnology
关键词 益生菌 分子水平 研究进展 生物体内 遗传学 健康 存活 菌株 基因工程技术 作用机理 Probiotics Molecular biology Safety Genetic modification
  • 相关文献

参考文献33

  • 1Fuller R. Probiotics: The scientific basis. London: Chapman&Hall,1992.1 - 7 被引量:1
  • 2Salminen S, Bouley C, Boutron-Ruault M C, et al. Functional food science and gastrointestinal physiology and function. Br J Nutr,1998,80(Suppl 1): S147 - S171 被引量:1
  • 3Shortt C, O' Brien J. Handbook of Functional Dairy Products. New York: CRC Press LLC, 2004.1 - 29 被引量:1
  • 4Tannock G W. Probiotics: a critical review. Norfolk, United Kingdom: Horizon Scientific Press, 1999 被引量:1
  • 5Fuller R. Probiotics 2: applications and practical aspects. London:Kluwer Academic Publishers, 1997 被引量:1
  • 6Yuan-Jun Lee. Handbook of Probiotics. New York: John Wiley&Sons, Inc, 1999 被引量:1
  • 7McCartney A L. Application of molecular biological methods for studying probiotics and the gut flora. British Journal of Nutrition,2002,88[Suppl 1]: S29 - S37 被引量:1
  • 8Franco L, Vladimir K, Camilla C, et al. Specific detection of a probiotic Lactobacillus strain in faecal samples by using multiplex PCR. FEMS Microbiology Letters, 1998,158: 273 - 278 被引量:1
  • 9Geoffroy M, Cyril G, Brigitte Q, ct al. Usc of green fluorescent protein to tag lactic acid bacterium strains under development as live vaccine vectors. Applied and Environmental Microbiology, 2000,66(1): 383 ~ 391 被引量:1
  • 10Oscar P K, Pascalle G G, Ruyter A de, et al. Controlled overproduction of proteins by lactic acid bacteria. Elsevier Science,1997,15: 135 - 140 被引量:1

同被引文献393

引证文献16

二级引证文献114

投稿分析
职称考试

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈